Angata, Takashi; von Gunten, Stephan; Schnaar, Ronald L.; Varki, Ajit (2022). I-Type Lectins. In: Essentials of Glycobiology. Cold Spring Harbor Laboratory Press 10.1101/glycobiology.4e.35
|
Text
von_Gunten__I-type_lectins.pdf - Published Version Available under License Creative Commons: Attribution-Noncommercial-No Derivative Works (CC-BY-NC-ND). Download (1MB) | Preview |
I-type lectins are defined as glycan-binding proteins (excluding antibodies and T-cell receptors) in which the binding domain is homologous to the large and varied immunoglobulin superfamily (IgSF) of proteins. Among I-type lectins, the Siglec family of sialic acid–recognizing lectins is the best characterized subgroup, both structurally and functionally, and is therefore the major focus of this chapter. Details of their discovery, characterization, binding properties, and biology are provided, along with discussions of their functional roles in vertebrate biology, with most currently available information being in mammals, and multiple unusual changes during human evolution.
Item Type: |
Book Section (Review Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Pharmacology |
UniBE Contributor: |
von Gunten, Stephan |
Subjects: |
600 Technology > 610 Medicine & health |
Publisher: |
Cold Spring Harbor Laboratory Press |
Language: |
English |
Submitter: |
Celine Joray |
Date Deposited: |
05 Jan 2023 16:10 |
Last Modified: |
30 May 2023 14:23 |
Publisher DOI: |
10.1101/glycobiology.4e.35 |
PubMed ID: |
35536967 |
Additional Information: |
Chapter 35 |
BORIS DOI: |
10.48350/176779 |
URI: |
https://boris.unibe.ch/id/eprint/176779 |
Actions (login required)
 |
Edit item |