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Mathis, Déborah; du Toit, Therina; Altinkilic, Emre Murat; Stojkov, Darko; Urzì, Christian; Voegel, Clarissa D; Wu, Vincen; Zamboni, Nicola; Simon, Hans-Uwe; Nuoffer, Jean-Marc; Flück, Christa E; Felser, Andrea (2024). Mitochondrial dysfunction results in enhanced adrenal androgen production in H295R cells. The journal of steroid biochemistry and molecular biology, 243(106561), p. 106561. Elsevier 10.1016/j.jsbmb.2024.106561
Traidl-Hoffmann, Claudia; Afghani, Jamie; Akdis, Cezmi; Akdis, Mübecel; Aydin, Handan; Bärenfaller, Katja; Behrendt, Heidrun; Bieber, Thomas; Bigliardi, Paul; Bigliardi-Qi, Mei; Bonefeld, Charlotte Menné; Bösch, Stefanie; Brüggen, Marie Charlotte; Diemert, Sebastian; Duchna, Hans-Werner; Fähndrich, Martina; Fehr, Danielle; Fellmann, Marc; Frei, Remo; Garvey, Lena H; ... (2024). Navigating the evolving landscape of atopic dermatitis: Challenges and future opportunities: The 4th Davos declaration. Allergy, 79(10), pp. 2605-2624. Wiley 10.1111/all.16247
Karimova, Adelya F; Ketkar, Avanee; Suezov, Roman; Khalitova, Adelya R; Gomzikova, Marina; Mukhamedshina, Yana; Lauth, Matthias; Huber, Magdalena; Simon, Hans-Uwe; Brichkina, Anna (2024). In vitro functional assays to assess the reciprocal interplay between tumor cells and macrophages. FASEB journal, 38(13) Federation of American Societies for Experimental Biology 10.1096/fj.202400240R
Godat, Anne; Mueller, Ralph; Schenker, Désirée; Schoepfer, Alain M; Straumann, Alex; Greuter, Thomas (2024). Eosinophil Distribution in Eosinophilic Esophagitis and its Impact on Disease Activity and Response to Treatment. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 22(7), 1528-1530.e3. 10.1016/j.cgh.2023.12.003
Sharapova, Gulnaz; Sabirova, Sirina; Gomzikova, Marina; Brichkina, Anna; Barlev, Nick A; Kalacheva, Natalia V; Rizvanov, Albert; Markov, Nikita; Simon, Hans-Uwe (2024). Mitochondrial Protein Density, Biomass, and Bioenergetics as Predictors for the Efficacy of Glioma Treatments. International journal of molecular sciences, 25(13) MDPI 10.3390/ijms25137038
Ueki, Yasushi; Häner, Jonas; Losdat, Sylvain; Gargiulo, Giuseppe; Shibutani, Hiroki; Bär, Sarah; Otsuka, Tatsuhiko; Kavaliauskaite, Raminta; Mitter, Vera; Temperli, Fabrice; Spirk, David; Stortecky, Stefan; Siontis, George; Valgimigli, Marco; Windecker, Stephan; Gutmann, Clemens; Koskinas, Konstantinos C; Mayr, Manuel; Raber, Lorenz (2024). Effect of Alirocumab Added to High-Intensity Statin on Platelet Reactivity and Non-coding RNAs in AMI Patients: A Substudy of the PACMAN-AMI Trial. Thrombosis and haemostasis, 124(6), pp. 517-527. Thieme 10.1055/a-2156-7872
Chen, Xin; Tsvetkov, Andrey S; Shen, Han-Ming; Isidoro, Ciro; Ktistakis, Nicholas T; Linkermann, Andreas; Koopman, Werner J H; Simon, Hans-Uwe; Galluzzi, Lorenzo; Luo, Shouqing; Xu, Daqian; Gu, Wei; Peulen, Olivier; Cai, Qian; Rubinsztein, David C; Chi, Jen-Tsan; Zhang, Donna D; Li, Changfeng; Toyokuni, Shinya; Liu, Jinbao; ... (2024). International consensus guidelines for the definition, detection, and interpretation of autophagy-dependent ferroptosis. Autophagy, 20(6), pp. 1213-1246. Taylor & Francis 10.1080/15548627.2024.2319901
Grünert, Sarah C; Gautschi, Matthias; Baker, Joshua; Boyer, Monica; Burlina, Alberto; Casswall, Thomas; Corpeleijn, Willemijn; Çıki, Kismet; Cotter, Melanie; Crushell, Ellen; Derks, Terry G J; Haas, Dorothea; Kilavuz, Sebile; Kingma, Sandra D K; Korman, Stanley H; Kozek, Anne; de Laet, Corinne; Mundy, Helen; Nassogne, Marie Cecile; Quintero, Victor; ... (2024). Empagliflozin for treating neutropenia and neutrophil dysfunction in 21 infants with glycogen storage disease 1b. Molecular genetics and metabolism, 142(2), p. 108486. Elsevier 10.1016/j.ymgme.2024.108486
Rexhaj, Emrush; Bär, Sarah; Soria, Rodrigo; Ueki, Yasushi; Häner, Jonas D; Otsuka, Tatsuhiko; Kavaliauskaite, Raminta; Siontis, George CM; Stortecky, Stefan; Shibutani, Hiroki; Spirk, David; Engstrøm, Thomas; Lang, Irene; Morf, Laura; Ambühl, Maria; Windecker, Stephan; Losdat, Sylvain; Koskinas, Konstantinos C; Räber, Lorenz (2024). Effects of alirocumab on endothelial function and coronary atherosclerosis in myocardial infarction: A PACMAN-AMI randomized clinical trial substudy. Atherosclerosis, 392, p. 117504. Elsevier 10.1016/j.atherosclerosis.2024.117504
Sebastian, Tim; Barco, Stefano; Voci, Davide; Lichtenberg, Michael; Schlager, Oliver; Jalaie, Houman; de Graaf, Rick; Erbel, Christian; Massmann, Alexander; Schindewolf, Marc; Spirk, David (2024). The TOPOS study. Vasa - European journal of vascular medicine, 53(3), pp. 217-224. Huber 10.1024/0301-1526/a001118
Gigon, Lea; Müller, Philipp; Haenni, Beat; Iacovache, Ioan; Barbo, Maruša; Gosheva, Gordana; Yousefi, Shida; Soragni, Alice; von Ballmoos, Christoph; Zuber, Benoît; Simon, Hans-Uwe (2024). Membrane damage by MBP-1 is mediated by pore formation and amplified by mtDNA. Cell reports, 43(4), p. 114084. Cell Press 10.1016/j.celrep.2024.114084
Rafiq, Sreoshee; Mungure, Irene; Banz, Yara; Niklaus, Nicolas J.; Kaufmann, Thomas; Müller, Stefan; Jacquel, Arnaud; Robert, Guillaume; Auberger, Patrick; Torbett, Bruce E; Muller, Sylviane; Tschan, Mario P.; Humbert, Magali (2024). HSPA8 Chaperone Complex Drives Chaperone-Mediated Autophagy Regulation in Acute Promyelocytic Leukemia Cell Differentiation. Pharmacology, 109(4), pp. 216-230. Karger 10.1159/000537864
Greuter, Thomas; Straumann, Alex; Fernández Marrero, Yuniel; Germic, Nina; Hosseini, Aref; Chanwangpong, Apinya; Yousefi, Shida; Simon, Dagmar; Collins, Margaret H; Bussmann, Christian; Chehade, Mirna; Dellon, Evan S; Furuta, Glenn T; Gonsalves, Nirmala; Hirano, Ikuo; Moawad, Fouad J; Biedermann, Luc; Safroneeva, Ekaterina; Schoepfer, Alain M and Simon, Hans-Uwe (2024). A Multicenter Long-Term Cohort Study of Eosinophilic Esophagitis Variants and Their Progression to EOE over Time. Clinical and translational gastroenterology, 15(4), e00664. Wolters Kluwer Health 10.14309/ctg.0000000000000664
Thormann, Kathrin; Lüthi, Anne-Sophie; Deniau, Felix; Heider, Anja; Cazzaniga, Simone; Radonjic-Hoesli, Susanne; Lehmann, Mathias; Schlapbach, Christoph; Herzog, Elio L; Kreuzer, Marco; Zinkernagel, Martin S; Akdis, Cezmi A; Zysset, Denise C; Simon, Hans-Uwe; Simon, Dagmar (2024). Dupilumab-associated ocular surface disease is characterized by a shift from Th2/Th17 toward Th1/Th17 inflammation. Allergy, 79(4), pp. 937-948. Wiley-Blackwell 10.1111/all.16045
Melino, Gerry; Knight, Richard A; Mak, Tak Wah; Piacentini, Mauro; Simon, Hans-Uwe; Shi, Yufang (2024). The birth of death, 30 years ago. Cell death and differentiation, 31(4), pp. 379-386. Nature Publishing Group 10.1038/s41418-024-01276-8
Mehta, Akul Y; Tilton, Catherine A; Muerner, Lukas; Gunten, Stephan; Heimburg-Molinaro, Jamie; Cummings, Richard D (2024). Reusable glycan microarrays using a microwave assisted wet-erase (MAWE) process. Glycobiology, 34(2) Oxford University Press 10.1093/glycob/cwad091
Chen, Yihe; Markov, Nikita; Gigon, Lea; Hosseini, Aref; Yousefi, Shida; Stojkov, Darko; Simon, Hans-Uwe (2024). The BK Channel Limits the Pro-Inflammatory Activity of Macrophages. Cells, 13(4) MDPI 10.3390/cells13040322
Gragnano, Felice; Calabrò, Paolo; Mehran, Roxana; Valgimigli, Marco (2024). Reply: Unconvinced by Data or Resistance to Change? Journal of the American College of Cardiology, 83(1), e11-e12. Elsevier 10.1016/j.jacc.2023.10.027
Stojkov, Darko; Yousefi, Shida; Simon, Hans-Uwe (2024). NETs: Important players in asthma? Journal of allergy and clinical immunology, 153(1), pp. 100-102. Elsevier 10.1016/j.jaci.2023.09.031
Heil, Alexis; Kuehlewindt, Tobias; Godat, Anne; Simon, Hans-Uwe; Simon, Dagmar; Schreiner, Philipp; Saner, Catherine; Vavricka, Stephan R; Biedermann, Luc; Safroneeva, Ekaterina; Rossel, Jean-Benoît; Limacher, Andreas; Straumann, Alex; Schoepfer, Alain M; Greuter, Thomas (2024). Histological Phenotyping in Eosinophilic Esophagitis: Localized Proximal Disease Is Infrequent but Associated with Less Severe Disease and Better Disease Outcome. International archives of allergy and immunology, 185(1), pp. 63-72. Karger 10.1159/000533815
Lambrecht, Rebekka; Rudolf, Franziska; Ückert, Anna-Katharina; Sladky, Valentina C; Phan, Truong San; Jansen, Jasmin; Naim, Samara; Kaufmann, Thomas; Keogh, Adrian; Kirschnek, Susanne; Mangerich, Aswin; Stengel, Florian; Leist, Marcel; Villunger, Andreas; Brunner, Thomas (2024). Non-canonical BIM-regulated energy metabolism determines drug-induced liver necrosis. Cell death and differentiation, 31(1), pp. 119-131. Nature Publishing Group 10.1038/s41418-023-01245-7
Manaila, Roxana-Cristiana; Huwiler, Andrea (2024). [Polypharmacy in acute and chronic kidney diseases]. Innere Medizin, 65(1), pp. 22-28. Springer 10.1007/s00108-023-01634-7
Bachmeier-Zbären, Noemi; Kinet, Jean-Pierre; Kaufmann, Thomas; Eggel, Alexander (2024). Mast cell activation test. In: Reference Module in Food Science (pp. 579-589). Elsevier 10.1016/B978-0-323-96018-2.00032-8
Bürgler, Christina; Dutoit, Danielle; Radonjic-Hoesli, Susanne; Thormann, Kathrin; Lehmann, Mathias; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (2024). Dupilumab normalizes correlates of lysosomal function in atopic dermatitis. JEADV Clinical Practice, 3(2), pp. 478-486. Wiley 10.1002/jvc2.307
Manda-Handzlik, Aneta; Stojkov, Darko; Wachowska, Malgorzata; Surmiak, Marcin (2024). Editorial: Neutrophil extracellular traps: mechanistic and functional insight. Frontiers in immunology, 15(1407232) Frontiers Research Foundation 10.3389/fimmu.2024.1407232
