Mimicking a catabolic phenotype of intervertebral disc cells in 3D alginate culture

Bermudez Lekerika, Paola; Oberli, Andrea Elisabeth; Wuertz-Kosak, K.; Le Maitre, C. H.; Gantenbein, Benjamin (2021). Mimicking a catabolic phenotype of intervertebral disc cells in 3D alginate culture (Unpublished). In: 29th annual meeting of the European Orthopaedic Research Society. Rome, Italy. 14-18 September.

Introduction: Intervertebral Disc Degeneration (IDD) is a multifactorial pathological process often associated with chronic back pain. In the last decades a wide range of cytokines such as TNF-α or IL1-β have been applied in vitro to IVD cells to induce a catabolic phenotype to investigate the degenerative cascade. Hence, the aim of this study was to explore relevant catabolic phenotypes in-vitro in bovine intervertebral disc cells using 1.2% alginate beads as biological support after TNF-

Item Type:

Conference or Workshop Item (Poster)

Division/Institute:

04 Faculty of Medicine > Department of Orthopaedic, Plastic and Hand Surgery (DOPH) > Clinic of Orthopaedic Surgery

Graduate School:

Graduate School for Cellular and Biomedical Sciences (GCB)

UniBE Contributor:

Bermudez, Paola, Oberli, Andrea Elisabeth, Gantenbein, Benjamin

Subjects:

600 Technology > 610 Medicine & health

Language:

English

Submitter:

Benjamin Gantenbein

Date Deposited:

16 Nov 2021 16:20

Last Modified:

02 Mar 2023 23:35

URI:

https://boris.unibe.ch/id/eprint/160491

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