Influence of Lung Reconstruction Algorithms on Interstitial Lung Pattern Recognition on CT.

Klaus, Jeremias B; Christodoulidis, Stergios; Peters, Alan A; Hourscht, Cynthia; Loebelenz, Laura I; Munz, Jaro; Schroeder, Christophe; Sieron, Dominik; Drakopoulos, Dionysios; Stadler, Severin; Heverhagen, Johannes T; Prosch, Helmut; Huber, Adrian; Pohl, Moritz; Mougiakakou, Stavroula G; Christe, Andreas; Ebner, Lukas (2022). Influence of Lung Reconstruction Algorithms on Interstitial Lung Pattern Recognition on CT. (In Press). RöFo. Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren Thieme 10.1055/a-1901-7814

[img]
Preview
Text
a-1901-7814.pdf - Published Version
Available under License Creative Commons: Attribution-Noncommercial-No Derivative Works (CC-BY-NC-ND).

Download (774kB) | Preview

BACKGROUND

Despite current recommendations, there is no recent scientific study comparing the influence of CT reconstruction kernels on lung pattern recognition in interstitial lung disease (ILD).

PURPOSE

To evaluate the sensitivity of lung (i70) and soft (i30) CT kernel algorithms for the diagnosis of ILD patterns.

MATERIALS AND METHODS

We retrospectively extracted between 15-25 pattern annotations per case (1 annotation = 15 slices of 1 mm) from 23 subjects resulting in 408 annotation stacks per lung kernel and soft kernel reconstructions. Two subspecialized chest radiologists defined the ground truth in consensus. 4 residents, 2 fellows, and 2 general consultants in radiology with 3 to 13 years of experience in chest imaging performed a blinded readout. In order to account for data clustering, a generalized linear mixed model (GLMM) with random intercept for reader and nested for patient and image and a kernel/experience interaction term was used to analyze the results.

RESULTS

The results of the GLMM indicated, that the odds of correct pattern recognition is 12 % lower with lung kernel compared to soft kernel; however, this was not statistically significant (OR 0.88; 95%-CI, 0.73-1.06; p = 0.187). Furthermore, the consultants' odds of correct pattern recognition was 78 % higher than the residents' odds, although this finding did not reach statistical significance either (OR 1.78; 95%-CI, 0.62-5.06; p = 0.283). There was no significant interaction between the two fixed terms kernel and experience. Intra-rater agreement between lung and soft kernel was substantial (κ = 0.63 ± 0.19). The mean inter-rater agreement for lung/soft kernel was κ = 0.37 ± 0.17/κ = 0.38 ± 0.17.

CONCLUSION

There is no significant difference between lung and soft kernel reconstructed CT images for the correct pattern recognition in ILD. There are non-significant trends indicating that the use of soft kernels and a higher level of experience lead to a higher probability of correct pattern identification.

KEY POINTS

· There is no significant difference between lung and soft kernel reconstructed CT images for the correct pattern recognition in interstitial lung disease.. · There are even non-significant tendencies that the use of soft kernels lead to a higher probability of correct pattern identification.. · These results challenge the current recommendations and the routinely performed separate lung kernel reconstructions for lung parenchyma analysis..

CITATION FORMAT

· Klaus JB, Christodoulidis S, Peters AA et al. Influence of Lung Reconstruction Algorithms on Interstitial Lung Pattern Recognition on CT. Fortschr Röntgenstr 2022; DOI: 10.1055/a-1901-7814.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic, Interventional and Paediatric Radiology
10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research
04 Faculty of Medicine > Service Sector > Institute of Legal Medicine > Forensic Medicine

UniBE Contributor:

Klaus, Jeremias Bendicht; Christodoulidis, Stergios; Peters, Alan Arthur; Hourscht, Cynthia; Löbelenz, Laura Isabel; Munz, Jaro Manuele; Schroeder, Christophe; Sieron, Dominik Aleksander; Drakopoulos, Dionysios; Heverhagen, Johannes; Huber, Adrian Thomas; Mougiakakou, Stavroula; Christe, Andreas and Ebner, Lukas

Subjects:

600 Technology > 610 Medicine & health
500 Science > 570 Life sciences; biology
300 Social sciences, sociology & anthropology > 360 Social problems & social services

ISSN:

1438-9029

Publisher:

Thieme

Language:

English

Submitter:

Pubmed Import

Date Deposited:

08 Sep 2022 07:41

Last Modified:

08 Sep 2022 07:41

Publisher DOI:

10.1055/a-1901-7814

PubMed ID:

36067777

BORIS DOI:

10.48350/172706

URI:

https://boris.unibe.ch/id/eprint/172706

Actions (login required)

Edit item Edit item
Provide Feedback