Cross-sectional study on the prevalence of influenza and pneumococcal vaccination and its association with health conditions and risk factors among hospitalized multimorbid older patients.

Papazoglou, Dimitrios David; Baretella, Oliver; Feller, Martin; Del Giovane, Cinzia; Moutzouri, Elisavet; Aujesky, Drahomir; Schwenkglenks, Matthias; O'Mahony, Denis; Knol, Wilma; Dalleur, Olivia; Rodondi, Nicolas; Baumgartner, Christine (2021). Cross-sectional study on the prevalence of influenza and pneumococcal vaccination and its association with health conditions and risk factors among hospitalized multimorbid older patients. PLoS ONE, 16(11), e0260112. Public Library of Science 10.1371/journal.pone.0260112

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BACKGROUND

Older adults with chronic conditions are at high risk of complications from influenza and pneumococcal infections. Evidence about factors associated with influenza and pneumococcal vaccination among older multimorbid persons in Europe is limited. The aim of this study was to investigate the prevalence and determinants of these vaccinations in this population.

METHODS

Multimorbid patients aged ≥70 years with polypharmacy were enrolled in 4 European centers in Switzerland, Belgium, the Netherlands, and Ireland. Data on vaccinations, demographics, health care contacts, and comorbidities were obtained from self-report, general practitioners and medical records. The association of comorbidities or medical contacts with vaccination status was assessed using multivariable adjusted log-binomial regression models.

RESULTS

Among 1956 participants with available influenza vaccination data (median age 79 years, 45% women), 1314 (67%) received an influenza vaccination within the last year. Of 1400 patients with available pneumococcal vaccination data (median age 79 years, 46% women), prevalence of pneumococcal vaccination was 21% (n = 291). The prevalence of vaccination remained low in high-risk populations with chronic respiratory disease (34%) or diabetes (24%), but increased with an increasing number of outpatient medical contacts. Chronic respiratory disease was independently associated with the receipt of both influenza and pneumococcal vaccinations (prevalence ratio [PR] 1.09, 95% confidence interval [CI] 1.03-1.16; and PR 2.03, 95%CI 1.22-3.40, respectively), as was diabetes (PR 1.06, 95%CI 1.03-1.08; PR 1.24, 95%CI 1.16-1.34, respectively). An independent association was found between number of general practitioner visits and higher prevalence of pneumococcal vaccination (p for linear trend <0.001).

CONCLUSION

Uptake of influenza and particularly of pneumococcal vaccination in this population of European multimorbid older inpatients remains insufficient and is determined by comorbidities and number and type of health care contacts, especially outpatient medical visits. Hospitalization may be an opportunity to promote vaccination, particularly targeting patients with few outpatient physician contacts.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Medical Education > Institute of General Practice and Primary Care (BIHAM)
04 Faculty of Medicine > Department of General Internal Medicine (DAIM) > Clinic of General Internal Medicine
04 Faculty of Medicine > Department of General Internal Medicine (DAIM) > Clinic of General Internal Medicine > Centre of Competence for General Internal Medicine

UniBE Contributor:

Papazoglou, Dimitrios David; Baretella, Oliver; Feller, Martin; Del Giovane, Cinzia; Moutzouri Beifuss, Elisavet; Aujesky, Drahomir; Rodondi, Nicolas and Baumgartner, Christine

Subjects:

600 Technology > 610 Medicine & health
300 Social sciences, sociology & anthropology > 360 Social problems & social services

ISSN:

1932-6203

Publisher:

Public Library of Science

Funders:

[201] Staatssekretariat für Bildung, Forschung und Innovation (SBFI) = Swiss State Secretariat for Education, Research and Innovation (SERI) ; [4] Swiss National Science Foundation

Language:

English

Submitter:

Christine Baumgartner

Date Deposited:

23 Nov 2021 12:07

Last Modified:

11 Dec 2021 09:02

Publisher DOI:

10.1371/journal.pone.0260112

PubMed ID:

34784405

BORIS DOI:

10.48350/161410

URI:

https://boris.unibe.ch/id/eprint/161410

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