Gorog, Diana A; Ferreiro, Jose Luis; Ahrens, Ingo; Ako, Junya; Geisler, Tobias; Halvorsen, Sigrun; Huber, Kurt; Jeong, Young-Hoon; Navarese, Eliano P; Rubboli, Andrea; Sibbing, Dirk; Siller-Matula, Jolanta M; Storey, Robert F; Tan, Jack W C; Ten Berg, Jurrien M; Valgimigli, Marco; Vandenbriele, Christophe; Lip, Gregory Y H (2023). De-escalation or abbreviation of dual antiplatelet therapy in acute coronary syndromes and percutaneous coronary intervention: a Consensus Statement from an international expert panel on coronary thrombosis. Nature reviews. Cardiology, 20(12), pp. 830-844. Nature Publishing Group 10.1038/s41569-023-00901-2
Jesenak, Milos; Diamant, Zuzana; Simon, Dagmar; Tufvesson, Ellen; Seys, Sven F; Mukherjee, Manali; Lacy, Paige; Vijverberg, Susanne; Slisz, Tomas; Sediva, Anna; Simon, Hans-Uwe; Striz, Ilja; Plevkova, Jana; Schwarze, Jurgen; Kosturiak, Radovan; Alexis, Neil E; Untersmayr, Eva; Vasakova, Martina Koziar; Knol, Edward and Koenderman, Leo (2023). Eosinophils-from cradle to grave: An EAACI task force paper on new molecular insights and clinical functions of eosinophils and the clinical effects of targeted eosinophil depletion. Allergy, 78(12), pp. 3077-3102. Wiley 10.1111/all.15884
Deng, Haibin; Ge, Huixiang; Dubey, Christelle; Losmanova, Tereza; Medova, Michaela; Konstantinidou, Georgia; Mutlu, Seyran Mathilde; Birrer, Fabienne Esther; Brodie, Tess Melinda; Stroka, Deborah; Wang, Wenxiang; Peng, Ren-Wang; Dorn, Patrick; Marti, Thomas Michael (2023). An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer immunology, immunotherapy : CII, 72(12), pp. 4457-4470. Springer 10.1007/s00262-023-03542-z
Shuvalov, Oleg; Kirdeeva, Yulia; Daks, Alexandra; Fedorova, Olga; Parfenyev, Sergey; Simon, Hans-Uwe; Barlev, Nickolai A (2023). Phytochemicals Target Multiple Metabolic Pathways in Cancer. Antioxidants, 12(11) MDPI 10.3390/antiox12112012
Wortmann, Julian Kleine; Barco, Stefano; Fumagalli, Riccardo M; Voci, Davide; Hügel, Ulrike; Cola, Rahel; Spirk, David; Kucher, Nils; Sebastian, Tim (2023). Coagulation-monitored, dose-adjusted catheter-directed thrombolysis or pharmaco-mechanical thrombus removal in deep vein thrombosis. Vasa - European journal of vascular medicine, 52(6), pp. 416-422. Huber 10.1024/0301-1526/a001097
Barco, Stefano; Virdone, Saverio; Götschi, Andrea; Ageno, Walter; Arcelus, Juan I; Bingisser, Roland; Colucci, Giuseppe; Cools, Frank; Duerschmied, Daniel; Gibbs, Harry; Fumagalli, Riccardo M; Gerber, Bernhard; Haas, Sylvia; Himmelreich, Jelle C L; Hobbs, Richard; Hobohm, Lukas; Jacobson, Barry; Kayani, Gloria; Lopes, Renato D; MacCallum, Peter; ... (2023). Enoxaparin for symptomatic COVID-19 managed in the ambulatory setting: An individual patient level analysis of the OVID and ETHIC trials. Thrombosis research, 230, pp. 27-32. Elsevier 10.1016/j.thromres.2023.08.009
Koster, Kira-Lee; Messerich, Nora-Medea; Volken, Thomas; Cogliatti, Sergio; Lehmann, Thomas; Graf, Lukas; Holbro, Andreas; Benz, Rudolf; Demmer, Izadora; Jochum, Wolfram; Tata, Nageswara Rao; Silzle, Tobias (2023). Prognostic Significance of the Myelodysplastic Syndrome-Specific Comorbidity Index (MDS-CI) in Patients with Myelofibrosis: A Retrospective Study. Cancers, 15(19) MDPI AG 10.3390/cancers15194698
Plattner, Kevin; Sousa Augusto, Gilles; Muerner, Lukas; von Gunten, Stephan; Jörg, Lukas; Engeroff, Paul; Bachmann, Martin F; Vogel, Monique (2023). IgE glycosylation is essential for the function of omalizumab. Allergy, 78(9), pp. 2546-2549. Wiley 10.1111/all.15748
Biccirè, Flavio G; Häner, Jonas; Losdat, Sylvain; Ueki, Yasushi; Shibutani, Hiroki; Otsuka, Tatsuhiko; Kakizaki, Ryota; Hofbauer, Thomas M; van Geuns, Robert-Jan; Stortecky, Stefan; Siontis, Georgios Cm; Bär, Sarah; Lønborg, Jacob; Heg, Dik; Kaiser, Christoph; Spirk, David; Daemen, Joost; Iglesias, Juan; Windecker, Stephan; Engstrøm, Thomas; ... (2023). Concomitant Coronary Atheroma Regression and Stabilization in Response to Lipid-Lowering Therapy. Journal of the American College of Cardiology, 82(18), pp. 1737-1747. Elsevier 10.1016/j.jacc.2023.08.019
Brichkina, Anna; Simon, Hans-Uwe (2023). A novel role for mitochondrial fission in macrophages: trained innate immunity induced by beta-glucan. Cellular & molecular immunology, 20(8), pp. 864-866. Springer Nature 10.1038/s41423-023-01017-w
Kueng, Nicholas; Sidler, Daniel; Banz, Vanessa; Largiadèr, Carlo R; Ng, Charlotte K Y; Amstutz, Ursula (2023). Investigation of Different Library Preparation and Tissue of Origin Deconvolution Methods for Urine and Plasma cfDNA Methylome Analysis. Diagnostics, 13(15) MDPI 10.3390/diagnostics13152505
Bär, Sarah; Kavaliauskaite, Raminta; Otsuka, Tatsuhiko; Ueki, Yasushi; Häner, Jonas D; Siontis, George C M; Stortecky, Stefan; Shibutani, Hiroki; Temperli, Fabrice; Kaiser, Christoph; Iglesias, Juan; Jan van Geuns, Robert; Daemen, Joost; Spirk, David; Engstrøm, Thomas; Lang, Irene; Windecker, Stephan; Koskinas, Konstantinos C; Losdat, Sylvain and Räber, Lorenz (2023). Impact of alirocumab on plaque regression and haemodynamics of non-culprit arteries in patients with acute myocardial infarction: a prespecified substudy of the PACMAN-AMI trial. EuroIntervention, 19(4), e286-e296. Europa Digital & Publishing 10.4244/EIJ-D-23-00201
Gigon, Lea; Fettrelet, Timothée; Yousefi, Shida; Simon, Dagmar; Simon, Hans-Uwe (2023). Eosinophils from A to Z. Allergy, 78(7), pp. 1810-1846. Wiley 10.1111/all.15751
Valenzuela, Pedro L; Ruilope, Luis M; Santos-Lozano, Alejandro; Wilhelm, Matthias; Kränkel, Nicolle; Fiuza-Luces, Carmen; Lucia, Alejandro (2023). Exercise benefits in cardiovascular diseases: from mechanisms to clinical implementation. European Heart Journal, 44(21), pp. 1874-1889. Oxford University Press 10.1093/eurheartj/ehad170
Huwiler, Andrea (2023). Topical Collection: New Insights on Sphingolipids in Health and Disease. International journal of molecular sciences, 24(11) MDPI 10.3390/ijms24119528
Erger, Florian; Aryal, Rajindra P; Reusch, Björn; Matsumoto, Yasuyuki; Meyer, Robert; Zeng, Junwei; Knopp, Cordula; Noel, Maxence; Muerner, Lukas; Wenzel, Andrea; Kohl, Stefan; Tschernoster, Nikolai; Rappl, Gunter; Rouvet, Isabelle; Schröder-Braunstein, Jutta; Seibert, Felix S; Thiele, Holger; Häusler, Martin G; Weber, Lutz T; Büttner-Herold, Maike; ... (2023). Germline C1GALT1C1 mutation causes a multisystem chaperonopathy. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 120(22), e2211087120. National Academy of Sciences 10.1073/pnas.2211087120
Vitale, Ilio; Pietrocola, Federico; Guilbaud, Emma; Aaronson, Stuart A; Abrams, John M; Adam, Dieter; Agostini, Massimiliano; Agostinis, Patrizia; Alnemri, Emad S; Altucci, Lucia; Amelio, Ivano; Andrews, David W; Aqeilan, Rami I; Arama, Eli; Baehrecke, Eric H; Balachandran, Siddharth; Bano, Daniele; Barlev, Nickolai A; Bartek, Jiri; Bazan, Nicolas G; ... (2023). Apoptotic cell death in disease-Current understanding of the NCCD 2023. Cell death and differentiation, 30(5), pp. 1097-1154. Nature Publishing Group 10.1038/s41418-023-01153-w
Démoulins, Thomas; Schulze, Kai; Ebensen, Thomas; Techakriengkrai, Navapon; Nedumpun, Teerawut; Englezou, Pavlos C; Gerber, Markus; Hlushchuk, Ruslan; Toledo, Darien; Djonov, Valentin; von Gunten, Stephan; McCullough, Kenneth C; Liniger, Matthias; Guzmán, Carlos A; Suradhat, Sanipa; Ruggli, Nicolas (2023). Coatsome-replicon vehicles: Self-replicating RNA vaccines against infectious diseases. Nanomedicine : nanotechnology, biology, and medicine, 49(102655), p. 102655. Elsevier 10.1016/j.nano.2023.102655
Zhu, Cui; Potenza, Duilio M; Yang, Yang; Ajalbert, Guillaume; Mertz, Kirsten D; von Gunten, Stephan; Ming, Xiu-Fen; Yang, Zhihong (2023). Role of pulmonary epithelial arginase-II in activation of fibroblasts and lung inflammaging. Aging cell, 22(4), e13790. Wiley 10.1111/acel.13790
Huwiler, Andrea; Beck, Karl-Friedrich; Pfeilschifter, Josef (2023). Cross-Regulation of the Cellular Redox System, Oxygen, and Sphingolipid Signalling. Metabolites, 13(3) MDPI 10.3390/metabo13030426
Peng, Shuang; Gao, Jian; Stojkov, Darko; Yousefi, Shida; Simon, Hans-Uwe (2023). Established and emerging roles for mitochondria in neutrophils. Immunological reviews, 314(1), pp. 413-426. Wiley-Blackwell 10.1111/imr.13158
Voci, Davide; Fedeli, Ugo; Valerio, Luca; Schievano, Elena; Righini, Marc; Kucher, Nils; Spirk, David; Barco, Stefano (2023). Mortality rate related to peripheral arterial disease: A retrospective analysis of epidemiological data (years 2008-2019). Nutrition, metabolism, and cardiovascular diseases : NMCD, 33(3), pp. 516-522. Elsevier 10.1016/j.numecd.2022.11.020
Messerich, Nora-Medea; Uda, Narasimha Rao; Volken, Thomas; Cogliatti, Sergio; Lehmann, Thomas; Holbro, Andreas; Benz, Rudolf; Graf, Lukas; Gupta, Vikas; Jochum, Wolfram; Demmer, Izadora; Tata, Nageswara Rao; Silzle, Tobias (2023). CRP/Albumin Ratio and Glasgow Prognostic Score Provide Prognostic Information in Myelofibrosis Independently of MIPSS70-A Retrospective Study. Cancers, 15(5) MDPI AG 10.3390/cancers15051479
Imeri, Faik; Stepanovska Tanturovska, Bisera; Manaila, Roxana; Pavenstädt, Hermann; Pfeilschifter, Josef; Huwiler, Andrea (2023). Loss of S1P Lyase Expression in Human Podocytes Causes a Reduction in Nephrin Expression That Involves PKCδ Activation. International journal of molecular sciences, 24(4) MDPI 10.3390/ijms24043267
