Cardiomyopathy Associated With Coronary Arteriosclerosis in Free-Ranging Eurasian Lynx (Lynx lynx carpathicus).

Ryser-Degiorgis, Marie-Pierre; Robert, Nadia; Meier, Roman Kaspar; Zürcher-Giovannini, Samoa; Pewsner, Mirjam; Ryser, Andreas; Breitenmoser, Urs; Kovacevic, Alan; Origgi, Francesco C. (2020). Cardiomyopathy Associated With Coronary Arteriosclerosis in Free-Ranging Eurasian Lynx (Lynx lynx carpathicus). Frontiers in veterinary science, 7, p. 594952. Frontiers Media 10.3389/fvets.2020.594952

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The Eurasian lynx (subspecies Lynx lynx carpathicus) was reintroduced to Switzerland in the 1970's. Health monitoring of the reintroduced population started in the late 1980's. Since then, six lynx have been found affected by a myocardial disease. The earliest case was an animal that died after a field anesthesia. Two lynx were found dead, two were euthanized/culled because of disease signs, and one was hit by car. Two had a heart murmur at clinical examination. At necropsy, the first animal showed only lung edema but the other five had cardiomegaly associated with myocardial fibrosis. Three had multisystemic effusions. Histological examination of all six lynx showed mild to severe, multifocal, myocardial interstitial and perivascular fibrosis along with multifocal myocyte degeneration and loss, and replacement fibrosis. Moderate to severe multifocal arteriosclerosis with associated luminal stenosis of the small and medium-sized intramural coronary arteries and the presence of Anitschkow cells was also observed. The heart lesions may have led to sudden death in the first case and to a chronic right-sided heart failure in the remaining. None of the lynx showed lesions or signs suggestive of an acute or subacute infection. Given the common geographic origin of these animals and the severe loss of heterozygocity in this population, a genetic origin of the disease is hypothesized.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Center for Fish and Wildlife Health (FIWI)
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > Small Animal Clinic

UniBE Contributor:

Ryser, Marie Pierre; Robert, Nadia; Meier, Roman Kaspar; Zürcher, Samoa Micheline; Pewsner, Mirjam; Kovacevic, Alan and Origgi, Francesco

Subjects:

500 Science > 590 Animals (Zoology)
600 Technology > 610 Medicine & health
600 Technology > 630 Agriculture

ISSN:

2297-1769

Publisher:

Frontiers Media

Language:

English

Submitter:

Achim Braun Parham

Date Deposited:

17 Feb 2021 13:28

Last Modified:

14 Mar 2021 13:05

Publisher DOI:

10.3389/fvets.2020.594952

PubMed ID:

33409296

Uncontrolled Keywords:

cardiomegaly heart failure heart murmur lung edema myocardial fibrosis pathology wildlife

BORIS DOI:

10.48350/152278

URI:

https://boris.unibe.ch/id/eprint/152278

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