Acute splanchnic vein thrombosis in patients with COVID-19: A systematic review.

Buso, Giacomo; Becchetti, Chiara; Berzigotti, Annalisa (2021). Acute splanchnic vein thrombosis in patients with COVID-19: A systematic review. Digestive and liver disease, 53(8), pp. 937-949. Elsevier 10.1016/j.dld.2021.05.021

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There is increasing evidence that coronavirus disease 2019 (COVID-19) is associated with a significant risk of venous thromboembolism. While information are mainly available for deep vein thrombosis of the lower limb and pulmonary embolism, scarce data exist regarding acute splanchnic vein thrombosis (SVT) in this setting. PubMed, EMBASE and Google Scholar English-language articles published up to 30 January 2021 on SVT in COVID-19 were searched. Overall, 21 articles reporting equal number of patients were identified. 15 subjects presented with portal vein thrombosis, 11 with mesenteric vein thrombosis, four with splenic vein thrombosis, and two with Budd-Chiari syndrome. Male sex was prevalent (15 patients), and median age was 43 years (range 26-79 years). Three patients had a history of liver disease, while no subject had known myeloproliferative syndrome. Clinical presentation included mainly gastrointestinal symptoms. Anticoagulation was started in 16 patients. Three patients underwent bowel resection. Ten subjects developed gastric or bowel ischemia, seven of whom underwent bowel resection, and four died after SVT diagnosis. Although rare, SVT should be seen as a complication of COVID-19. Patients with severe gastrointestinal symptoms should be screened for SVT, as rapid recognition and correct management are essential to improve the outcome of these patients.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Hepatologie
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Hepatologie

04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine
04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Hepatology

UniBE Contributor:

Becchetti, Chiara and Berzigotti, Annalisa

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1590-8658

Publisher:

Elsevier

Language:

English

Submitter:

Rahel Fuhrer

Date Deposited:

06 Jul 2021 14:44

Last Modified:

01 Aug 2021 01:35

Publisher DOI:

10.1016/j.dld.2021.05.021

PubMed ID:

34120860

Uncontrolled Keywords:

Anticoagulation Bowel ischemia Mesenteric vein thrombosis Portal vein thrombosis SARS-CoV-2

BORIS DOI:

10.48350/157399

URI:

https://boris.unibe.ch/id/eprint/157399

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