Stepanovska Tanturovska, Bisera; Manaila, Roxana; Fabbro, Doriano; Huwiler, Andrea (2023). Lipids as Targets for Renal Cell Carcinoma Therapy. International journal of molecular sciences, 24(4) MDPI 10.3390/ijms24043272
Simon, Hans-Uwe (2023). Legends of Allergology and Immunology: Alex Straumann. Allergy, 78(2), pp. 596-598. Wiley-Blackwell 10.1111/all.15520
Hosseini, Aref; Stojkov, Darko; Fettrelet, Timothée; Bilyy, Rostyslav; Yousefi, Shida; Simon, Hans-Uwe (2023). Transcriptional Insights of Oxidative Stress and Extracellular Traps in Lung Tissues of Fatal COVID-19 Cases. International journal of molecular sciences, 24(3) MDPI 10.3390/ijms24032646
Almizraq, Ruqayyah J; Frias Boligan, Kayluz; Lewis, Bonnie J B; Cen, Selena; Whetstone, Heather; Spirig, Rolf; Käsermann, Fabian; Campbell, Ian K; von Gunten, Stephan; Branch, Donald R (2023). Modulation of Neutrophil Function by Recombinant Human IgG1 Fc Hexamer in the Endogenous K/BxN Mouse Model of Rheumatoid Arthritis. Pharmacology, 108(2), pp. 176-187. Karger 10.1159/000528780
Stojkov, Darko; Claus, Meike J; Kozlowski, Evelyne; Oberson, Kevin; Schaeren, Olivier P; Benarafa, Charaf; Yousefi, Shida; Simon, Hans-Uwe (2023). NET formation is independent of gasdermin D and pyroptotic cell death. Science signaling, 16(769), eabm0517. American Association for the Advancement of Science 10.1126/scisignal.abm0517
Kaufmann, Thomas; Simon, Hans-Uwe (2023). Pharmacological Induction of Granulocyte Cell Death As Therapeutic Strategy. Annual review of pharmacology and toxicology, 63, pp. 231-247. Annual Reviews Inc. 10.1146/annurev-pharmtox-051921-115130
Saliakoura, Maria; Konstantinidou, Georgia (2023). Lipid Metabolic Alterations in KRAS Mutant Tumors: Unmasking New Vulnerabilities for Cancer Therapy. International journal of molecular sciences, 24(2) MDPI 10.3390/ijms24021793
Beyoğlu, Diren; Schwalm, Stephanie; Semmo, Nasser; Huwiler, Andrea; Idle, Jeffrey R (2023). Hepatitis C Virus Infection Upregulates Plasma Phosphosphingolipids and Endocannabinoids and Downregulates Lysophosphoinositols. International journal of molecular sciences, 24(2) MDPI 10.3390/ijms24021407
Valent, Peter; Klion, Amy D; Roufosse, Florence; Simon, Dagmar; Metzgeroth, Georgia; Leiferman, Kristin M; Schwaab, Juliana; Butterfield, Joseph H; Sperr, Wolfgang R; Sotlar, Karl; Vandenberghe, Peter; Hoermann, Gregor; Haferlach, Torsten; Moriggl, Richard; George, Tracy I; Akin, Cem; Bochner, Bruce S; Gotlib, Jason; Reiter, Andreas; Horny, Hans-Peter; ... (2023). Proposed Refined Diagnostic Criteria and Classification of Eosinophil Disorders and Related Syndromes. Allergy, 78(1), pp. 47-59. Wiley 10.1111/all.15544
Voci, Davide; Götschi, Andrea; Held, Ulrike; Bingisser, Roland; Colucci, Giuseppe; Duerschmied, Daniel; Fumagalli, Riccardo M; Gerber, Bernhard; Hasse, Barbara; Keller, Dagmar I; Konstantinides, Stavros V; Mach, François; Rampini, Silvana K; Righini, Marc; Robert-Ebadi, Helia; Rosemann, Thomas; Roth-Zetzsche, Stéphanie; Sebastian, Tim; Simon, Noemi R; Spirk, David; ... (2023). Enoxaparin for outpatients with COVID-19: 90-day results from the randomised, open-label, parallel-group, multinational, phase III OVID trial. Thrombosis research, 221, pp. 157-163. Elsevier 10.1016/j.thromres.2022.10.021
Idrisova, K. F.; Simon, H.-U.; Gomzikova, M. O. (2023). Role of Patient-Derived Models of Cancer in Translational Oncology. Cancers, 15(1), p. 139. MDPI AG 10.3390/cancers15010139
von Gunten, Stephan; Schneider, Christoph; Imamovic, Lejla; Gorochov, Guy (2023). Antibody diversity in IVIG: Therapeutic opportunities for novel immunotherapeutic drugs. Frontiers in immunology, 14, p. 1166821. Frontiers Research Foundation 10.3389/fimmu.2023.1166821
Daks, Alexandra; Shuvalov, Oleg; Fedorova, Olga; Parfenyev, Sergey; Simon, Hans-Uwe; Barlev, Nickolai A (2023). Methyltransferase Set7/9 as a Multifaceted Regulator of ROS Response. International journal of biological sciences, 19(8), pp. 2304-2318. 10.7150/ijbs.83158
Maurer, M; Magerl, M; Betschel, S; Aberer, W; Ansotegui, I J; Aygören-Pürsün, E; Banerji, A; Bara, N A; Boccon-Gibod, I; Bork, K; Bouillet, L; Boysen, H B; Brodszki, N; Busse, P J; Bygum, A; Caballero, T; Cancian, M; Castaldo, A; Cohn, D M; Csuka, D; ... (2023). [Not Available]. Arerugi = [Allergy], 72(3), pp. 237-272. 10.15036/arerugi.72.237
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Gigon, Lea; Fettrelet, Timothée; Miholic, Marta; McLeish, Kenneth R; Yousefi, Shida; Stojkov, Darko; Simon, Hans-Uwe (2023). Syntaxin-4 and SNAP23 are involved in neutrophil degranulation, but not in the release of mitochondrial DNA during NET formation. Frontiers in immunology, 14(1272699), p. 1272699. Frontiers Research Foundation 10.3389/fimmu.2023.1272699
Hosseini, Aref; Germic, Nina; Markov, Nikita; Stojkov, Darko; Oberson, Kevin; Yousefi, Shida; Simon, Hans-Uwe (2023). The regulatory role of eosinophils in adipose tissue depends on autophagy. Frontiers in immunology, 14, p. 1331151. Frontiers Research Foundation 10.3389/fimmu.2023.1331151
von Achenbach, Caroline; Hevia Hernandez, Giselle; von Gunten, Stephan (2022). The Choice between Intravenous and Subcutaneous Immunoglobulins: Aspects for Consideration. Pharmacology, 107(11-12), pp. 556-563. Karger 10.1159/000527655
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Peng, Shuang; Stojkov, Darko; Gao, Jian; Oberson, Kevin; Latzin, Philipp; Casaulta, Carmen; Yousefi, Shida; Simon, Hans-Uwe (2022). Nascent RHOH acts as a molecular brake on actomyosin-mediated effector functions of inflammatory neutrophils. PLoS biology, 20(9), e3001794. Public Library of Science 10.1371/journal.pbio.3001794
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Abjaude, Walason; Prati, Bruna; Munford, Veridiana; Montenegro, Aline; Lino, Vanesca; Herbster, Suellen; Rabachini, Tatiana; Termini, Lara; Menck, Carlos Frederico Martins; Boccardo, Enrique (2022). ATM Pathway Is Essential for HPV-Positive Human Cervical Cancer-Derived Cell Lines Viability and Proliferation. Pathogens, 11(6), p. 637. MDPI AG 10.3390/pathogens11060637
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Valent, Peter; Degenfeld-Schonburg, Lina; Sadovnik, Irina; Horny, Hans-Peter; Arock, Michel; Simon, Hans-Uwe; Reiter, Andreas; Bochner, Bruce S (2021). Eosinophils and eosinophil-associated disorders: immunological, clinical, and molecular complexity. Seminars in immunopathology, 43(3), pp. 423-438. Springer 10.1007/s00281-021-00863-y
Germic, Nina; Hosseini, Aref; Stojkov, Darko; Oberson, Kevin; Claus, Meike; Benarafa, Charaf; Calzavarini, Sara; Angelillo-Scherrer, Anne; Arnold, Isabelle C; Müller, Anne; Riether, Carsten; Yousefi, Shida; Simon, Hans-Uwe (2021). ATG5 promotes eosinopoiesis, but inhibits eosinophil effector functions. Blood, 137(21), pp. 2958-2969. American Society of Hematology 10.1182/blood.2020010208
Germic, Nina; Hosseini, Aref; Yousefi, Shida; Karaulov, Alexander; Simon, Hans-Uwe (2021). Regulation of eosinophil functions by autophagy. Seminars in immunopathology, 43(3), pp. 347-362. Springer 10.1007/s00281-021-00860-1
Spirk, David; Sebastian, Tim; Barco, Stefano; Banyai, Martin; Beer, Jürg H; Mazzolai, Lucia; Baldi, Thomas; Aujesky, Drahomir; Hayoz, Daniel; Engelberger, Rolf P; Kaeslin, Thomas; Korte, Wolfgang; Escher, Robert; Husmann, Marc; Blondon, Marc; Kucher, Nils (2021). Clinical Outcomes of Incidental Venous Thromboembolism in Cancer and Noncancer Patients: The SWIss Venous ThromboEmbolism Registry (SWIVTER). Thrombosis and haemostasis, 121(5), pp. 641-649. Thieme 10.1055/s-0040-1720977
Rohner, Maria Helena; Thormann, Kathrin; Cazzaniga, Simone; Yousefi, Shida; Simon, Hans-Uwe; Schlapbach, Christoph; Simon, Dagmar (2021). Dupilumab reduces inflammation and restores the skin barrier in patients with atopic dermatitis. Allergy, 76(4), pp. 1268-1270. Wiley-Blackwell 10.1111/all.14664
Engeroff, Paul; Plattner, Kevin; Storni, Federico; Storni, Federico; Thoms, Franziska; Frias Boligan, Kayluz; Mürner, Lukas; Eggel, Alexander; von Gunten, Stephan; Bachmann, Martin F.; Vogel, Monique (2021). Glycan-specific IgG anti-IgE autoantibodies are protective against allergic anaphylaxis in a murine model. Journal of allergy and clinical immunology, 147(4), pp. 1430-1441. Elsevier 10.1016/j.jaci.2020.11.031
Imeri, Faik; Stepanovska Tanturovska, Bisera; Schwalm, Stephanie; Saha, Sarbari; Zeng-Brouwers, Jinyang; Pavenstädt, Herrmann; Pfeilschifter, Josef; Schaefer, Liliana; Huwiler, Andrea (2021). Loss of sphingosine kinase 2 enhances Wilm's tumor suppressor gene 1 and nephrin expression in podocytes and protects from streptozotocin-induced podocytopathy and albuminuria in mice. Matrix biology, 98, pp. 32-48. Elsevier 10.1016/j.matbio.2021.05.003
Naim, Samara; Fernández-Marrero, Yuniel; De Brot, Simone; Bachmann, Daniel; Kaufmann, Thomas (2021). Loss of BOK Has a Minor Impact on Acetaminophen Overdose-Induced Liver Damage in Mice. International journal of molecular sciences, 22(6) MDPI 10.3390/ijms22063281
Imeri, Faik; Stepanovska Tanturovska, Bisera; Zivkovic, Aleksandra; Enzmann, Gaby; Schwalm, Stephanie; Pfeilschifter, Josef; Homann, Thomas; Kleuser, Burkhard; Engelhardt, Britta; Stark, Holger; Huwiler, Andrea (2021). Novel compounds with dual S1P receptor agonist and histamine H3 receptor antagonist activities act protective in a mouse model of multiple sclerosis. Neuropharmacology, 186, p. 108464. Elsevier 10.1016/j.neuropharm.2021.108464
