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Perroud, Camille; Thurian, Dario; Andres, Martin; Künzi, Arnaud; Wiedemann, Gertrud; Zeerleder, Sacha; Bacher, Ulrike; Pabst, Thomas; Banz, Yara; Porret, Naomi; Rebmann, Ekaterina (2023). Effect of MAPK activation via mutations in NRAS, KRAS and BRAF on clinical outcome in newly diagnosed multiple myeloma. Hematological oncology, 41(5), pp. 912-921. Wiley 10.1002/hon.3208
Ruggeri, Tiphaine; De Wit, Yasmin; Schärz, Noëlia; von Mierlo, Gerard; Angelillo-Scherrer, Anne; Brodard, Justine; Schefold, Joerg C.; Hirzel, Cédric; Jongerius, Ilse; Zeerleder, Sacha (2023). Immunothrombosis and complement activation contribute to disease severity and adverse outcome in COVID-19. Journal of innate immunity, 15(1), pp. 850-864. Karger 10.1159/000533339
Messerli, Christian; Wiedemann, Gertrud; Porret, Naomi; Nagler, Michael; Seipel, Katja; Jeker, Barbara; Novak, Urban; Zeerleder, Sacha; Bacher, Ulrike; Pabst, Thomas (2023). Correlation of peripheral chimeric antigen receptor T-cell (CAR-T cell) mRNA expression levels with toxicities and outcome in patients with diffuse large B-cell lymphoma (DLBCL). Turkish journal of haematology, 40(3), pp. 187-196. Turkish Society of Haematology 10.4274/tjh.galenos.2023.2023.0136
de Wit, Yasmin E S; Vlaar, Richard; Gouwerok, Eric; Hamzeh-Cognasse, Hind; van Mierlo, Gerard; Bulder, Ingrid; Lagerberg, Johan W M; de Korte, Dirk; Cognasse, Fabrice; Ten Brinke, Anja; Zeerleder, Sacha S (2023). Platelet concentrates in platelet additive solutions generate less complement activation products during storage than platelets stored in plasma. Blood transfusion, 21(2), pp. 157-167. SIMTI Servizi Srl 10.2450/2022.0323-21
de Boer, Esther Cw; Thielen, Astrid Jf; Langereis, Jeroen D; Kamp, Angela; Brouwer, Mieke C; Oskam, Nienke; Jongsma, Marlieke L; Baral, April J; Spaapen, Robbert M; Zeerleder, Sacha; Vidarsson, Gestur; Rispens, Theo; Wouters, Diana; Pouw, Richard B; Jongerius, Ilse (2023). The contribution of the alternative pathway in complement activation on cell surfaces depends on the strength of classical pathway initiation. Clinical & translational immunology, 12(1), e1436. Wiley 10.1002/cti2.1436
Rovó, Alicia; Gavillet, Mathilde; Drexler, Beatrice; Keller, Peter; Schneider, Jenny Sarah; Colucci, Giuseppe; Beauverd, Yan; van Dorland, Hendrika Anette; Pollak, Matthias; Schmidt, Adrian; De Gottardi, Andrea; Bissig, Marina; Lehmann, Thomas; Duchosal, Michel A; Zeerleder, Sacha (2023). Swiss Survey on current practices and opinions on clinical constellations triggering the search for PNH clones. Frontiers in medicine, 10(1200431), p. 1200431. Frontiers 10.3389/fmed.2023.1200431
Kroeze, Anna; Cornelissen, Anne S; Pascutti, M Fernanda; Verheij, Myrddin; Bulder, Ingrid; Klarenbeek, Sjoerd; Ait Soussan, Aicha; Hazenberg, Mette D; Nur, Erfan; van der Schoot, C Ellen; Voermans, Carlijn; Zeerleder, Sacha S (2022). Cell-free DNA levels are increased in acute graft-versus-host disease. European journal of haematology, 109(3), pp. 271-281. Wiley 10.1111/ejh.13806
de Wit, Yasmin E S; Hamzeh-Cognasse, Hind; Cognasse, Fabrice; Ten Brinke, Anja; Zeerleder, Sacha S (2022). DAMPS and complement activation in platelet concentrates that induce adverse reactions in patients. Transfusion, 62(9), pp. 1721-1726. Wiley-Blackwell 10.1111/trf.17061
