In vitro induction of catabolic response to intervertebral disc cells in 3D culture.

Bermudez, P.; Croft, A. S.; Crump, K. B.; Wuertz-Kosak, K.; Le Maitre, C. L.; Gantenbein, B. (2022). In vitro induction of catabolic response to intervertebral disc cells in 3D culture. European cells & materials eCM. University of Wales

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INTRODUCTION: Intervertebral disc (IVD) degeneration is considered a key contributor for low back pain, which is the leading cause of disability worldwide1. In the last decades, a wide range of cytokines have been applied to IVD cells in-vitro to investigate the degenerative cascade2,3. However, a generic stimulation model defining dose and duration is lacking. Hence, we aimed to explore the catabolic response of bovine IVD cells after TNF-

Item Type:

Conference or Workshop Item (Poster)

Division/Institute:

04 Faculty of Medicine > Department of Orthopaedic, Plastic and Hand Surgery (DOPH) > Clinic of Orthopaedic Surgery

Graduate School:

Graduate School for Cellular and Biomedical Sciences (GCB)

UniBE Contributor:

Bermudez, Paola, Croft, Andreas Shaun, Crump, Katherine Briana, Gantenbein, Benjamin

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1473-2262

Publisher:

University of Wales

Language:

English

Submitter:

Benjamin Gantenbein

Date Deposited:

12 Dec 2022 15:11

Last Modified:

12 Dec 2022 18:39

Additional Information:

9th June, Zürich Switzerland

BORIS DOI:

10.48350/175708

URI:

https://boris.unibe.ch/id/eprint/175708

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