Scholz, Irene; Liakoni, Evangelia; Hammann, Felix; Grafinger, Katharina Elisabeth; Duthaler, Urs; Nagler, Michael; Krähenbühl, Stephan; Haschke, Manuel (2021). Effects of Hypericum perforatum (St John's wort) on the pharmacokinetics and pharmacodynamics of rivaroxaban in humans. British journal of clinical pharmacology, 87(3), pp. 1466-1474. Wiley-Blackwell 10.1111/bcp.14553
Schwalm, Stephanie; Beyer, Sandra; Hafizi, Redona; Trautmann, Sandra; Geisslinger, Gerd; Adams, David R; Pyne, Susan; Pyne, Nigel; Schaefer, Liliana; Huwiler, Andrea; Pfeilschifter, Josef (2021). Validation of highly selective sphingosine kinase 2 inhibitors SLM6031434 and HWG-35D as effective anti-fibrotic treatment options in a mouse model of tubulointerstitial fibrosis. Cellular signalling, 79(109881), p. 109881. Elsevier 10.1016/j.cellsig.2020.109881
Leroux, Cédric; Konstantinidou, Georgia (2021). Targeted Therapies for Pancreatic Cancer: Overview of Current Treatments and New Opportunities for Personalized Oncology. Cancers, 13(4) MDPI AG 10.3390/cancers13040799
Psarra, Anastasia; Theodoropoulou, Maria A; Erhardt, Martin; Mertiri, Marina; Mantzourani, Christiana; Vasilakaki, Sofia; Magrioti, Victoria; Huwiler, Andrea; Kokotos, George (2021). α-Ketoheterocycles Able to Inhibit the Generation of Prostaglandin E2 (PGE2) in Rat Mesangial Cells. Biomolecules, 11(2) MDPI 10.3390/biom11020275
Germic, Nina; Fettrelet, Timothée; Stojkov, Darko; Hosseini, Aref; Horn, Michael P.; Karaulov, Alexander; Simon, Dagmar; Yousefi, Shida; Simon, Hans-Uwe (2021). The Release Kinetics of Eosinophil Peroxidase and Mitochondrial DNA Is Different in Association with Eosinophil Extracellular Trap Formation. Cells, 10(2) MDPI 10.3390/cells10020306
Biedermann, Luc; Holbreich, Mark; Atkins, Dan; Chehade, Mirna; Dellon, Evan S; Furuta, Glenn T; Hirano, Ikuo; Gonsalves, Nirmala; Greuter, Thomas; Katzka, David A; De Rooij, Willemijn; Safroneeva, Ekaterina; Schoepfer, Alain; Schreiner, Philipp; Simon, Dagmar; Simon, Hans Uwe; Warners, Marijn; Bredenoord, Albert-Jan; Straumann, Alex (2021). Food-induced Immediate Response of the Esophagus - a newly identified Syndrome in Patients with Eosinophilic Esophagitis. Allergy, 76(1), pp. 339-347. Wiley-Blackwell 10.1111/all.14495
Gigon, Lea; Yousefi, Shida; Karaulov, Alexander; Simon, Hans-Uwe (2021). Mechanisms of toxicity mediated by neutrophil and eosinophil granule proteins. Allergology international, 70(1), pp. 30-38. Elsevier 10.1016/j.alit.2020.11.003
Klionsky, Daniel J; Abdel-Aziz, Amal Kamal; Abdelfatah, Sara; Abdellatif, Mahmoud; Abdoli, Asghar; Abel, Steffen; Abeliovich, Hagai; Abildgaard, Marie H; Abudu, Yakubu Princely; Acevedo-Arozena, Abraham; Adamopoulos, Iannis E; Adeli, Khosrow; Adolph, Timon E; Adornetto, Annagrazia; Aflaki, Elma; Agam, Galila; Agarwal, Anupam; Aggarwal, Bharat B; Agnello, Maria; Agostinis, Patrizia; ... (2021). Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy, 17(1), pp. 1-382. Taylor & Francis 10.1080/15548627.2020.1797280
Wang, Junhua; von Gunten, Stephan; Beldi, Guido; Grandgirard, Denis; Leib, Stephen L.; Gottstein, Bruno (2021). Digest the Sugar, Kill the Parasite: A New Experimental Concept in Treating Alveolar Echinococcosis. Pharmacology, 106(1-2), pp. 3-8. Karger 10.1159/000509355
Wang, Xiaoliang; Avsec, Damjan; Obreza, Aleš; Yousefi, Shida; Mlinarič-Raščan, Irena; Simon, Hans-Uwe (2021). A Putative Serine Protease is Required to Initiate the RIPK3-MLKL-Mediated Necroptotic Death Pathway in Neutrophils. Frontiers in Pharmacology, 11, p. 614928. Frontiers 10.3389/fphar.2020.614928
Cummings, Richard D; von Gunten, Stephan (2021). Targeting the Laminated Layer of Echinococcus multilocularis as a Potential Therapeutic Strategy. Pharmacology, 106(1-2), pp. 1-2. Karger 10.1159/000512769
Dalakas, Marinos C.; Späth, Peter J. (2021). The importance of FcRn in neuro-immunotherapies: From IgG catabolism, FCGRT gene polymorphisms, IVIg dosing and efficiency to specific FcRn inhibitors. Therapeutic advances in neurological disorders, 14, p. 1756286421997381. Sage 10.1177/1756286421997381
Bruno, Andreina; Di Sano, Caterina; Simon, Hans-Uwe; Chanez, Pascal; Patti, Angelo Maria; Di Vincenzo, Serena; Dino, Paola; D'Esposito, Vittoria; Formisano, Pietro; Beguinot, Francesco; Pace, Elisabetta (2021). Leptin and TGF-β1 Downregulate PREP1 Expression in Human Adipose-Derived Mesenchymal Stem Cells and Mature Adipocytes. Frontiers in cell and developmental biology, 9, p. 700481. Frontiers 10.3389/fcell.2021.700481
Frangez, Ziva; Gérard, Deborah; He, Zhaoyue; Gavriil, Marios; Fernández-Marrero, Yuniel; Jafari, S. Morteza Seyed; Hunger, Robert E.; Lucarelli, Philippe; Yousefi, Shida; Sauter, Thomas; Sinkkonen, Lasse; Simon, Hans-Uwe (2021). ATG5 and ATG7 Expression Levels Are Reduced in Cutaneous Melanoma and Regulated by NRF1. Frontiers in oncology, 11, p. 721624. Frontiers Research Foundation 10.3389/fonc.2021.721624
Holvoet, Sébastien; Nutten, Sophie; Dupuis, Lénaïck; Donnicola, Dominique; Bourdeau, Tristan; Hughes-Formella, Betsy; Simon, Dagmar; Simon, Hans-Uwe; Carvalho, Ryan S.; Spergel, Jonathan M.; Koletzko, Sibylle; Blanchard, Carine (2021). Partially Hydrolysed Whey-Based Infant Formula Improves Skin Barrier Function. Nutrients, 13(9), p. 3113. MDPI 10.3390/nu13093113
Burgener, Sabrina Sofia; Brügger, Melanie; Leborgne, Nathan Georges François; Sollberger, Sophia; Basilico, Paola; Kaufmann, Thomas; Bird, Phillip Ian; Benarafa, Charaf (2021). Granule Leakage Induces Cell-Intrinsic, Granzyme B-Mediated Apoptosis in Mast Cells. Frontiers in cell and developmental biology, 9, p. 630166. Frontiers 10.3389/fcell.2021.630166
Nagler, Michael; Asmis, Lars M.; Gerber, Bernhard; Ruosch, Sabine; Spirk, David; Surbek, Daniel; Studt, Jan-Dirk; Tsakiris, Dimitrios A.; Wuillemin, Walter A. (2021). Venöse Thromboembolie in Gynäkologie und Geburtshilfe. Swiss Medical Forum, 21(29-30), pp. 503-508. EMH Swiss Medical Publishers 10.4414/smf.2021.08773
Hugonnet, Marjolaine; Singh, Pushpita; Haas, Quentin; von Gunten, Stephan (2021). The Distinct Roles of Sialyltransferases in Cancer Biology and Onco-Immunology. Frontiers in immunology, 12, p. 799861. Frontiers Research Foundation 10.3389/fimmu.2021.799861
von Gunten, Stephan; Simon, Hans-Uwe (2020). Linking glucocorticoid-induced osteoporosis to osteoimmunology. Cell death & disease, 11(12), p. 1026. Nature Publishing Group 10.1038/s41419-020-03250-x
Piacentini, Mauro; Shi, Yufang; Simon, Hans-Uwe (2020). 10 years of Cell Death & Disease. Cell death & disease, 11(12), p. 1064. Springer Nature 10.1038/s41419-020-03287-y
Arnold, Isabelle C; Artola-Boran, Mariela; Gurtner, Alessandra; Bertram, Katrin; Bauer, Michael; Frangez, Ziva; Becher, Burkhard; Kopf, Manfred; Yousefi, Shida; Simon, Hans-Uwe; Tzankov, Alexandar; Müller, Anne (2020). The GM-CSF-IRF5 signaling axis in eosinophils promotes antitumor immunity through activation of type 1 T cell responses. Journal of experimental medicine, 217(12) Rockefeller University Press 10.1084/jem.20190706
Yu, Yi; Ladeiras, Diogo; Xiong, Yuyan; Frias Boligan, Kayluz; Liang, Xiujie; von Gunten, Stephan; Hunger, Robert E.; Ming, Xiu-Fen; Yang, Zhihong (2020). Arginase-II promotes melanoma migration and adhesion through enhancing hydrogen peroxide production and STAT3 signaling. Journal of cellular physiology, 235(12), pp. 9997-10011. Wiley 10.1002/jcp.29814
Sebastian, Tim; Gnanapiragasam, Suvetha; Spirk, David; Engelberger, Rolf Peter; Moeri, Laura; Lodigiani, Corrado; Kreuzpointner, Robert; Barco, Stefano; Kucher, Nils (2020). Self-Expandable Nitinol Stents for the Treatment of Nonmalignant Deep Venous Obstruction. Circulation. Cardiovascular interventions, 13(12), pp. 366-374. American Heart Association 10.1161/CIRCINTERVENTIONS.120.009673
Wehrli, Marc; Schneider, Christoph; Cortinas-Elizondo, Fabiola; Verschoor, Daniëlle; Frias Boligan, Kayluz; Adams, Olivia Joan; Hlushchuk, Ruslan; Engelmann, Christine; Daudel, Fritz; Villiger, Peter M.; Seibold, Frank; Yawalkar, Nikhil; Vonarburg, Cédric; Miescher, Sylvia; Lötscher, Marius; Kaufmann, Thomas; Münz, Christian; Mueller, Christoph; Djonov, Valentin; Simon, Hans-Uwe; ... (2020). IgA Triggers Cell Death of Neutrophils When Primed by Inflammatory Mediators. Journal of immunology, 205(10), pp. 2640-2648. American Association of Immunologists 10.4049/jimmunol.1900883
Brandl, Fabian; Busslinger, Sarah; Zangemeister-Wittke, Uwe; Plückthun, Andreas (2020). Optimizing the anti-tumor efficacy of protein-drug conjugates by engineering the molecular size and half-life. Journal of controlled release, 327, pp. 186-197. Elsevier 10.1016/j.jconrel.2020.08.004
Wahn, V; Aberer, W; Aygören-Pürsün, E; Bork, K; Eberl, W; Faßhauer, M; Krüger, R; Magerl, M; Martinez-Saguer, I; Späth, P.; Staubach-Renz, P; Weber-Chrysochoou, C (2020). Hereditary angioedema in children and adolescents - A consensus update on therapeutic strategies for German-speaking countries. Pediatric allergy and immunology, 31(8), pp. 974-989. Wiley-Blackwell 10.1111/pai.13309
Saliakoura, Maria; Rossi Sebastiano, Matteo; Pozzato, Chiara; Heidel, Florian H.; Schnöder, Tina M.; Savic Prince, Spasenija; Bubendorf, Lukas; Pinton, Paolo; Schmid, Ralph A.; Baumgartner, Johanna; Freigang, Stefan; Berezowska, Sabina A.; Rimessi, Alessandro; Konstantinidou, Georgia (2020). PLCγ1 suppression promotes the adaptation of KRAS-mutant lung adenocarcinomas to hypoxia. Nature cell biology, 22(11), pp. 1382-1395. Springer Nature 10.1038/s41556-020-00592-8