Braschler, Thomas R; Zeerleder, Sacha (2022). [Immunglobulin Substitution Therapy in Hematological Patients with secondary Antibody Deficiency]. Therapeutische Umschau, 79(6), pp. 295-300. Hogrefe 10.1024/0040-5930/a001364
Heini, Alexander D; Bacher, Ulrike; Kronig, Marie-Noëlle; Wiedemann, Gertrud; Novak, Urban; Zeerleder, Sacha; Mansouri Taleghani, Behrouz; Daskalakis, Michael; Pabst, Thomas (2022). Chimeric antigen receptor T-cell therapy for relapsed mantle cell lymphoma: real-world experience from a single tertiary care center. Bone marrow transplantation, 57(6), pp. 1010-1012. Springer Nature 10.1038/s41409-022-01658-x
Kroeze, Anna; van Hoeven, Vera; Verheij, Myrddin W; Turksma, Annelies W; Weterings, Naomi; van Gassen, Sofie; Zeerleder, Sacha S; Blom, Bianca; Voermans, Carlijn; Hazenberg, Mette D (2022). Presence of innate lymphoid cells in allogeneic hematopoietic grafts correlates with reduced graft-versus-host disease. Cytotherapy, 24(3), pp. 302-310. Elsevier 10.1016/j.jcyt.2021.10.011
Wu, Linghe; Baylan, Umit; van der Leeden, Britt; Schurink, Bernadette; Roos, Eva; Schalkwijk, Casper G; Bugiani, Marianna; van der Valk, Paul; van Rossum, Albert C; Zeerleder, Sacha S.; Heunks, Leo M A; Boon, Reinier A; de Boer, Onno J; van der Wal, Allard C; Niessen, Hans W M; Krijnen, Paul A J (2022). Cardiac inflammation and microvascular procoagulant changes are decreased in second wave compared to first wave deceased COVID-19 patients. International journal of cardiology, 349, pp. 157-165. Elsevier 10.1016/j.ijcard.2021.11.079
Schenker, Carla; Hirzel, Cédric; Walti, Laura N.; Zeerleder, Sacha S.; Andres, Martin; Ramette, Alban; Barbani, Maria T.; Suter-Riniker, Franziska; Holbro, Andreas; Tritschler, Tobias (2022). Convalescent plasma and remdesivir for protracted COVID-19 in a patient with chronic lymphocytic leukaemia: a case report of late relapse after rapid initial response. British journal of haematology, 196(3), e27-e29. Wiley-Blackwell 10.1111/bjh.17806
Stanworth, Simon J; Brand, Anneke; Kaveri, Srini V; Vrielink, Hans; Greinacher, Andreas; Domanović, Dragoslav; von Lindern, Marieke; Allard, Shubha; Bayry, Jagadeesh; Bohonek, Milos; Buser, Andreas; Claas, Frans H J; Knutson, Folke; Lozano, Miguel; Olsson, Martin L; Pirenne, France; Rebulla, Paolo; So-Osman, Cynthia; Tissot, Jean-Daniel; Toye, Ashley M; ... (2022). The EHA Research Roadmap: Transfusion Medicine. HemaSphere, 6(2), e670. Wolters Kluwer Health 10.1097/HS9.0000000000000670
Delvasto, Laura; Roem, Dorina; Bakhtiari, Kamran; van Mierlo, Gerard J; Meijers, Joost; Jongerius, Ilse; Zeerleder, Sacha S (2022). Iron-driven alterations on red blood cell-derived microvesicles amplify coagulation during hemolysis via the intrinsic tenase complex. Thrombosis and haemostasis, 122(1), pp. 80-91. Thieme 10.1055/a-1497-9573
Holzer-Schär, Deborah Tabita; Daskalakis, Michael; Mansouri, Behrouz; Rovó, Alicia; Zeerleder, Sacha (2022). Thromboembolic complications in autoimmune hemolytic anemia. European journal of haematology, 108(1), pp. 45-51. Wiley-Blackwell 10.1111/ejh.13710
van Lier, Y F; Krabbendam, L; Haverkate, N J E; Zeerleder, S S; Rutten, C E; Blom, B; Spits, H; Hazenberg, M D (2022). GATA2 haploinsufficient patients lack innate lymphoid cells that arise after hematopoietic cell transplantation. Frontiers in immunology, 13, p. 1020590. Frontiers Research Foundation 10.3389/fimmu.2022.1020590
