Mental health and its associations with weight in women with gestational diabetes mellitus. A prospective clinical cohort study.

Gilbert, Leah; Rossel, Jean-Benoît; Quansah, Dan Yedu; Puder, Jardena J; Horsch, Antje (2021). Mental health and its associations with weight in women with gestational diabetes mellitus. A prospective clinical cohort study. Journal of psychosomatic research, 146, p. 110489. Elsevier 10.1016/j.jpsychores.2021.110489

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OBJECTIVE

Despite the prevalence of depression in women with gestational diabetes mellitus (GDM) and the relationship between mental health (depression and well-being) and metabolic health, little is known about mental health or its metabolic impact in GDM pregnancy. This prospective clinical cohort study aimed to investigate associations between 1) well-being and depression, and 2) mental health and weight/weight gain in women with GDM.

METHODS

We included 334 pregnant women with GDM treated at a Swiss University Hospital between January 2016 and December 2018. They completed two self-report questionnaires: The World Health Organization well-being index (WHO-5) at the first (29 weeks of gestation) and last (36 weeks of gestation) GDM visits during pregnancy and the Edinburgh Postnatal Depression Scale (EPDS) at the first GDM visit. A cut-off of ≥11 was selected for this questionnaire to indicate the presence of elevated depression scores.

RESULTS

There was an inverse association between the well-being and depression total scores at the first GDM visit during pregnancy (r = -0.55; p < 0.0001). Elevated depression scores at the first GDM visit were associated with subsequent weight gain in GDM pregnancy (β = 1.249; p = 0.019).

CONCLUSION

In women with GDM, elevated depression scores during pregnancy are prospectively associated with weight gain. Depression symptoms should therefore be screened for and treated in women with GDM to reduce the risks associated with excessive weight gain during pregnancy.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > Department of Clinical Research (DCR)

UniBE Contributor:

Rossel, Jean-Benoît

ISSN:

0022-3999

Publisher:

Elsevier

Funders:

[4] Swiss National Science Foundation

Language:

English

Submitter:

Andrea Flükiger-Flückiger

Date Deposited:

27 Apr 2021 17:51

Last Modified:

20 Feb 2024 14:16

Publisher DOI:

10.1016/j.jpsychores.2021.110489

PubMed ID:

33895430

Uncontrolled Keywords:

Depression EPDS Pregnancy WHO-5 Weight Well-being

BORIS DOI:

10.48350/156079

URI:

https://boris.unibe.ch/id/eprint/156079

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