Immunotherapy as a downstaging therapy for liver transplantation.

Schwacha-Eipper, Birgit; Minciuna, Iulia; Banz, Vanessa; Dufour, Jean-François (2020). Immunotherapy as a downstaging therapy for liver transplantation. Hepatology, 72(4), pp. 1488-1490. Wiley 10.1002/hep.31234

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Locoregional therapies are downstaging methods for patients with hepatocellular carcinoma (HCC) outside Milan criteria. Sorafenib was the first systemic therapy tested in a neoadjuvant setting of liver transplantation, but with unsatisfactory results due to minimal response rate(1). Recently, immune checkpoint inhibitors have been shown to control HCC in a significant fraction of patients and to even induce complete response (2).

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Hepatology
04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Hepatologie
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Hepatologie

UniBE Contributor:

Schwacha-Eipper, Birgit; Banz Wüthrich, Vanessa and Dufour, Jean-François

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1527-3350

Publisher:

Wiley

Language:

English

Submitter:

Thi Thao Anh Pham

Date Deposited:

08 Dec 2020 08:40

Last Modified:

08 Dec 2020 08:40

Publisher DOI:

10.1002/hep.31234

PubMed ID:

32171041

Uncontrolled Keywords:

Hepatocellular carcinoma Immune checkpoint inhibitors Liver transplantation

BORIS DOI:

10.7892/boris.146470

URI:

https://boris.unibe.ch/id/eprint/146470

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