The vitamin D receptor gene bAt (CCA) haplotype impairs the response to pegylated-interferon/ribavirin-based therapy in chronic hepatitis C patients

Baur, Katharina; Mertens, Joachim C; Schmitt, Johannes; Iwata, Rika; Stieger, Bruno; Frei, Pascal; Seifert, Burkhardt; Bischoff Ferrari, Heike A; von Eckardstein, Arnold; Müllhaupt, Beat; Geier, Andreas; Swiss Hepatitis C Cohort Study Group, (2012). The vitamin D receptor gene bAt (CCA) haplotype impairs the response to pegylated-interferon/ribavirin-based therapy in chronic hepatitis C patients. Antiviral therapy, 17(3), pp. 541-7. London: International Medical Press 10.3851/IMP2018

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Chronic hepatitis C infection is a major cause of end-stage liver disease. Therapy outcome is influenced by 25-OH vitamin D deficiency. To further address this observation, our study investigates the impact of the vitamin D receptor (NR1I1) haplotype and combined effects of plasma vitamin D levels in a well-described cohort of hepatitis C patients.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Hepatology

UniBE Contributor:

Dufour, Jean-François

ISSN:

1359-6535

Publisher:

International Medical Press

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:38

Last Modified:

17 Mar 2015 21:30

Publisher DOI:

10.3851/IMP2018

PubMed ID:

22300961

Web of Science ID:

000303988000014

URI:

https://boris.unibe.ch/id/eprint/15237 (FactScience: 222532)

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