Karkampouna, Sofia; Kruithof-de Julio, Marianna; Thalmann, George N (2022). Role of prostate and bone stromal cells on prostate cancer progression. American journal of clinical and experimental urology, 10(3), pp. 180-187. e-Century Publishing
Full text not available from this repository.Prostate cancer is a highly heterogeneous disease, often manifesting in a metastatic form to the bone. Complex tumour cells and surrounding microenvironment interactions are important determinants of disease progression and therapy resistance. Here, we provide an overview of some of the early studies that recognized the pro-tumourigenic role of prostate stroma, particularly fibroblasts, bone stromal components, and its permissive tumour properties. This article is written in memory of Prof. Dr LWK Chung and his contributions. Prostate and bone metastasis stroma concepts emerging from his work are now more actively being pursued by the authors of this article and others in the field.
Item Type: |
Journal Article (Review Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Urologie 04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Urologie 04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Urology |
UniBE Contributor: |
Karkampouna, Sofia, Kruithof-de Julio, Marianna, Thalmann, George |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
2330-1910 |
Publisher: |
e-Century Publishing |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
26 Jul 2022 13:02 |
Last Modified: |
05 Dec 2022 16:22 |
PubMed ID: |
35874291 |
Uncontrolled Keywords: |
LNCaP Prostate cancer bone metastasis organoids stroma tumour microenvironment |
URI: |
https://boris.unibe.ch/id/eprint/171538 |
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