Dagilis, Andrius J; Sardell, Jason M; Josephson, Matthew P; Su, Yiheng; Kirkpatrick, Mark; Peichel, Catherine L (2022). Searching for signatures of sexually antagonistic selection on stickleback sex chromosomes. Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 377(1856), p. 20210205. Royal Society of London 10.1098/rstb.2021.0205
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Intralocus sexually antagonistic selection occurs when an allele is beneficial to one sex but detrimental to the other. This form of selection is thought to be key to the evolution of sex chromosomes but is hard to detect. Here we perform an analysis of phased young sex chromosomes to look for signals of sexually antagonistic selection in the Japan Sea stickleback (Gasterosteus nipponicus). Phasing allows us to date the suppression of recombination on the sex chromosome and provides unprecedented resolution to identify sexually antagonistic selection in the recombining region of the chromosome. We identify four windows with elevated divergence between the X and Y in the recombining region, all in or very near genes associated with phenotypes potentially under sexually antagonistic selection in humans. We are unable, however, to rule out the alternative hypothesis that the peaks of divergence result from demographic effects. Thus, although sexually antagonistic selection is a key hypothesis for the formation of supergenes on sex chromosomes, it remains challenging to detect. This article is part of the theme issue 'Genomic architecture of supergenes: causes and evolutionary consequences'.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
09 Interdisciplinary Units > Next Generation Sequencing (NGS) Platform 08 Faculty of Science > Department of Biology > Institute of Ecology and Evolution (IEE) > Evolutionary Ecology |
UniBE Contributor: |
Josephson, Matthew, Peichel, Catherine |
Subjects: |
500 Science > 570 Life sciences; biology |
ISSN: |
1471-2970 |
Publisher: |
Royal Society of London |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
14 Jun 2022 10:53 |
Last Modified: |
31 Dec 2022 07:05 |
Publisher DOI: |
10.1098/rstb.2021.0205 |
PubMed ID: |
35694749 |
Uncontrolled Keywords: |
Japan Sea stickleback sex chromosome evolution sexually antagonistic selection supergenes |
BORIS DOI: |
10.48350/170627 |
URI: |
https://boris.unibe.ch/id/eprint/170627 |
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