Platelet Transfusion-Insights from Current Practice to Future Development.

Capraru, Annina; Jalowiec, Katarzyna Aleksandra; Medri, Cesare; Daskalakis, Michael; Zeerleder, Sacha Sergio; Mansouri Taleghani, Behrouz (2021). Platelet Transfusion-Insights from Current Practice to Future Development. Journal of clinical medicine, 10(9) MDPI 10.3390/jcm10091990

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Since the late sixties, therapeutic or prophylactic platelet transfusion has been used to relieve hemorrhagic complications of patients with, e.g., thrombocytopenia, platelet dysfunction, and injuries, and is an essential part of the supportive care in high dose chemotherapy. Current and upcoming advances will significantly affect present standards. We focus on specific issues, including the comparison of buffy-coat (BPC) and apheresis platelet concentrates (APC); plasma additive solutions (PAS); further measures for improvement of platelet storage quality; pathogen inactivation; and cold storage of platelets. The objective of this article is to give insights from current practice to future development on platelet transfusion, focusing on these selected issues, which have a potentially major impact on forthcoming guidelines.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Haematology and Central Haematological Laboratory
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > Unit Childrens Hospital > Forschungsgruppe Hämatologie (Erwachsene)

UniBE Contributor:

Capraru, Annina; Jalowiec, Katarzyna Aleksandra; Medri, Cesare; Daskalakis, Michael; Zeerleder, Sacha Sergio and Mansouri Taleghani, Behrouz

Subjects:

600 Technology > 610 Medicine & health

ISSN:

2077-0383

Publisher:

MDPI

Language:

English

Submitter:

Pierrette Durand Lüthi

Date Deposited:

28 Jun 2021 15:54

Last Modified:

28 Jun 2021 15:54

Publisher DOI:

10.3390/jcm10091990

PubMed ID:

34066360

Uncontrolled Keywords:

cold stored platelet concentrates platelet additive solutions platelet pathogen inactivation/reduction platelet transfusion alternatives platelet transfusion guidelines

BORIS DOI:

10.48350/156796

URI:

https://boris.unibe.ch/id/eprint/156796

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