Benzing, Valentin; Siegwart, Valerie; Spitzhüttl, Janine; Schmid, Jürg; Grotzer, Michael; Roebers, Claudia M.; Steinlin, Maja; Leibundgut, Kurt; Everts, Regula; Schmidt, Mirko (2021). Motor ability, physical self-concept and health-related quality of life in pediatric cancer survivors. Cancer medicine, 10(5), pp. 1860-1871. Wiley 10.1002/cam4.3750
|
Text
cam4.3750.pdf - Published Version Available under License Creative Commons: Attribution (CC-BY). Download (280kB) | Preview |
|
|
Text
PCS_late_effects_pdf.pdf - Accepted Version Available under License Creative Commons: Attribution (CC-BY). Download (564kB) | Preview |
Background: Cancer survivorship is frequently associated with severe late effects. However, research into pediatric cancer survivors on late effects in motor ability, physical self-concept and their relationship to quality of life is limited.
Methods: Using multiple regression analyses, 78 pediatric cancer survivors and 56 typically developing children were compared in motor ability, physical self-concept and health-related quality of life. In addition, mediational multi-group analyses between motor ability (independent variable), physical self-concept (mediator) and quality of life (dependent variable) were calculated.
Results: Pediatric cancer survivors had a lower motor ability (gHedges = 0.863), a lower physical self-concept with regard to several scales of the PSDQ-S (gHedges = 0.318-0.764) and a higher relative risk for a below average quality of life than controls (RR = 1.44). Children with a history of cancer involving the central nervous system showed poorer motor ability compared to those without central nervous system involvement (gHedges = 0.591). Furthermore, the physical self-concept significantly mediated the relationship between motor ability and quality of life in pediatric cancer survivors but not in typically developing children.
Conclusions: Results show the importance of monitoring and supporting the development of motor ability in the aftercare of pediatric cancer survivors. Physical activity interventions may be advisable to prevent physical activity-related late effects and potentially improve related psychosocial variables such as quality of life.