Castro-Calderón, Adriana; Roccuzzo, Andrea; Ferrillo, Martina; Gada, Sneha; González-Serrano, José; Fonseca, Manrique; Molinero-Mourelle, Pedro (2022). Hyaluronic acid injection to restore the lost interproximal papilla: a systematic review. Acta odontologica scandinavica, 80(4), pp. 295-307. Informa Healthcare 10.1080/00016357.2021.2007282
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OBJECTIVES
To assess the efficacy and safety of hyaluronic acid (HA) injections to restore the lost interproximal papilla.
MATERIALS AND METHODS
A systematic literature search was conducted in PubMed/MEDLINE, Scopus and Cochrane electronic databases with no time restriction up to September 2021. Any clinical study evaluating HA injection into the interproximal papilla loss Class I and II according to Norland & Tarnow, were included based on the following PICO questions (1) Are HA injections effective for the reconstruction of the interproximal papilla loss? (2) What are the side/adverse effects of using HA for the reconstruction of interproximal papilla loss? The risk of bias assessment was performed using the Cochrane Collaboration's the Newcastle Ottawa and Joanna Briggs institute tools.
RESULTS
A total of 1497 titles were retrieved. From these, eleven were included and underwent full data extraction. However, due to heterogeneity in the data among the included articles, a meta-analysis could not be performed. Three articles reported no-differences in term of papilla tip to contact point distance or the papilla fill reduction. Finally, five studies showed a reduction in the black triangle with a percentage range between 19 and 47%.
CONCLUSION
The non-surgical use of HA injection seems to have a positive effect on the re-establishment of interproximal papilla lost. However post-operative complications might develop.
Item Type: |
Journal Article (Review Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > School of Dental Medicine > Department of Periodontology 04 Faculty of Medicine > School of Dental Medicine 04 Faculty of Medicine > School of Dental Medicine > Department of Reconstructive Dentistry and Gerodontology |
UniBE Contributor: |
Roccuzzo, Andrea, Gada, Sneha, Fonseca Escalante, Manrique, Molinero Mourelle, Pedro |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0001-6357 |
Publisher: |
Informa Healthcare |
Language: |
English |
Submitter: |
Lena Augé |
Date Deposited: |
22 Dec 2021 13:44 |
Last Modified: |
05 Dec 2022 15:55 |
Publisher DOI: |
10.1080/00016357.2021.2007282 |
PubMed ID: |
34855562 |
Uncontrolled Keywords: |
Hyaluronic acid interdental papilla non-surgical approach papilla reconstruction |
BORIS DOI: |
10.48350/161870 |
URI: |
https://boris.unibe.ch/id/eprint/161870 |
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