Dalakas, Marinos C; Alexopoulos, Harry; Späth, Peter J (2020). Complement in neurological disorders and emerging complement-targeted therapeutics. Nature reviews. Neurology, 16(11), pp. 601-617. Nature Publishing Group 10.1038/s41582-020-0400-0
Dennhardt, Sophie; Finke, Karl R; Huwiler, Andrea; Coldewey, Sina M (2020). Corrigendum to "Sphingosine-1-phosphate promotes barrier-stabilizing effects in human microvascular endothelial cells via AMPK-dependent mechanisms" [Biochim. Biophys. Acta Mol. Basis Dis. 2019 Apr 1;1865(4):774-781]. Biochimica et biophysica acta - molecular basis of disease, 1866(10), p. 165892. Elsevier 10.1016/j.bbadis.2020.165892
Schreiner, Philipp; Meissgeier, Silas; Safroneeva, Ekaterina; Greuter, Thomas; Rogler, Gerhard; Schoepfer, Alain; Simon, Dagmar; Simon, Hans-Uwe; Biedermann, Luc; Straumann, Alex (2020). Disease Progression and Outcomes of Pregnancies in Women With Eosinophilic Esophagitis. Clinical gastroenterology and hepatology, 18(11), pp. 2456-2462. Elsevier 10.1016/j.cgh.2019.11.057
Wandrer, Franziska; Frangež, Živa; Liebig, Stephanie; John, Katharina; Vondran, Florian; Wedemeyer, Heiner; Veltmann, Christian; Pfeffer, Tobias J; Shibolet, Oren; Schulze-Osthoff, Klaus; Simon, Hans-Uwe; Bantel, Heike (2020). Autophagy alleviates amiodarone-induced hepatotoxicity. Archives of toxicology, 94(10), pp. 3527-3539. Springer-Verlag 10.1007/s00204-020-02837-9
Rossi Sebastiano, Matteo; Pozzato, Chiara; Saliakoura, Maria; Zhang, Yang; Peng, Ren-Wang; Galiè, Mirco; Oberson, Kevin; Simon, Hans-Uwe; Karamitopoulou, Evanthia; Konstantinidou, Georgia (2020). ACSL3-PAI-1 signaling axis mediates tumor-stroma cross-talk promoting pancreatic cancer progression. Science Advances, 6(44), pp. 1-15. American Association for the Advancement of Science 10.1126/sciadv.abb9200
Frangez, Z; Jafari, S M Seyed; Hunger, R E; Simon, H-U (2020). Loss of Concurrent Regulation of the Expression of BIF-1, BAX, and Beclin-1 in Primary and Metastatic Melanoma. Biochemistry (Moscow), 85(10), pp. 1227-1234. Pleiades 10.1134/S0006297920100107
Luetscher, Ralph N D; McKitrick, Tanya R; Gao, Chao; Mehta, Akul Y; McQuillan, Alyssa M; Kardish, Robert; Frias Boligan, Kayluz; Song, Xuezheng; Lu, Lenette; Heimburg-Molinaro, Jamie; von Gunten, Stephan; Alter, Galit; Cummings, Richard D (2020). Unique repertoire of anti-carbohydrate antibodies in individual human serum. Scientific reports, 10(1), p. 15436. Springer Nature 10.1038/s41598-020-71967-y
Wang, Xiaoliang; Gessier, Francois; Perozzo, Remo; Stojkov, Darko; Hosseini, Aref; Amirshahrokhi, Keyvan; Kuchen, Stefan; Yousefi, Shida; Lötscher, Pius; Simon, Hans-Uwe (2020). RIPK3-MLKL-Mediated Neutrophil Death Requires Concurrent Activation of Fibroblast Activation Protein-α. Journal of immunology, 205(6), pp. 1653-1663. American Association of Immunologists 10.4049/jimmunol.2000113
von Gunten, Stephan (2020). Inflamm-Aging: Arginase-II as Stage Setter in Age-Related Adipose Tissue Inflammation. Pharmacology, 105(9-10), pp. 489-490. Karger 10.1159/000510515
Stepanovska, Bisera; Zivkovic, Aleksandra; Enzmann, Gaby; Tietz, Silvia; Homann, Thomas; Kleuser, Burkhard; Engelhardt, Britta; Stark, Holger; Huwiler, Andrea (2020). Morpholino Analogues of Fingolimod as Novel and Selective S1P1 Ligands with In Vivo Efficacy in a Mouse Model of Experimental Antigen-Induced Encephalomyelitis. International journal of molecular sciences, 21(18), pp. 1-17. MDPI 10.3390/ijms21186463
Sebastian, Tim; Barco, Stefano; Engelberger, Rolf P; Spirk, David; Schindewolf, Marc; Baumann, Frederic; Baumgartner, Iris; Kucher, Nils (2020). Duplex Ultrasound Investigation for the Detection of Obstructed Iliocaval Venous Stents. European journal of vascular and endovascular surgery EJVES, 60(3), pp. 443-450. Elsevier 10.1016/j.ejvs.2020.05.011
Naim, Samara; Kaufmann, Thomas (2020). The Multifaceted Roles of the BCLL-2 Family Member BOK. Frontiers in cell and developmental biology, 8 Frontiers 10.3389/fcell.2020.574338
Simon, Hans-Uwe; Karaulov, Alexander V; Bachmann, Martin F. (2020). Strategies to Prevent SARS-CoV-2-Mediated Eosinophilic Disease in Association with COVID-19 Vaccination and Infection. International archives of allergy and immunology, 181(8), pp. 624-628. Karger 10.1159/000509368
Liu, He; He, Zhaoyue; Germič, Nina; Ademi, Hyrijie; Frangež, Živa; Felser, Andrea; Peng, Shuang; Riether, Carsten; Djonov, Valentin; Nuoffer, Jean-Marc; Bovet, Cédric; Mlinarič-Raščan, Irena; Zlobec, Inti; Fiedler, Georg; Perren, Aurel; Simon, Hans-Uwe (2020). ATG12 deficiency leads to tumor cell oncosis owing to diminished mitochondrial biogenesis and reduced cellular bioenergetics. Cell death and differentiation, 27(6), pp. 1965-1980. Springer Nature 10.1038/s41418-019-0476-5
Frangež, Živa; Fernández-Marrero, Yuniel; Stojkov, Darko; Seyed Jafari, S. Morteza; Hunger, Robert E.; Djonov, Valentin; Riether, Carsten; Simon, Hans-Uwe (2020). BIF-1 inhibits both mitochondrial and glycolytic ATP production: its downregulation promotes melanoma growth. Oncogene, 39(26), pp. 4944-4955. Springer Nature 10.1038/s41388-020-1339-8
Karlen, Hélène; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (2020). IL-15 Expression Pattern in Atopic Dermatitis. International archives of allergy and immunology, 181(6), pp. 417-421. Karger 10.1159/000508515
Yousefi, Shida; Simon, Dagmar; Stojkov, Darko; Karsonova, Antonina; Karaulov, Alexander; Simon, Hans-Uwe (2020). In vivo evidence for extracellular DNA trap formation. Cell death & disease, 11(4), p. 300. Nature Publishing Group 10.1038/s41419-020-2497-x
Graeter, Stefanie; Simon, Hans-Uwe; von Gunten, Stephan (2020). Granulocyte death mediated by specific antibodies in intravenous immunoglobulin (IVIG). Pharmacological research, 154, p. 104168. Elsevier 10.1016/j.phrs.2019.02.007
Stepanovska, Bisera; Huwiler, Andrea (2020). Targeting the S1P receptor signaling pathways as a promising approach for treatment of autoimmune and inflammatory diseases. Pharmacological research, 154, p. 104170. Elsevier 10.1016/j.phrs.2019.02.009
Saliakoura, Maria; Reynoso-Moreno, Inés; Pozzato, Chiara; Rossi Sebastiano, Matteo; Galié, Mirco; Gertsch, Jürg; Konstantinidou, Georgia (2020). The ACSL3-LPIAT1 signaling drives prostaglandin synthesis in non-small cell lung cancer. Oncogene, 39(14), pp. 2948-2960. Springer Nature 10.1038/s41388-020-1196-5
Maurer, Marcus; Eyerich, Kilian; Eyerich, Stefanie; Ferrer, Marta; Gutermuth, Jan; Hartmann, Karin; Jakob, Thilo; Kapp, Alexander; Kolkhir, Pavel; Larenas-Linnemann, Désirée; Park, Hae-Sim; Pejler, Gunnar; Sánchez-Borges, Mario; Schäkel, Knut; Simon, Dagmar; Simon, Hans-Uwe; Weller, Karsten; Zuberbier, Torsten; Metz, Martin (2020). Urticaria: Collegium Internationale Allergologicum (CIA) Update 2020. International archives of allergy and immunology, 181(5), pp. 321-333. Karger 10.1159/000507218
Ramadori, Giorgio; Ioris, Rafael M; Villanyi, Zoltan; Firnkes, Raquel; Panasenko, Olesya O; Allen, George; Konstantinidou, Georgia; Aras, Ebru; Brenachot, Xavier; Biscotti, Tommasina; Charollais, Anne; Luchetti, Michele; Bezrukov, Fedor; Santinelli, Alfredo; Samad, Muntaha; Baldi, Pierre; Collart, Martine A; Coppari, Roberto (2020). FKBP10 Regulates Protein Translation to Sustain Lung Cancer Growth. Cell reports, 30(11), pp. 3851-863. Cell Press 10.1016/j.celrep.2020.02.082
Müller, Ines; Strozyk, Elwira; Schindler, Sebastian; Beissert, Stefan; Oo, Htoo Zarni; Sauter, Thomas; Lucarelli, Philippe; Raeth, Sebastian; Hausser, Angelika; Al Nakouzi, Nader; Fazli, Ladan; Gleave, Martin E; Liu, He; Simon, Hans-Uwe; Walczak, Henning; Green, Douglas R; Bartek, Jiri; Daugaard, Mads; Kulms, Dagmar (2020). Cancer Cells Employ Nuclear Caspase-8 to Overcome the p53-Dependent G2/M Checkpoint through Cleavage of USP28. Molecular cell, 77(5), 970-984.e7. Cell Press 10.1016/j.molcel.2019.12.023
Sterlin, Delphine; Fadlallah, Jehane; Adams, Olivia; Fieschi, Claire; Parizot, Christophe; Dorgham, Karim; Rajkumar, Asok; Autaa, Gaëlle; El-Kafsi, Hela; Charuel, Jean-Luc; Juste, Catherine; Jönsson, Friederike; Candela, Thomas; Wardemann, Hedda; Aubry, Alexandra; Capito, Carmen; Brisson, Hélène; Tresallet, Christophe; Cummings, Richard D; Larsen, Martin; ... (2020). Human IgA binds a diverse array of commensal bacteria. Journal of experimental medicine, 217(3) Rockefeller University Press 10.1084/jem.20181635
Sterlin, Delphine; Fadlallah, Jehane; Adams, Olivia; Fieschi, Claire; Parizot, Christophe; Dorgham, Karim; Rajkumar, Asok; Autaa, Gaëlle; El-Kafsi, Hela; Charuel, Jean-Luc; Juste, Catherine; Jönsson, Friederike; Candela, Thomas; Wardemann, Hedda; Aubry, Alexandra; Capito, Carmen; Brisson, Hélène; Tresallet, Christophe; Cummings, Richard D; Larsen, Martin; ... (2020). Correction: Human IgA bind a diverse array of commensal bacteria. Journal of experimental medicine, 217(3) Rockefeller University Press 10.1084/jem.2018163501152020c
Simon, Dagmar; Yousefi, Shida; Cazzaniga, Simone; Bürgler, Christina; Radonjic, Susanne; Houriet, Carine; Heidemeyer, Kristine; Klötgen, Hans-Willhelm; Kozlowski, Evelyne; Borradori, Luca; Simon, Hans-Uwe (2020). Mepolizumab failed to affect bullous pemphigoid: a randomized, placebo-controlled, double-blind phase 2 pilot study. Allergy, 75(3), pp. 669-672. Wiley 10.1111/all.13950
Grafinger, Katharina Elisabeth; Liechti, Matthias E; Liakoni, Evangelia (2020). Clinical value of analytical testing in patients presenting with New Psychoactive Substances intoxication. British journal of clinical pharmacology, 86(3), pp. 429-436. Wiley-Blackwell 10.1111/bcp.14115
