Effect of antimicrobial stewardship on antimicrobial prescriptions for selected diseases of dogs in Switzerland.

Lehner, Claudia; Hubbuch, Alina; Schmitt, Kira; Schuepbach-Regula, Gertraud; Willi, Barbara; Mevissen, Meike; Peter, Ruth; Muentener, Cedric R; Naegeli, Hanspeter; Schuller, Simone (2020). Effect of antimicrobial stewardship on antimicrobial prescriptions for selected diseases of dogs in Switzerland. Journal of veterinary internal medicine, 34(6), pp. 2418-2431. Wiley-Blackwell 10.1111/jvim.15906

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BACKGROUND

Antimicrobial stewardship programs (ASPs) are important tools to foster prudent antimicrobial use.

OBJECTIVE

To evaluate antimicrobial prescriptions by Swiss veterinarians before and after introduction of the online ASP AntibioticScout.ch in December 2016.

ANIMALS

Dogs presented to 2 university hospitals and 14 private practices in 2016 or 2018 for acute diarrhea (AD; n = 779), urinary tract infection (UTI; n = 505), respiratory tract infection (RTI; n = 580), or wound infection (WI; n = 341).

METHODS

Retrospective study. Prescriptions of antimicrobials in 2016 and 2018 were compared and their appropriateness assessed by a justification score.

RESULTS

The proportion of dogs prescribed antimicrobials decreased significantly between 2016 and 2018 (74% vs 59%; P < .001). The proportion of prescriptions in complete agreement with guidelines increased significantly (48% vs 60%; P < .001) and those in complete disagreement significantly decreased (38% vs 24%; P < .001) during this time. Antimicrobial prescriptions for dogs with AD were significantly correlated with the presence of hemorrhagic diarrhea in both years, but a significantly lower proportion of dogs with hemorrhagic diarrhea were unnecessarily prescribed antimicrobials in 2018 (65% vs 36%; P < .001). In private practices, in 2018 a bacterial etiology of UTI was confirmed in 16% of dogs. Prescriptions for fluoroquinolones significantly decreased (29% vs 14%; P = .002). Prescriptions for antimicrobials decreased significantly in private practices for RTI (54% vs 31%; P < .001).

CONCLUSION

Antimicrobials were used more prudently for the examined indications in 2018 compared to 2016. The study highlights the continued need for ASPs in veterinary medicine.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV)
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > Small Animal Clinic > Small Animal Clinic, Internal Medicine
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > Small Animal Clinic
05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH) > Veterinary Public Health Institute
05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH) > Veterinary Pharmacology and Toxicology
05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH)

UniBE Contributor:

Lehner, Claudia; Schüpbach, Gertraud Irene; Mevissen, Meike and Schuller, Simone

Subjects:

600 Technology > 630 Agriculture

ISSN:

0891-6640

Publisher:

Wiley-Blackwell

Funders:

[4] Swiss National Science Foundation

Language:

English

Submitter:

Simone Schuller

Date Deposited:

11 Jan 2021 10:50

Last Modified:

11 Jan 2021 10:57

Publisher DOI:

10.1111/jvim.15906

PubMed ID:

33112451

Uncontrolled Keywords:

antibiotic antimicrobial resistance dog guidelines prescribing habits

BORIS DOI:

10.7892/boris.150745

URI:

https://boris.unibe.ch/id/eprint/150745

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