Weil-Verhoeven, Delphine; Di Martino, Vincent; Stirnimann, Guido; Cervoni, Jean Paul; Nguyen-Khac, Eric; Thévenot, Thierry (2022). Alfapump® implantable device in management of refractory ascites: An update. World journal of hepatology, 14(7), pp. 1344-1356. Baishideng Publishing Group Inc 10.4254/wjh.v14.i7.1344
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Refractory ascites (RA) is a frequent and life-threatening complication of cirrhosis. In selected patients with RA, transjugular intrahepatic portosystemic shunt (TIPS) placement and liver transplantation (LT) are currently considered the best therapeutic alternatives to repeated large volume paracentesis. In patients with a contraindication to TIPS or LT, the alfapump® system (Sequana Medical, Ghent, Belgium) has been developed to reduce the need for iterative paracentesis, and consequently to improve the quality of life and nutritional status. We report here recent data on technical progress made since the first implantation, the efficacy and tolerance of the device, the position of the pump in the therapeutic arsenal for refractory ascites, and the grey areas that remain to be clarified regarding the optimal selection of patients who are potential candidates for this treatment.
Item Type: |
Journal Article (Review Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Hepatology |
UniBE Contributor: |
Stirnimann, Guido |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1948-5182 |
Publisher: |
Baishideng Publishing Group Inc |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
29 Sep 2022 08:11 |
Last Modified: |
05 Dec 2022 16:25 |
Publisher DOI: |
10.4254/wjh.v14.i7.1344 |
PubMed ID: |
36158913 |
Uncontrolled Keywords: |
Alfapump Automated low flow ascites pump Cirrhosis Liver Refractory ascites |
BORIS DOI: |
10.48350/173363 |
URI: |
https://boris.unibe.ch/id/eprint/173363 |