Boligan, Kayluz F.; Oechtering, Johanna; Keller, Christian W; Peschke, Benjamin; Rieben, Robert; Bovin, Nicolai; Kappos, Ludwig; Cummings, Richard D; Kuhle, Jens; von Gunten, Stephan; Lünemann, Jan D (2020). Xenogeneic Neu5Gc and self-glycan Neu5Ac epitopes are potential immune targets in MS. Neurology: Neuroimmunology and Neuroinflammation, 7(2) Wolters Kluwer Health 10.1212/NXI.0000000000000676
Spinetti, Thibaud; Meisel, Christian; von Gunten, Stephan; Schefold, Joerg C. (2020). Immune biomarker-based enrichment in sepsis trials. Critical care, 24(1), p. 58. BioMed Central 10.1186/s13054-020-2774-1
Schwalm, Stephanie; Erhardt, Martin; Römer, Isolde; Pfeilschifter, Josef; Zangemeister-Wittke, Uwe; Huwiler, Andrea (2020). Ceramide Kinase Is Upregulated in Metastatic Breast Cancer Cells and Contributes to Migration and Invasion by Activation of PI 3-Kinase and Akt. International journal of molecular sciences, 21(4) MDPI 10.3390/ijms21041396
Stepanovska, Bisera; Lange, Antonia I; Schwalm, Stephanie; Pfeilschifter, Josef; Coldewey, Sina M; Huwiler, Andrea (2020). Downregulation of S1P Lyase Improves Barrier Function in Human Cerebral Microvascular Endothelial Cells Following an Inflammatory Challenge. International journal of molecular sciences, 21(4) MDPI 10.3390/ijms21041240
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He, Zhaoyue; Liu, He; Moch, Holger; Simon, Hans-Uwe (2020). Machine learning with autophagy-related proteins for discriminating renal cell carcinoma subtypes. Scientific reports, 10(1), p. 720. Springer Nature 10.1038/s41598-020-57670-y
Rohner, Lionel; Reinhart, Ramona; Iype, Joseena; Bachmann, Sofia; Kaufmann, Thomas; Fux, Michaela (2020). Impact of BH3-mimetics on Human and Mouse Blood Leukocytes: A Comparative Study. Scientific reports, 10(1), p. 222. Springer Nature 10.1038/s41598-019-57000-x
Cazzaniga, Simone; Wiedmer, Christina; Frangež, Živa; Shafighi, Maziar; Beltraminelli, Helmut; Weber, Benedikt; Simon, Dagmar; Naldi, Luigi; Simon, Hans-Uwe; Hunger, Robert E.; Seyed Jafari, S. Morteza (2020). Association of Vascular Endothelial Growth Factor Subtypes with Melanoma Patients' Characteristics and Survival: A Semantic Connectivity Map Analysis. Acta dermato-venereologica, 100(1), adv00019. Forum for Nordic Dermato-Venereology 10.2340/00015555-3374
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Markov, Nikita; Simon, Hans-Uwe (2020). IL-37: A new player in the chronic rhinosinusitis arena. The Journal of allergy and clinical immunology, 145(1), pp. 105-107. Elsevier 10.1016/j.jaci.2019.10.018
Surmiak, Marcin; Gielicz, Anna; Stojkov, Darko; Szatanek, Rafał; Wawrzycka-Adamczyk, Katarzyna; Yousefi, Shida; Simon, Hans-Uwe; Sanak, Marek (2020). LTB4 and 5-oxo-ETE from extracellular vesicles stimulate neutrophils in granulomatosis with polyangiitis. Journal of lipid research, 61(1), pp. 1-9. American Society for Biochemistry and Molecular Biology ASBMB 10.1194/jlr.M092072
Simon, Hans-Uwe; Yousefi, Shida; Germic, Nina; Arnold, Isabelle C.; Haczku, Angela; Karaulov, Alexander V.; Simon, Dagmar; Rosenberg, Helene F. (2020). The Cellular Functions of Eosinophils: Collegium Internationale Allergologicum (CIA) Update 2020. International archives of allergy and immunology, 181(1), pp. 11-23. Karger 10.1159/000504847
von Gunten, Stephan (2020). The Future of Pharmacology: Towards More Personalized Pharmacotherapy and Reverse Translational Research. Pharmacology, 105(1-2), pp. 1-2. Karger 10.1159/000505216
Spirk, David; Noll, Sarah; Burnier, Michel; Rimoldi, Stefano; Noll, Georg; Sudano, Isabella (2020). First Line CombinAtion Therapy in the Treatment of Stage II and III Hypertension (FLASH). Frontiers in cardiovascular medicine, 7(46), p. 46. Frontiers 10.3389/fcvm.2020.00046
Konstantinidou, Georgia; Rimessi, Alessandro (2020). Editorial: Oncogenic RAS-Dependent Reprogramming of Cellular Plasticity. Frontiers in oncology, 10(588), p. 588. Frontiers Research Foundation 10.3389/fonc.2020.00588
von Gunten, Stephan (2020). Secondary-Type Carbohydrate Modification as a Driver of Epithelial-Mesenchymal Transition and Features of Cancer Stem Cells. Pharmacology, 105(5-6), pp. 244-245. Karger 10.1159/000507003
Graeter, Stefanie; Schneider, Christoph; Verschoor, Daniëlle; von Däniken, Sandro; Seibold, Frank; Yawalkar, Nikhil; Villiger, Peter; Dimitrov, Jordan D; Smith, David F; Cummings, Richard D; Simon, Hans-Uwe; Vassilev, Tchavdar; von Gunten, Stephan (2020). Enhanced Pro-apoptotic Effects of Fe(II)-Modified IVIG on Human Neutrophils. Frontiers in immunology, 11(973), p. 973. Frontiers Research Foundation 10.3389/fimmu.2020.00973
Liakoni, Evangelia; Berger, Flavia; Klukowska-Rötzler, Jolanta; Kupferschmidt, Hugo; Haschke, Manuel; Exadaktylos, Aristomenis (2019). Characteristics of emergency department presentations requiring consultation of the national Poisons Information Centre. Swiss medical weekly, 149, w20164. EMH Media 10.4414/smw.2019.20164
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Gjuroski, Ilche; Girousi, Eleftheria; Meyer, Christoph; Hertig, Damian; Stojkov, Darko; Fux, Michaela; Schnidrig, Nicolas; Bucher, Jan; Pfister, Sara; Sauser, Luca; Simon, Hans-Uwe; Vermathen, Peter; Furrer, Julien; Vermathen, Martina (2019). Evaluation of polyvinylpyrrolidone and block copolymer micelle encapsulation of serine chlorin e6 and chlorin e4 on their reactivity towards albumin and transferrin and their cell uptake. Journal of controlled release, 316, pp. 150-167. Elsevier 10.1016/j.jconrel.2019.10.010
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Srivastava, Rahul; Cao, Zhipeng; Nedeva, Christina; Naim, Samara; Bachmann, Daniel; Rabachini, Tatiana; Gangoda, Lahiru; Shahi, Sanjay; Glab, Jason; Menassa, Joseph; Osellame, Laura; Nelson, Tao; Fernández Marrero, Yuniel; Brown, Fiona; Wei, Andrew; Ke, Francine; O'Reilly, Lorraine; Doerflinger, Marcel; Allison, Cody; Kueh, Andrew; ... (2019). BCL-2 family protein BOK is a positive regulator of uridine metabolism in mammals. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 116(31), pp. 15469-15474. National Academy of Sciences NAS 10.1073/pnas.1904523116
Rossi Sebastiano, Matteo; Konstantinidou, Georgia (2019). Targeting Long Chain Acyl-CoA Synthetases for Cancer Therapy. International journal of molecular sciences, 20(15) MDPI 10.3390/ijms20153624
Dorvignit, Denise; Frias Boligan, Kayluz; Relova-Hernández, Ernesto; Clavell, Marilyn; López, Armando; Labrada, Mayrel; Simon, Hans-Uwe; López-Requena, Alejandro; Mesa, Circe; von Gunten, Stephan (2019). Antitumor effects of the GM3(Neu5Gc) ganglioside-specific humanized antibody 14F7hT against Cmah-transfected cancer cells. Scientific Reports, 9(1), p. 9921. Nature Publishing Group 10.1038/s41598-019-46148-1
Karra, Laila; Gangwar, Roopesh Singh; Puzzovio, Pier Giorgio; Fyhrquist, Nanna; Minai-Fleminger, Yael; Landolina, Nadine; Simon, Hans-Uwe; Alenius, Harri; Leibovici, Vera; Simon, Dagmar; Levi-Schaffer, Francesca (2019). CD300a expression is modulated in atopic dermatitis and could influence the inflammatory response. Allergy, 74(7), pp. 1377-1380. Wiley 10.1111/all.13724
Bruno, Andreina; Di Sano, Caterina; Lorusso, Francesco; Dino, Paola; Russo, Domenica; Ballacchino, Antonella; Gallina, Salvatore; Modica, Domenico Michele; Chiappara, Giuseppina; Simon, Hans-Uwe; Pace, Elisabetta (2019). Notch-1 decreased expression contributes to leptin receptor downregulation in nasal epithelium from allergic turbinates. Biochimica et biophysica acta - molecular basis of disease, 1865(6), pp. 1642-1650. Elsevier 10.1016/j.bbadis.2019.03.016
Liu, He; He, Zhaoyue; April, Simon Leonhard; Trefny, Marcel Philipp; Rougier, Jean-Sébastien; Salemi, Souzan; Olariu, Radu; Widmer, Hans Rudolf; Simon, Hans-Uwe (2019). Biochemical re-programming of human dermal stem cells to neurons by increasing mitochondrial membrane potential. Cell death and differentiation, 26(6), pp. 1048-1061. Nature Publishing Group 10.1038/s41418-018-0182-8
Simon, Dagmar; Simon, Hans-Uwe (2019). Therapeutic strategies for eosinophilic dermatoses. Current opinion in pharmacology, 46, pp. 29-33. Elsevier 10.1016/j.coph.2019.01.002
Leviatan Ben-Arye, Shani; Schneider, Christoph; Yu, Hai; Bashir, Salam; Chen, Xi; von Gunten, Stephan; Padler-Karavani, Vered (2019). Differential Recognition of Diet-Derived Neu5Gc-Neoantigens on Glycan Microarrays by Carbohydrate-Specific Pooled Human IgG and IgA Antibodies. Bioconjugate chemistry, 30(5), pp. 1565-1574. American Chemical Society 10.1021/acs.bioconjchem.9b00273
Sokollik, Christiane; Simon, Hans-Uwe (2019). [Eosinophilic granulocytes-Physiology and pathophysiology]. Zeitschrift für Rheumatologie, 78(4), pp. 306-312. Springer-Medizin-Verlag 10.1007/s00393-018-0574-7
Haas, Quentin; Frias Boligan, Kayluz; Jandus, Camilla; Schneider, Christoph; Simillion, Cedric; Stanczak, Michal A; Haubitz, Monika; Jafari, Morteza; Zippelius, Alfred; Baerlocher, Gabriela M.; Läubli, Heinz; Hunger, Robert E.; Romero, Pedro; Simon, Hans-Uwe; von Gunten, Stephan (2019). Siglec-9 Regulates an Effector Memory CD8 T-cell Subset That Congregates in the Melanoma Tumor Microenvironment. Cancer immunology research, 7(5), pp. 707-718. American Association for Cancer Research 10.1158/2326-6066.CIR-18-0505
