FIB-4 Improves LSM-Based Prediction of Complications in Overweight or Obese Patients With Compensated Advanced Chronic Liver Disease.

Mendoza, Yuly P.; Shengir, Mohamed; Bosch, Jaime; Sebastiani, Giada; Berzigotti, Annalisa (2022). FIB-4 Improves LSM-Based Prediction of Complications in Overweight or Obese Patients With Compensated Advanced Chronic Liver Disease. Clinical gastroenterology and hepatology, 20(10), 2396-2398.e3. Elsevier 10.1016/j.cgh.2021.03.007

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Liver stiffness measurement (LSM) by transient elastography (TE) is able to stratify the risk of decompensation in patients with compensated advanced chronic liver disease (cACLD).1 Recently, we demonstrated that this holds true also in overweight or obese patients with cACLD due to nonalcoholic steatohepatitis (NASH) studied by the XL probe. An LSM cutoff of ≥21 kPa remained associated with a high risk of complications in this population.2.

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