Bolondi, Luigi; Burroughs, Andrew; Dufour, Jean-François; Galle, Peter R; Mazzaferro, Vincenzo; Piscaglia, Fabio; Raoul, Jean Luc; Sangro, Bruno (2012). Heterogeneity of patients with intermediate (BCLC B) Hepatocellular Carcinoma: proposal for a subclassification to facilitate treatment decisions. Seminars in liver disease, 32(4), pp. 348-59. New York, N.Y.: Thieme Medical Publishers 10.1055/s-0032-1329906
Full text not available from this repository.The intermediate stage of hepatocellular carcinoma (HCC) comprises a highly heterogeneous patient population and therefore poses unique challenges for therapeutic management, different from the early and advanced stages. Patients classified as having intermediate HCC by the Barcelona Clinic Liver Cancer (BCLC) staging system present with varying tumor burden and liver function. Transarterial chemoembolization (TACE) is currently recommended as the standard of care in this setting, but there is considerable variation in the clinical benefit patients derive from this treatment.In April 2012, a panel of experts convened to discuss unresolved issues surrounding the application of current guidelines when managing patients with intermediate HCC. The meeting explored the applicability of a subclassification system for intermediate HCC patients to tailor therapeutic interventions based on the evidence available to date and expert opinion. The present report summarizes the proposal of the expert panel: four substages of intermediate HCC patients, B1 to B4.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Hepatology |
UniBE Contributor: |
Dufour, Jean-François |
ISSN: |
0272-8087 |
Publisher: |
Thieme Medical Publishers |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:38 |
Last Modified: |
05 Dec 2022 14:11 |
Publisher DOI: |
10.1055/s-0032-1329906 |
PubMed ID: |
23397536 |
Web of Science ID: |
000311657000011 |
URI: |
https://boris.unibe.ch/id/eprint/15199 (FactScience: 222491) |
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