Incidence and Outcome of Aneurysmal Subarachnoid Hemorrhage: The Swiss Study on Subarachnoid Hemorrhage (Swiss SOS).

Schatlo, Bawarjan; Fung, Christian; Stienen, Martin N; Fathi, Ali R; Fandino, Javier; Smoll, Nicolas R; Zumofen, Daniel; Daniel, Roy Thomas; Burkhardt, Jan-Karl; Bervini, David; Marbacher, Serge; Reinert, Michael; D Alonzo, Donato; Ahlborn, Peter; Mendes Pereira, Vitor; Roethlisberger, Michel; Seule, Martin; Kerkeni, Hassen; Remonda, Luca; Weyerbrock, Astrid; ... (2021). Incidence and Outcome of Aneurysmal Subarachnoid Hemorrhage: The Swiss Study on Subarachnoid Hemorrhage (Swiss SOS). Stroke, 52(1), pp. 344-347. Wolters Kluwer Health 10.1161/STROKEAHA.120.029538

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BACKGROUND AND PURPOSE

The purpose of this study was to assess nationwide incidence and outcomes of aneurysmal subarachnoid hemorrhage (aSAH). The Swiss SOS (Swiss Study on Subarachnoid Hemorrhage) was established in 2008 and offers the unique opportunity to provide this data from the point of care on a nationwide level.

METHODS

All patients with confirmed aneurysmal subarachnoid hemorrhage admitted between January 1, 2009 and December 31, 2014, within Switzerland were recorded in a prospective registry. Incidence rates were calculated based on time-matched population data. Admission parameters and outcomes at discharge and at 1 year were recorded.

RESULTS

We recorded data of 1787 consecutive patients. The incidence of aneurysmal subarachnoid hemorrhage in Switzerland was 3.7 per 100 000 persons/y. The number of female patients was 1170 (65.5%). With a follow-up rate of 91.3% at 1 year, 1042 patients (58.8%) led an independent life according to the modified Rankin Scale (0-2). About 1 in 10 patients survived in a dependent state (modified Rankin Scale, 3-5; n=185; 10.4%). Case fatality was 20.1% (n=356) at discharge and 22.1% (n=391) after 1 year.

CONCLUSIONS

The current incidence of aneurysmal subarachnoid hemorrhage in Switzerland is lower than expected and an indication of a global trend toward decreasing admissions for ruptured intracranial aneurysms.

REGISTRATION

URL: https://www.clinicaltrials.gov. Unique identifier: NCT03245866.

Item Type:

 Journal Article (Original Article)

Division/Institute:

 04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic and Interventional Neuroradiology
04 Faculty of Medicine > Faculty Institutions > Teaching Staff, Faculty of Medicine
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurosurgery
04 Faculty of Medicine > Department of Intensive Care, Emergency Medicine and Anaesthesiology (DINA) > Clinic of Intensive Care
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology

UniBE Contributor:

 Fung, Christian, Bervini, David, Goldberg, Johannes, Gralla, Jan, Z'Graggen, Werner Josef, Eisenring, Christian, Jakob, Stephan, Beck, Jürgen, Raabe, Andreas

Subjects:

 600 Technology > 610 Medicine & health

ISSN:

 1524-4628

Publisher:

 Wolters Kluwer Health

Language:

 English

Submitter:

 Martin Zbinden

Date Deposited:

 16 Dec 2020 11:46

Last Modified:

 05 Dec 2022 15:43

Publisher DOI:

 10.1161/STROKEAHA.120.029538

PubMed ID:

 33272133

Uncontrolled Keywords:

 Switzerland incidence intracranial aneurysm outcome patients stroke subarachnoid hemorrhage

BORIS DOI:

 10.7892/boris.149647

URI:

 https://boris.unibe.ch/id/eprint/149647

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