Development of an electronic Poor Outcome Screening (ePOS) Score to identify critically ill patients with potential palliative care needs.

Luethi, Nora; Wermelinger, Sarah D; Haynes, Alan G.; Roumet, Marie; Maessen, Maud; Affolter, Barbara; Müller, Martin; Schefold, Joerg; Eychmueller, Steffen; Cioccari, Luca (2022). Development of an electronic Poor Outcome Screening (ePOS) Score to identify critically ill patients with potential palliative care needs. Journal of critical care, 69, p. 154007. Elsevier 10.1016/j.jcrc.2022.154007

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PURPOSE

To develop and validate an electronic poor outcome screening (ePOS) score to identify critically ill patients with potentially unmet palliative care (PC) needs at 48 hours after ICU admission.

MATERIALS AND METHODS

Retrospective single-centre cohort study of 1'772 critically ill adult patients admitted to a tertiary academic ICU in Switzerland between 2017 and 2018. We used data available from electronic health records (EHR) in the first 48 hours and least absolute shrinkage and selection operator (LASSO) logistic regression to develop a prediction model and generate a score to predict the risk of all cause 6-month mortality.

RESULTS

Within 6 months of the ICU admission, 598 patients (33.7%) had died. At a cut-off of 20 points, the ePOS score (range 0-46 points) had a sensitivity of 0.81 (95% CI 0.78 to 0.84) and a specificity of 0.51 (0.48 to 0.54) for predicting 6-month mortality and showed good discriminatory performance (AUROC 0.72, 0.67 to 0.77).

CONCLUSIONS

The ePOS score can easily be implemented in EHR and can be used for automated screening and stratification of ICU patients, pinpointing those in whom a comprehensive PC assessment should be performed. However, it should not replace clinical judgement.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Intensive Care, Emergency Medicine and Anaesthesiology (DINA) > Clinic of Intensive Care
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Radiation Oncology
04 Faculty of Medicine > Department of Intensive Care, Emergency Medicine and Anaesthesiology (DINA) > University Emergency Center
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Medical Oncology
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Social and Preventive Medicine (ISPM)
04 Faculty of Medicine > Pre-clinic Human Medicine > Department of Clinical Research (DCR)

UniBE Contributor:

Lüthi, Nora, Haynes, Alan, Roumet, Marie Camille, Maessen, Maud, Affolter Baumberger, Barbara, Müller, Martin (B), Schefold, Jörg Christian, Eychmüller, Steffen, Cioccari, Luca (A)

Subjects:

600 Technology > 610 Medicine & health
300 Social sciences, sociology & anthropology > 360 Social problems & social services

ISSN:

0883-9441

Publisher:

Elsevier

Language:

English

Submitter:

Pubmed Import

Date Deposited:

21 Feb 2022 09:54

Last Modified:

20 Feb 2024 14:16

Publisher DOI:

10.1016/j.jcrc.2022.154007

PubMed ID:

35183039

Uncontrolled Keywords:

Intensive care end-of-life care mortality outcome palliative care prediction scores

BORIS DOI:

10.48350/165752

URI:

https://boris.unibe.ch/id/eprint/165752

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