A review of methods for addressing components of interventions in meta-analysis.

Petropoulou, Maria; Efthimiou, Orestis; Rücker, Gerta; Schwarzer, Guido; Furukawa, Toshi A; Pompoli, Alessandro; Koek, Huiberdina L; Del Giovane, Cinzia; Rodondi, Nicolas; Mavridis, Dimitris (2021). A review of methods for addressing components of interventions in meta-analysis. PLoS ONE, 16(2), e0246631. Public Library of Science 10.1371/journal.pone.0246631

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Many healthcare interventions are complex, consisting of multiple, possibly interacting, components. Several methodological articles addressing complex interventions in the meta-analytical context have been published. We hereby provide an overview of methods used to evaluate the effects of complex interventions with meta-analytical models. We summarized the methodology, highlighted new developments, and described the benefits, drawbacks, and potential challenges of each identified method. We expect meta-analytical methods focusing on components of several multicomponent interventions to become increasingly popular due to recently developed, easy-to-use, software tools that can be used to conduct the relevant analyses. The different meta-analytical methods are illustrated through two examples comparing psychotherapies for panic disorder.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of General Internal Medicine (DAIM) > Clinic of General Internal Medicine > Centre of Competence for General Internal Medicine
04 Faculty of Medicine > Medical Education > Institute of General Practice and Primary Care (BIHAM)
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Social and Preventive Medicine (ISPM)

UniBE Contributor:

Efthimiou, Orestis; Del Giovane, Cinzia and Rodondi, Nicolas

Subjects:

600 Technology > 610 Medicine & health
300 Social sciences, sociology & anthropology > 360 Social problems & social services

ISSN:

1932-6203

Publisher:

Public Library of Science

Funders:

[4] Swiss National Science Foundation

Language:

English

Submitter:

Doris Kopp Heim

Date Deposited:

09 Feb 2021 16:06

Last Modified:

13 Mar 2021 20:41

Publisher DOI:

10.1371/journal.pone.0246631

PubMed ID:

33556155

BORIS DOI:

10.48350/152080

URI:

https://boris.unibe.ch/id/eprint/152080

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