Genomic Data Reveal a Complex Making of Humans

Alves, Isabel; Srámková Hanulová, A.; Foll, Matthieu; Excoffier, Laurent (2012). Genomic Data Reveal a Complex Making of Humans. PLoS genetics, 8(7), e1002837. San Francisco, Calif.: Public Library of Science 10.1371/journal.pgen.1002837

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In the last few years, two paradigms underlying human evolution have crumbled. Modern humans have not totally replaced previous hominins without any admixture, and the expected signatures of adaptations to new environments are surprisingly lacking at the genomic level. Here we review current evidence about archaic admixture and lack of strong selective sweeps in humans. We underline the need to properly model differential admixture in various populations to correctly reconstruct past demography. We also stress the importance of taking into account the spatial dimension of human evolution, which proceeded by a series of range expansions that could have promoted both the introgression of archaic genes and background selection.

Item Type:

Journal Article (Original Article)

Division/Institute:

08 Faculty of Science > Department of Biology > Institute of Ecology and Evolution (IEE)
08 Faculty of Science > Department of Biology > Institute of Ecology and Evolution (IEE) > Population Genetics

UniBE Contributor:

Alves, Isabel; Sramkova Hanulova, Anna; Foll, Matthieu and Excoffier, Laurent

ISSN:

1553-7390

Publisher:

Public Library of Science

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:40

Last Modified:

27 Dec 2014 15:23

Publisher DOI:

10.1371/journal.pgen.1002837

Web of Science ID:

000306840400047

BORIS DOI:

10.7892/boris.16250

URI:

https://boris.unibe.ch/id/eprint/16250 (FactScience: 223851)

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