Dennhardt, Sophie; Finke, Karl R; Huwiler, Andrea; Coldewey, Sina M (2019). Sphingosine-1-phosphate promotes barrier-stabilizing effects in human microvascular endothelial cells via AMPK-dependent mechanisms. Biochimica et biophysica acta - molecular basis of disease, 1865(4), pp. 774-781. Elsevier 10.1016/j.bbadis.2018.12.022
Yadav, Sandeep Kumar; Stojkov, Darko; Feigelson, Sara W; Roncato, Francesco; Simon, Hans-Uwe; Yousefi, Shida; Alon, Ronen (2019). Chemokine-triggered microtubule polymerization promotes neutrophil chemotaxis and invasion but not transendothelial migration. Journal of leukocyte biology, 105(4), pp. 755-766. Society for Leukocyte Biology 10.1002/JLB.3A1118-437RR
Boeltz, Sebastian; Amini, Poorya; Anders, Hans-Joachim; Andrade, Felipe; Bilyy, Rostyslav; Chatfield, Simon; Cichon, Iwona; Clancy, Danielle M; Desai, Jyaysi; Dumych, Tetiana; Dwivedi, Nishant; Gordon, Rachael Ann; Hahn, Jonas; Hidalgo, Andrés; Hoffmann, Markus H; Kaplan, Mariana J; Knight, Jason S; Kolaczkowska, Elzbieta; Kubes, Paul; Leppkes, Moritz; ... (2019). To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps. Cell death and differentiation, 26(3), pp. 395-408. Nature Publishing Group 10.1038/s41418-018-0261-x
Germic, Nina; Frangez, Ziva; Yousefi, Shida; Simon, Hans-Uwe (2019). Regulation of the innate immune system by autophagy: monocytes, macrophages, dendritic cells and antigen presentation. Cell death and differentiation, 26(4), pp. 715-727. Nature Publishing Group 10.1038/s41418-019-0297-6
Germic, Nina; Frangez, Ziva; Yousefi, Shida; Simon, Hans-Uwe (2019). Regulation of the innate immune system by autophagy: neutrophils, eosinophils, mast cells, NK cells. Cell death and differentiation, 26(4), pp. 703-714. Nature Publishing Group 10.1038/s41418-019-0295-8
Simon, Dagmar; Wollenberg, Andreas; Renz, Harald; Simon, Hans-Uwe (2019). Atopic Dermatitis: Collegium Internationale Allergologicum (CIA) Update 2019. International archives of allergy and immunology, 178(3), pp. 207-218. Karger 10.1159/000497383
Mortezavi, Ashkan; Salemi, Souzan; Kranzbühler, Benedikt; Gross, Oliver; Sulser, Tullio; Simon, Hans-Uwe; Eberli, Daniel (2019). Inhibition of autophagy significantly increases the antitumor effect of Abiraterone in prostate cancer. World journal of urology, 37(2), pp. 351-358. Springer-Verlag 10.1007/s00345-018-2385-5
Yousefi, Shida; Stojkov, Darko; Germic, Nina; Simon, Dagmar; Wang, Xiaoliang; Benarafa, Charaf; Simon, Hans-Uwe (2019). Untangling "NETosis" from NETs. European journal of immunology, 49(2), pp. 221-227. Wiley-VCH 10.1002/eji.201747053
Schnetzler, Gabriel; Bremgartner, Markus F; Grossmann Straessle, Regina; Spirk, David; Tay, Fabian; Troxler Saxer, Rahel; Traber, Martin (2019). Evolution to a Competency-Based Training Curriculum for Pharmaceutical Medicine Physicians in Switzerland. Frontiers in Pharmacology, 10(164), p. 164. Frontiers 10.3389/fphar.2019.00164
Leuppi, Jörg D; Schmid-Grendelmeier, Peter; Rothe, Thomas; von Garnier, Christophe; Simon, Hans-Uwe; Schuoler, Claudio; Pendl, Gunther; Solèr, Markus (2019). [Benralizumab: Targeting the IL-5 Receptor in Severe Eosinophilic Asthma]. Praxis, 108(7), pp. 1-8. Hogrefe 10.1024/1661-8157/a003250
Leuppi, Jörg D; Schmid-Grendelmeier, Peter; Rothe, Thomas; von Garnier, Christophe; Simon, Hans-Uwe; Schuoler, Claudio; Pendl, Gunther; Solèr, Markus (2019). [Benralizumab: Targeting the IL-5 Receptor in Severe Eosinophilic Asthma]. Praxis, 108(7), pp. 469-476. Hogrefe 10.1024/1661-8157/a003222
Merten, Hannes; Schaefer, Jonas V; Brandl, Fabian; Zangemeister-Wittke, Uwe; Plückthun, Andreas (2019). Facile Site-Specific Multiconjugation Strategies in Recombinant Proteins Produced in Bacteria. Methods in molecular biology, 2033, pp. 253-273. Springer 10.1007/978-1-4939-9654-4_17
Verschoor, Daniëlle; von Gunten, Stephan (2019). Allergy and Atopic Diseases: An Update on Experimental Evidence. International archives of allergy and immunology, 180(4), pp. 235-243. Karger 10.1159/000504439
Simon, Dagmar; Simon, Hans-Uwe (2019). The role of pharmacists (In Press). In: Brockow, Brockow; Mortz, Charlotte (eds.) Global atlas of skin allergy (pp. 276-278). European academy of allergy and clinical immunology
Keller, Sarah A; Klukowska-Rötzler, Jolanta; Schenk-Jaeger, Katharina M; Kupferschmidt, Hugo; Exadaktylos, Aristomenis; Lehmann, Beat; Liakoni, Evangelia (2018). Mushroom Poisoning-A 17 Year Retrospective Study at a Level I University Emergency Department in Switzerland. International journal of environmental research and public health, 15(12) MDPI 10.3390/ijerph15122855
Sebastian, Tim; Hakki, Lawrence O; Spirk, David; Baumann, Frederic A; Périard, Daniel; Banyai, Martin; Spescha, Rebecca S; Kucher, Nils; Engelberger, Rolf P (2018). Rivaroxaban or vitamin-K antagonists following early endovascular thrombus removal and stent placement for acute iliofemoral deep vein thrombosis. Thrombosis research, 172, pp. 86-93. Elsevier 10.1016/j.thromres.2018.10.027
Fernández Marrero, Yuniel; Bachmann, Daniel; Lauber, Emanuel; Kaufmann, Thomas (2018). Negative Regulation of BOK Expression by Recruitment of TRIM28 to Regulatory Elements in Its 3' Untranslated Region. iScience, 9, pp. 461-474. Elsevier 10.1016/j.isci.2018.11.005
Basaco, Tais; Pektor, Stefanie; Bermudez, Josue M.; Meneses, Niurka; Heller, Manfred; Galván, José A.; Frias Boligan, Kayluz; Schürch, Stefan; von Gunten, Stephan; Türler, Andreas; Miederer, Matthias (2018). Evaluation of Radiolabeled Girentuximab In Vitro and In Vivo. Pharmaceuticals, 11(4) MDPI 10.3390/ph11040132
Sandbaumhüter, Friederike Andrea; Haschke, Manuel Martin; Vogt, Bruno; Bohlender, Jürgen (2018). Medication adherence during laboratory workup for primary aldosteronism: pilot study. Patient preference and adherence, 12, pp. 2449-2455. Dove Medical Press 10.2147/PPA.S179488
Stanczak, Michal A; Siddiqui, Shoib S; Trefny, Marcel P; Thommen, Daniela S; Frias Boligan, Kayluz; von Gunten, Stephan; Tzankov, Alexandar; Tietze, Lothar; Lardinois, Didier; Heinzelmann-Schwarz, Viola; von Bergwelt-Baildon, Michael S; Zhang, Wu; Lenz, Heinz-Josef; Han, Younghan; Amos, Christopher I; Syedbasha, Mohammedyaseen; Egli, Adrian; Stenner, Frank; Speiser, Daniel E; Varki, Ajit; ... (2018). Self-associated molecular patterns mediate cancer immune evasion by engaging Siglecs on T cells. Journal of clinical investigation, 128(11), pp. 4912-4923. American Society for Clinical Investigation 10.1172/JCI120612
Eberli, Daniel; Horst, Maya; Mortezavi, Ashkan; Andersson, Karl-Erik; Gobet, Rita; Sulser, Tullio; Simon, Hans-Uwe; Salemi, Souzan (2018). Increased autophagy contributes to impaired smooth muscle function in neurogenic lower urinary tract dysfunction. Neurourology and urodynamics, 37(8), pp. 2414-2424. Wiley-Liss 10.1002/nau.23705
Rohner, Lionel; Reinhart, Ramona; Hagmann, Björn; Odermatt, Andrea; Babirye, Annet; Kaufmann, Thomas; Fux, Michaela (2018). FcɛRI cross-linking and IL-3 protect human basophils from intrinsic apoptotic stress. The Journal of allergy and clinical immunology, 142(5), 1647-1650.e3. Elsevier 10.1016/j.jaci.2018.06.040
Evangelopoulos, Maria Eleftheria; Miclea, Andrei; Schrewe, Lisa; Briner, Myriam; Salmen, Anke; Engelhardt, Britta; Huwiler, Andrea; Chan, Andrew; Hoepner, Robert (2018). Frequency and clinical characteristics of Multiple Sclerosis rebounds after withdrawal of Fingolimod. CNS neuroscience & therapeutics, 24(10), pp. 984-986. Wiley 10.1111/cns.12992
Miserez, A R; Martin, F J; Spirk, David (2018). DIAgnosis and Management Of familial hypercholesterolemia in a Nationwide Design (DIAMOND-FH): Prevalence in Switzerland, clinical characteristics and the diagnostic value of clinical scores. Atherosclerosis, 277, pp. 282-288. Elsevier 10.1016/j.atherosclerosis.2018.08.009
Adams, Olivia Joan; Stanczak, Michal A; von Gunten, Stephan; Läubli, Heinz (2018). Targeting sialic acid-Siglec interactions to reverse immune suppression in cancer. Glycobiology, 28(9), pp. 640-647. Oxford University Press 10.1093/glycob/cwx108
Miethe, Sarah; Guarino, Maria; Alhamdan, Fahd; Simon, Hans-Uwe; Renz, Harald; Dufour, Jean-François; Potaczek, Daniel P; Garn, Holger (2018). Effects of obesity on asthma: immunometabolic links. Polish archives of internal medicine, 128(7-8), pp. 469-477. Medycyna Praktyczna, Kraków, Poland 10.20452/pamw.4304
Arnold, Isabelle C; Artola-Borán, Mariela; Tallón de Lara, Paulino; Kyburz, Andreas; Taube, Christian; Ottemann, Karen; van den Broek, Maries; Yousefi, Shida; Simon, Hans-Uwe; Müller, Anne (2018). Eosinophils suppress Th1 responses and restrict bacterially induced gastrointestinal inflammation. Journal of experimental medicine, 215(8), pp. 2055-2072. Rockefeller University Press 10.1084/jem.20172049
Huwiler, Andrea; Pfeilschifter, Josef (2018). Sphingolipid signaling in renal fibrosis. Matrix biology, 68-69, pp. 230-247. Elsevier 10.1016/j.matbio.2018.01.006
Amini, Poorya; Stojkov, Darko; Felser, Andrea; Jackson, Christopher B; Courage, Carolina; Schaller, André; Gelman, Laurent; Soriano, Maria Eugenia; Nuoffer, Jean-Marc; Scorrano, Luca; Benarafa, Charaf; Yousefi, Shida; Simon, Hans-Uwe (2018). Neutrophil extracellular trap formation requires OPA1-dependent glycolytic ATP production. Nature communications, 9(1), p. 2958. Nature Publishing Group 10.1038/s41467-018-05387-y
Sauser, Julien; Nutten, Sophie; de Groot, Nanda; Pecquet, Sophie; Simon, Dagmar; Simon, Hans-Uwe; Spergel, Jonathan M; Koletzko, Sibylle; Blanchard, Carine (2018). Partially Hydrolyzed Whey Infant Formula: Literature Review on Effects on Growth and the Risk of Developing Atopic Dermatitis in Infants from the General Population. International archives of allergy and immunology, 177(2), pp. 123-134. Karger 10.1159/000489861
