Loss of the volume-regulated anion channel components LRRC8A and LRRC8D limits platinum drug efficacy

Widmer, Carmen A; Klebic, Ismar; Domanitskaya, Natalya; Decollogny, Morgane Francine; Howald, Denise; Siffert, Myriam; Essers, Paul; Nowicka, Zuzanna; Stokar-Regenscheit, Nadine; van de Ven, Marieke; de Korte-Grimmerink, Renske; Galván, José A; Pritchard, Colin E.J.; Huijbers, Ivo J; Fendler, Wojciech; Vens, Conchita; Rottenberg, Sven (2022). Loss of the volume-regulated anion channel components LRRC8A and LRRC8D limits platinum drug efficacy. Cancer research communications, 2(10), pp. 1266-1281. American Association for Cancer Research 10.1158/2767-9764.CRC-22-0208

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Item Type:

 Journal Article (Original Article)

Division/Institute:

 05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Animal Pathology
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP)
04 Faculty of Medicine > Faculty Institutions > Bern Center for Precision Medicine (BCPM)
09 Interdisciplinary Units > Microscopy Imaging Center (MIC)

Graduate School:

 Graduate School for Cellular and Biomedical Sciences (GCB)

UniBE Contributor:

 Widmer, Carmen, Klebic, Ismar, Decollogny, Morgane Francine, Howald, Denise, Siffert, Myriam, Rottenberg, Sven

Subjects:

 600 Technology > 630 Agriculture

ISSN:

 2767-9764

Publisher:

 American Association for Cancer Research

Funders:

 Organisations 310030 not found.; Organisations 883877 not found.

Language:

 English

Submitter:

 Andrea Stettler

Date Deposited:

 04 Oct 2022 12:42

Last Modified:

 02 Mar 2023 23:36

Publisher DOI:

 10.1158/2767-9764.CRC-22-0208

Uncontrolled Keywords:

 VRAC, LRRC8A, LRRC8D, Platinum drug resistance, BRCA1, high-dose chemotherapy, genetically engineered mouse model, breast cancer, HNSCC

BORIS DOI:

 10.48350/173489

URI:

 https://boris.unibe.ch/id/eprint/173489

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