Ventricular Cryoinjury as a Model to Study Heart Regeneration in Zebrafish.

Marques, Ines J.; Sanz-Morejon, Andrés; Mercader, Nadia (2021). Ventricular Cryoinjury as a Model to Study Heart Regeneration in Zebrafish. Methods in molecular biology, 2158, pp. 51-61. Springer 10.1007/978-1-0716-0668-1_5

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Zebrafish have the capacity to regenerate most of its organs upon injury, including the heart. Due to its amenability for genetic manipulation, the zebrafish is an excellent model organism to study the cellular and molecular mechanisms promoting heart regeneration. Several cardiac injury models have been developed in zebrafish, including ventricular resection, genetic ablation, and ventricular cryoinjury. This chapter provides a detailed protocol of zebrafish ventricular cryoinjury and highlights factors and critical steps to be considered when performing this method.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Anatomy
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Anatomy > Functional Anatomy
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Anatomy > Anatomy

Graduate School:

Graduate School for Cellular and Biomedical Sciences (GCB)

UniBE Contributor:

dos Santos Marques, Ines Joao; Sanz Morejon, Andrés and Mercader Huber, Nadia Isabel

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1940-6029

Publisher:

Springer

Language:

English

Submitter:

Nadia Isabel Mercader Huber

Date Deposited:

15 Dec 2020 07:55

Last Modified:

15 Dec 2020 07:55

Publisher DOI:

10.1007/978-1-0716-0668-1_5

PubMed ID:

32857365

Uncontrolled Keywords:

Cryoinjury Fibrosis Heart Regeneration Ventricle apex Zebrafish

URI:

https://boris.unibe.ch/id/eprint/147035

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