Jalink, M; de Boer, E C W; Evers, D; Havinga, M Q; Vos, J M I; Zeerleder, S; de Haas, M; Jongerius, I (2021). Halting targeted and collateral damage to red blood cells by the complement system. Seminars in immunopathology, 43(6), pp. 799-816. Springer-Verlag 10.1007/s00281-021-00859-8
Delvasto-Nuñez, Laura; Jongerius, Ilse; Zeerleder, Sacha (2021). It takes two to thrombosis: Hemolysis and complement. Blood reviews, 50, p. 100834. Elsevier 10.1016/j.blre.2021.100834
Verheij, Myrddin; Zeerleder, Sacha; Voermans, Carlijn (2021). Heme oxygenase-1: Equally important in allogeneic hematopoietic stem cell transplantation and organ transplantation? Transplant immunology, 68, p. 101419. Elsevier 10.1016/j.trim.2021.101419
Müller, Marcella C A; Dujardin, Romein W G; Thachil, Jecko; van Mierlo, Gerard; Zeerleder, Sacha S; Juffermans, Nicole P (2021). The relation between fibrinogen level, neutrophil activity and nucleosomes in the onset of disseminated intravascular coagulation in the critically ill. Journal of internal medicine, 290(4), pp. 922-927. Wiley 10.1111/joim.13346
Delvasto-Núñez, Laura; Roem, Dorina; Bakhtiari, Kamran; van Mierlo, Gerard; Meijers, Joost C M; Jongerius, Ilse; Zeerleder, Sacha S. (2021). Iron-Driven Alterations on Red Blood Cell-Derived Microvesicles Amplify Coagulation during Hemolysis via the Intrinsic Tenase Complex. (In Press). Thrombosis and haemostasis Thieme 10.1055/s-0041-1731051
van de Geer, Annemarie; Zandstra, Judith; Tanck, Michael W. T.; Nur, Efran; van Mierlo, Gerard; Jongerius, Ilse; van Bruggen, Robin; Zeerleder, Sacha S.; Kuijpers, Taco W. (2021). Biomarkers to predict infection and infection-related complications during chemotherapy-induced neutropenia in acute myeloid leukaemia: a pilot study. British journal of haematology, 193(5), pp. 1008-1012. Wiley-Blackwell 10.1111/bjh.17422
Capraru, Annina; Jalowiec, Katarzyna Aleksandra; Medri, Cesare; Daskalakis, Michael; Zeerleder, Sacha Sergio; Mansouri Taleghani, Behrouz (2021). Platelet Transfusion-Insights from Current Practice to Future Development. Journal of clinical medicine, 10(9) MDPI 10.3390/jcm10091990
Zeerleder, Sacha; Engel, Ruchira; Zhang, Tao; Roem, Dorina; van Mierlo, Gerard; Wagenaar-Bos, Ineke; van Ham, Sija Marieke; Wuhrer, Manfred; Wouters, Diana; Jongerius, Ilse (2021). Sugar Matters: Improving In Vivo Clearance Rate of Highly Glycosylated Recombinant Plasma Proteins for Therapeutic Use. Pharmaceuticals, 14(1) MDPI 10.3390/ph14010054
Jeker, Barbara; Daskalakis, Michael; Zeerleder, Sacha; Pabst, Thomas; Novak, Urban (January 2021). CAR T Cells: Immuntherapie mit grossem Potenzial. Onkologie & Hämatologie, 2021, pp. 16-19. Prime Public Media AG
Korkmaz, Halil Ibrahim; Ulrich, Magda M W; Wieringen, Wessel N Van; Doǧan, Hatice; Vlig, Marcel; Emmens, Reindert W; Meyer, Klaas W; Sinnige, Paul; Zeerleder, Sacha; Wouters, Diana; Ham, Marieke S Van; Zuijlen, Paul P M Van; Krijnen, Paul A J; Niessen, Hans W M (2021). C1 Inhibitor Administration Reduces Local Inflammation and Capillary Leakage, Without Affecting Long-term Wound Healing Parameters, in a Pig Burn Wound Model. Anti-inflammatory & anti-allergy agents in medicinal chemistry, 20(2), pp. 150-160. Bentham Science 10.2174/1871523019666200702101513
Nydegger, Anna; Novak, Urban; Kronig, Marie-Noëlle; Legros, Myriam; Zeerleder, Sacha; Banz, Yara; Bacher, Ulrike; Pabst, Thomas (2021). Transformed Lymphoma Is Associated with a Favorable Response to CAR-T-Cell Treatment in DLBCL Patients. Cancers, 13(23) MDPI AG 10.3390/cancers13236073
van Lier, Yannouck F; de Bree, Godelieve J; Jonkers, René E; Roelofs, Joris J T H; Ten Berge, Ineke J M; Rutten, Caroline E; Nur, Erfan; Kuijpers, Taco W; Hazenberg, Mette D; Zeerleder, Sacha S. (2020). Allogeneic hematopoietic cell transplantation in the management of GATA2 deficiency and pulmonary alveolar proteinosis. Clinical immunology, 218(108522), p. 108522. Elsevier 10.1016/j.clim.2020.108522
van Lier, Yannouck F; Davids, Mark; Haverkate, Nienke J E; de Groot, Pieter F; Donker, Marjolein L; Meijer, Ellen; Heubel-Moenen, Floor C J I; Nur, Erfan; Zeerleder, Sacha S.; Nieuwdorp, Max; Blom, Bianca; Hazenberg, Mette D (2020). Donor fecal microbiota transplantation ameliorates intestinal graft-versus-host disease in allogeneic hematopoietic cell transplant recipients. Science translational medicine, 12(556) American Association for the Advancement of Science 10.1126/scitranslmed.aaz8926
Pabst, Thomas; Joncourt, Raphael; Shumilov, Evgenii; Heini, Alexander; Wiedemann, Gertrud; Legros, Myriam; Seipel, Katja; Schild, Christof; Jalowiec, Katarzyna; Mansouri, Behrouz; Fux, Michaela; Novak, Urban; Porret, Naomi; Zeerleder, Sacha; Bacher, Vera (2020). Analysis of IL-6 serum levels and CAR-T cell specific digital PCR in the context of cytokine release syndrome (CRS). Experimental hematology, 88, 7-14.e3. Elsevier 10.1016/j.exphem.2020.07.003
Jäger, Ulrich; Barcellini, Wilma; Broome, Catherine M; Gertz, Morie A; Hill, Anita; Hill, Quentin A; Jilma, Bernd; Kuter, David J; Michel, Marc; Montillo, Marco; Röth, Alexander; Zeerleder, Sacha Sergio; Berentsen, Sigbjørn (2020). Diagnosis and treatment of autoimmune hemolytic anemia in adults: Recommendations from the First International Consensus Meeting. Blood reviews, 41, p. 100648. Elsevier 10.1016/j.blre.2019.100648
Yang, Jack; van Engelen, Tjitske S R; Haak, Bastiaan W; Bonta, Peter I; Majoor, Christof J; van 't Veer, Cornelis; de Vos, Alex F; Kemper, E Marleen; Lutter, René; van Mierlo, Gerard; Zeerleder, Sacha S.; Bel, Elisabeth H; van der Poll, Tom (2020). Effect of C1-inhibitor in adults with mild asthma: a randomised controlled trial. Allergy, 75(4), pp. 953-955. Wiley 10.1111/all.14053
d'Alessandro, Elisa; Becker, Christian; Bergmeier, Wolfgang; Bode, Christoph; Bourne, Joshua H; Brown, Helena; Buller, Harry R; Ten Cate-Hoek, Arina J; Ten Cate, Vincent; van Cauteren, Yvonne J M; Cheung, Yam F H; Cleuren, Audrey; Coenen, Danielle; Crijns, Harry J G M; de Simone, Ilaria; Dolleman, Sophie C; Klein, Christine Espinola; Fernandez, Delia I; Granneman, Lianne; van T Hof, Arnoud; ... (2020). Thrombo-Inflammation in Cardiovascular Disease: An Expert Consensus Document from the Third Maastricht Consensus Conference on Thrombosis. Thrombosis and haemostasis, 120(4), pp. 538-564. Thieme 10.1055/s-0040-1708035
Baas, Inge; Delvasto-Nuñez, Laura; Ligthart, Peter; Brouwer, Conny; Folman, Claudia; Reis, Edimara S; Ricklin, Daniel; Lambris, John D; Wouters, Diana; de Haas, Masja; Jongerius, Ilse; Zeerleder, Sacha S. (2020). Complement C3 inhibition by compstatin Cp40 prevents intra- and extravascular hemolysis of red blood cells. Haematologica - the hematology journal, 105(2), e57-e60. Ferrata-Storti Foundation 10.3324/haematol.2019.216028
Garcia Garrido, Hannah M; van Aalst, Mariëlle; Schinkel, Janke; Koen, Gerrit; Defoer, Jacqueline M; Hazenberg, Mette D; Nur, Erfan; Grobusch, Martin P; Zeerleder, Sacha S.; Goorhuis, Abraham; de Bree, Godelieve J (2019). Early loss of immunity against measles following allogeneic hematopoietic stem cell transplantation. American journal of hematology, 94(10), E270-E272. Wiley-Liss 10.1002/ajh.25590
Van Avondt, Kristof; Nur, Erfan; Zeerleder, Sacha Sergio (2019). Mechanisms of haemolysis-induced kidney injury. Nature reviews. Nephrology, 15(11), pp. 671-692. Nature Publishing Group 10.1038/s41581-019-0181-0
de Jong, Greta; Janssen, Jeroen J W M; Biemond, Bart J; Zeerleder, Sacha S.; Ossenkoppele, Gert J; Visser, Otto; Nur, Erfan; Meijer, Ellen; Hazenberg, Mette D (2019). Survival of early posthematopoietic stem cell transplantation relapse of myeloid malignancies. European journal of haematology, 103(5), pp. 491-499. Wiley-Blackwell 10.1111/ejh.13315
Heestermans, Marco; Salloum-Asfar, Salam; Streef, Tom; Laghmani, El Houari; Salvatori, Daniela; Luken, Brenda M; Zeerleder, Sacha S.; Spronk, Henri M H; Korporaal, Suzanne J; Kirchhofer, Daniel; Wagenaar, Gerry T M; Versteeg, Henri H; Reitsma, Pieter H; Renné, Thomas; van Vlijmen, Bart J M (2019). Mouse venous thrombosis upon silencing of anticoagulants depends on tissue factor and platelets, not FXII or neutrophils. Blood, 133(19), pp. 2090-2099. American Society of Hematology 10.1182/blood-2018-06-853762
Levi, Marcel; Cohn, Danny; Zeerleder, Sacha; Dziadzio, Magdalena; Longhurst, Hilary (2019). Long-term effects upon rituximab treatment of acquired angioedema due to C1-inhibitor deficiency. Allergy, 74(4), pp. 834-840. Wiley 10.1111/all.13686
van der Meer, Anne Jan; Ding, Chao; Hoogendijk, Arie Johan; de Vos, Alex F; Boon, Louis; Zeerleder, Sacha S.; van der Poll, Tom (2019). Neutrophils mitigate the systemic host response during endotoxemia in mice. Immunology, 156(3), pp. 277-281. Wiley-Blackwell 10.1111/imm.13026
Rijkers, Maaike; Schmidt, David; Lu, Nina; Kramer, Cynthia S M; Heidt, Sebastiaan; Mulder, Arend; Porcelijn, Leendert; Claas, Frans H J; Leebeek, Frank W G; Jansen, A J Gerard; Jongerius, Ilse; Zeerleder, Sacha S; Vidarsson, Gestur; Voorberg, Jan; de Haas, Masja (2019). Anti-HLA antibodies with complementary and synergistic interaction geometries promote classical complement activation on platelets. Haematologica - the hematology journal, 104(2), pp. 403-416. Ferrata-Storti Foundation 10.3324/haematol.2018.201665
Langedijk, Annefleur C; van Aalst, Mariëlle; Meek, Bob; van Leeuwen, Ester M M; Zeerleder, Sacha; Meijer, Ellen; Hazenberg, Mette D; Grobusch, Martin P; Goorhuis, Abraham (2019). Long-term pneumococcal vaccine immunogenicity following allogeneic hematopoietic stem cell transplantation. Vaccine, 37(3), pp. 510-515. Elsevier 10.1016/j.vaccine.2018.11.053
Engel, Ruchira; Delvasto-Nuñez, Laura; Roem, Dorina; van Mierlo, Gerard; Holst, Stephanie; Hipgrave Ederveen, Agnes L; van Buul, Jaap D; Wuhrer, Manfred; Wouters, Diana; Zeerleder, Sacha Sergio (2018). α1-Antichymotrypsin Present in Therapeutic C1-Inhibitor Products Competes with Selectin-Sialyl LewisX Interaction. Thrombosis and haemostasis, 118(12), pp. 2134-2144. Thieme 10.1055/s-0038-1675601
Thielen, Astrid J F; Meulenbroek, Elisabeth M; Baas, Inge; Bruggen, Robin; Zeerleder, Sacha S.; Wouters, Diana (2018). Complement Deposition and IgG Binding on Stored Red Blood Cells Are Independent of Storage Time. Transfusion medicine and hemotherapy, 45(6), pp. 378-384. Karger 10.1159/000486759
