Is liposomal bupivacaine superior to standard bupivacaine for pain control following minimally invasive thoracic surgery?

Zhang, Yang; Zhao, Liang; Li, Shuangjiang; Liu, Junhua (2020). Is liposomal bupivacaine superior to standard bupivacaine for pain control following minimally invasive thoracic surgery? Interactive cardiovascular and thoracic surgery, 31(2), pp. 199-203. Oxford University Press 10.1093/icvts/ivaa083

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A best evidence topic in thoracic surgery was written according to a structured protocol. The question addressed was whether regional liposomal bupivacaine was superior to standard bupivacaine for pain control following minimally invasive thoracic surgery. Altogether 70 papers were found using the reported search, of which 5 papers represented the best evidence to answer the clinical question. The authors, journal, date and country of publication, patient group studied, study type, relevant outcomes and results of these papers are tabulated. Two of the five available studies showed a significant reduction of early narcotic consumption with the regional analgesia using liposomal bupivacaine, one showed a significantly reduced usage of opioid medication during postoperative hour 24-36 among the patients receiving liposomal bupivacaine, and 2 showed no difference in cumulative opioid consumption between the 2 regional analgesia groups. In addition, there was no associated difference in the pain severity scores or the length of hospitalization.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Thoracic Surgery
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > Forschungsbereich Mu50 > Forschungsgruppe Thoraxchirurgie

Graduate School:

Graduate School for Cellular and Biomedical Sciences (GCB)

UniBE Contributor:

Yang, Zhang (A), Zhao, Liang, Li, Shuangjiang

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1569-9293

Publisher:

Oxford University Press

Language:

English

Submitter:

Thomas Michael Marti

Date Deposited:

16 Dec 2022 14:59

Last Modified:

16 Dec 2022 18:38

Publisher DOI:

10.1093/icvts/ivaa083

PubMed ID:

32530037

Uncontrolled Keywords:

Liposomal bupivacaine Minimally invasive surgery Pain control Thoracic surgery

BORIS DOI:

10.48350/175986

URI:

https://boris.unibe.ch/id/eprint/175986

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