Yousefi, Shida; Sharma, Satish K; Stojkov, Darko; Germic, Nina; Aeschlimann, Salome; Ge, Moyar Q; Flayer, Cameron H; Larson, Erik D; Redai, Imre G; Zhang, Suhong; Koziol-White, Cynthia J; Karikó, Katalin; Simon, Hans-Uwe; Haczku, Angela (2018). Oxidative damage of SP-D abolishes control of eosinophil extracellular DNA trap formation. Journal of leukocyte biology, 104(1), pp. 205-214. Society for Leukocyte Biology 10.1002/JLB.3AB1117-455R
Khoury, Paneez; Akuthota, Praveen; Ackerman, Steven J; Arron, Joseph R; Bochner, Bruce S; Collins, Margaret H; Kahn, Jean-Emmanuel; Fulkerson, Patricia C; Gleich, Gerald J; Gopal-Srivastava, Rashmi; Jacobsen, Elizabeth A; Leiferman, Kristen M; Francesca, Levi-Schaffer; Mathur, Sameer K; Minnicozzi, Michael; Prussin, Calman; Rothenberg, Marc E; Roufosse, Florence; Sable, Kathleen; Simon, Dagmar; ... (2018). Revisiting the NIH Taskforce on the Research needs of Eosinophil-Associated Diseases (RE-TREAD). Journal of leukocyte biology, 104(1), pp. 69-83. Society for Leukocyte Biology 10.1002/JLB.5MR0118-028R
Reinhart, Ramona; Kaufmann, Thomas (2018). IL-4 enhances survival of in vitro-differentiated mouse basophils through transcription-independent signaling downstream of PI3K. Cell death & disease, 9(7), p. 713. Nature Publishing Group 10.1038/s41419-018-0754-z
Blanchard, Olivier; Stepanovska, Bisera; Starck, Manuel Thierry; Erhardt, Martin; Römer, Isolde; Meyer Zu Heringdorf, Dagmar; Pfeilschifter, Josef; Zangemeister-Wittke, Uwe; Huwiler, Andrea (2018). Downregulation of the S1P Transporter Spinster Homology Protein 2 (Spns2) Exerts an Anti-Fibrotic and Anti-Inflammatory Effect in Human Renal Proximal Tubular Epithelial Cells. International journal of molecular sciences, 19(5) MDPI 10.3390/ijms19051498
Huwiler, Andrea; Zangemeister-Wittke, Uwe (2018). The sphingosine 1-phosphate receptor modulator fingolimod as a therapeutic agent: recent findings and new perspectives. Pharmacology & therapeutics, 185, pp. 34-49. Elsevier 10.1016/j.pharmthera.2017.11.001
de Graauw, E; Sitaru, C; Horn, Michael; Borradori, Luca; Yousefi, Shida; Simon, Dagmar; Simon, Hans-Uwe (2018). Monocytes enhance neutrophil-induced blister formation in an ex vivo model of bullous pemphigoid. Allergy, 73(5), pp. 1119-1130. Wiley-Blackwell 10.1111/all.13376
Sebastian, Tim; Dopheide, Jörn F.; Engelberger, Rolf P.; Spirk, David; Kucher, Nils (2018). Outcomes of endovascular reconstruction of the inferior vena cava with self-expanding nitinol stents. Journal of vascular surgery. Venous and lymphatic disorders, 6(3), pp. 312-320. Elsevier 10.1016/j.jvsv.2017.11.012
Späth, Peter Julius (2018). Essentials of the Production of Safe and Efficacious State-of-the-Art Polyclonal IgG Concentrates. In: Imbach, P. (ed.) Antibody Therapy (pp. 151-173). Springer 10.1007/978-3-319-68038-5_12
Wahn, Volker; Späth, Peter Julius (2018). Historical Aspects of Polyclonal IgG Preparations. In: Imbach, P. (ed.) Antibody Therapy (pp. 121-132). Springer 10.1007/978-3-319-68038-5_10
Prince Eladnani, Raja; Bologna, Luca; Manetti, Mirko; Melchiorre, Daniela; Rosa, Irene; Dewarrat, Natacha; Suardi, Silvia; Amini, Poorya; Fernández, José A; Burnier, Laurent; Quarroz, Claudia; Reina Caro, Maria Desiré; Matsumura, Yasuhiro; Kremer Hovinga, Johanna Anna; Griffin, John H; Simon, Hans-Uwe; Ibba-Manneschi, Lidia; Saller, François; Calzavarini, Sara and Angelillo, Anne (2018). Targeting anticoagulant protein S to improve hemostasis in hemophilia. Blood, 131(12), pp. 1360-1371. American Society of Hematology 10.1182/blood-2017-09-800326
Gevaert, Elien; Yousefi, Shida; Bachert, Claus; Simon, Hans-Uwe (2018). Reply. The Journal of allergy and clinical immunology, 141(3), pp. 1164-1165. Elsevier 10.1016/j.jaci.2017.05.048
Rabachini de Almeida, Tatiana; Fernández Marrero, Yuniel; Montani, Matteo; Loforese, Giulio; Sladky, Valentina; He, Zhaoyue; Bachmann, Daniel; Wicki, Simone; Villunger, Andreas; Keogh-Stroka, Deborah M.; Kaufmann, Thomas (2018). BOK promotes chemical-induced hepatocarcinogenesis in mice. Cell death and differentiation, 25(4), pp. 706-718. Nature Publishing Group 10.1038/s41418-017-0008-0
Schoepfer, Alain M; Simko, Audrey; Bussmann, Christian; Safroneeva, Ekaterina; Zwahlen, Marcel; Greuter, Thomas; Biedermann, Luc; Vavricka, Stephan; Godat, Sébastien; Reinhard, Antoine; Saner, Catherine; Maye, Hugo; Sempoux, Christine; Brunel, Christophe; Blanchard, Carine; Simon, Dagmar; Simon, Hans-Uwe; Straumann, Alex (2018). Eosinophilic Esophagitis: Relationship of Subepithelial Eosinophilic Inflammation With Epithelial Histology, Endoscopy, Blood Eosinophils, and Symptoms. American journal of gastroenterology, 113(3), pp. 348-357. Nature 10.1038/ajg.2017.493
Simon, Hans-Uwe; Bieber, Thomas (2018). Allergy - Committed to Progress in Allergy and Immunology. Allergy, 73(3), p. 527. Wiley-Blackwell 10.1111/all.13412
Galluzzi, Lorenzo; Vitale, Ilio; Aaronson, Stuart A; Abrams, John M; Adam, Dieter; Agostinis, Patrizia; Alnemri, Emad S; Altucci, Lucia; Amelio, Ivano; Andrews, David W; Annicchiarico-Petruzzelli, Margherita; Antonov, Alexey V; Arama, Eli; Baehrecke, Eric H; Barlev, Nickolai A; Bazan, Nicolas G; Bernassola, Francesca; Bertrand, Mathieu J M; Bianchi, Katiuscia; Blagosklonny, Mikhail V; ... (2018). Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. Cell death and differentiation, 25(3), pp. 486-541. Nature Publishing Group 10.1038/s41418-017-0012-4
Haas, Quentin; Simillion, Cedric André Marie; von Gunten, Stephan (2018). A Cartography of Siglecs and Sialyltransferases in Gynecologic Malignancies: Is There a Road Towards a Sweet Future? Frontiers in oncology, 8, p. 68. Frontiers Research Foundation 10.3389/fonc.2018.00068
Späth, Peter Julius (2018). Current IgG Products and Future Perspectives. In: Imbach, P. (ed.) Antibody Therapy (pp. 175-202). Springer 10.1007/978-3-319-68038-5_13
Wicki, Simone; Gurzeler, Ursina; Corazza, Nadia; Genitsch, Vera; Wong, Wendy Wei-Lynn; Kaufmann, Thomas (2018). Loss of BID Delays FASL-Induced Cell Death of Mouse Neutrophils and Aggravates DSS-Induced Weight Loss. International journal of molecular sciences, 19(3) MDPI 10.3390/ijms19030684
Eresch, Jeanette; Stumpf, Martin; Koch, Alexander; Vutukuri, Rajkumar; Ferreirós, Nerea; Schreiber, Yannick; Schröder, Katrin; Devraj, Kavi; Popp, Rüdiger; Huwiler, Andrea; Hattenbach, Lars-Olof; Pfeilschifter, Josef; Pfeilschifter, Waltraud (2018). Sphingosine Kinase 2 Modulates Retinal Neovascularization in the Mouse Model of Oxygen-Induced Retinopathy. Investigative ophthalmology & visual science, 59(2), pp. 653-661. Association for Research in Vision and Ophthalmology 10.1167/iovs.17-22544
Wang, Xiaoliang; Yousefi, Shida; Simon, Hans-Uwe (2018). Necroptosis and neutrophil-associated disorders. Cell death & disease, 9(2), p. 111. Nature Publishing Group 10.1038/s41419-017-0058-8
Vasilakaki, Sofia; Pastukhov, Oleksandr; Mavromoustakos, Thomas; Huwiler, Andrea; Kokotos, George (2018). Small Peptides Able to Suppress Prostaglandin E₂ Generation in Renal Mesangial Cells. Molecules, 23(1) MDPI 10.3390/molecules23010158
Simon, Hans-Uwe (2018). International Archives of Allergy and Immunology: A Commitment to Serving the Community Worldwide. International archives of allergy and immunology, 175(1-2), pp. 3-4. Karger 10.1159/000485942
Simon, Dagmar; Page, Basile; Vogel, Monique; Bussmann, Christian; Blanchard, Carine; Straumann, Alex; Simon, Hans-Uwe (2018). Evidence of an abnormal epithelial barrier in active, untreated and corticosteroid-treated eosinophilic esophagitis. Allergy, 73(1), pp. 239-247. Wiley-Blackwell 10.1111/all.13244
Reinhart, Ramona; Rohner, Lionel; Wicki, Simone; Fux, Michaela; Kaufmann, Thomas (2018). BH3 mimetics efficiently induce apoptosis in mouse basophils and mast cells. Cell death and differentiation, 25(1), pp. 204-216. Nature Publishing Group 10.1038/cdd.2017.154
Blondon, Marc; Spirk, David; Kucher, Nils; Aujesky, Drahomir; Hayoz, Daniel; Beer, Jürg H; Husmann, Marc; Frauchiger, Beat; Korte, Wolfgang; Wuillemin, Walter Alfred; Bounameaux, Henri; Righini, Marc; Nendaz, Mathieu (2018). Comparative Performance of Clinical Risk Assessment Models for Hospital-Acquired Venous Thromboembolism in Medical Patients. Thrombosis and haemostasis, 118(1), pp. 82-89. Schattauer 10.1160/TH17-06-0403
Jin, Jing; Britschgi, Adrian; Schläfli, Anna M.; Humbert, Magali; Shan-Krauer, Deborah; Batliner, Jasmin; Federzoni, Elena A.; Ernst, Marion; Torbett, Bruce E.; Yousefi, Shida; Simon, Hans-Uwe; Tschan, Mario (2018). Low Autophagy (ATG) Gene Expression Is Associated with an Immature AML Blast Cell Phenotype and Can Be Restored during AML Differentiation Therapy. Oxidative medicine and cellular longevity, 2018, p. 1482795. Hindawi 10.1155/2018/1482795
Simon, Dagmar; Radonjic-Hösli, S.; Straumann, A.; Yousefi, Shida; Simon, Hans-Uwe (2018). Epithelial barrier defects and eosinophil extracellular trap formation in active eosinophilic esophagitis. In: 31st Symposium of the Collegium Internationale Allergologicum (pp. 45-47). Pacini Editore S.r.l.
Beyer, Sandra; Schwalm, Stephanie; Pfeilschifter, Josef; Huwiler, Andrea (2018). Renal Mesangial Cells Isolated from Sphingosine Kinase 2 Transgenic Mice Show Reduced Proliferation and are More Sensitive to Stress-Induced Apoptosis. Cellular physiology and biochemistry, 47(6), pp. 2522-2533. