Assessment of New Onset Arrhythmias After Transcatheter Aortic Valve Implantation Using an Implantable Cardiac Monitor.

Nozica, Nikolas; Siontis, George C M; Elchinova, Elena Georgieva; Goulouti, Eleni; Asami, Masahiko; Bartkowiak, Joanna; Baldinger, Samuel; Servatius, Helge; Seiler, Jens; Tanner, Hildegard; Noti, Fabian; Haeberlin, Andreas; Branca, Mattia; Lanz, Jonas; Stortecky, Stefan; Pilgrim, Thomas; Windecker, Stephan; Reichlin, Tobias; Praz, Fabien and Roten, Laurent (2022). Assessment of New Onset Arrhythmias After Transcatheter Aortic Valve Implantation Using an Implantable Cardiac Monitor. Frontiers in cardiovascular medicine, 9, p. 876546. Frontiers 10.3389/fcvm.2022.876546

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Transcatheter aortic valve implantation (TAVI) is associated with new onset brady- and tachyarrhythmias which may impact clinical outcome.


To investigate the true incidence of new onset arrhythmias within 12 months after TAVI using an implantable cardiac monitor (ICM).


One hundred patients undergoing TAVI received an ICM within 3 months before or up to 5 days after TAVI. Patients were followed-up for 12 months after discharge from TAVI for the occurrence of atrial fibrillation (AF), bradycardia (≤30 bpm), advanced atrioventricular (AV) block, sustained ventricular and supraventricular tachycardia.


A previously undiagnosed arrhythmia was observed in 31 patients (31%) and comprised AF in 19 patients (19%), advanced AV block in 3 patients (3%), and sustained supraventricular and ventricular tachycardia in 10 (10%) and 2 patients (2%), respectively. Three patients had a clinical diagnosis of sick-sinus-syndrome. A permanent pacemaker (PPM) was implanted in six patients (6%). The prevalence of pre-existing AF was 28%, and 47% of the patients had AF at the end of the study period. AF burden was significantly higher in patients with pre-existing [26.7% (IQR 0.3%; 100%)] compared to patients with new-onset AF [0.0% (IQR 0.0%; 0.06%); p = 0.001]. Three patients died after TAVI without evidence of an arrhythmic cause according to the available ICM recordings.


Rhythm monitoring for 12 months after TAVI revealed new arrhythmias, mainly AF, in almost one third of patients. Atrial fibrillation burden was higher in patients with prevalent compared to incident AF. Selected patients may benefit from short-term remote monitoring.

Trial Registration NCT02559011.

Item Type:

Journal Article (Original Article)


04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology
04 Faculty of Medicine > Pre-clinic Human Medicine > Department of Clinical Research (DCR)

UniBE Contributor:

Nozica, Nikolas, Siontis, Georgios, Elchinova, Elena Georgieva, Goulouti, Eleni, Bartkowiak, Joanna, Baldinger, Samuel Hannes, Servatius, Helge Simon (B), Seiler, Jens, Tanner, Hildegard, Noti, Fabian, Häberlin, Andreas David Heinrich, Branca, Mattia, Lanz, Jonas, Stortecky, Stefan, Pilgrim, Thomas, Windecker, Stephan, Reichlin, Tobias Roman, Praz, Fabien Daniel, Roten, Laurent


600 Technology > 610 Medicine & health






[4] Swiss National Science Foundation




Pubmed Import

Date Deposited:

03 Jun 2022 10:20

Last Modified:

20 Feb 2024 14:16

Publisher DOI:


PubMed ID:


Additional Information:

Praz and Roten contributed equally to this work.

Uncontrolled Keywords:

AV block TAVI atrial fibrillation bundle branch block (BBB) implantable cardiac monitor (ICM) pacemaker (PM) ventricular tachycardia (VT)




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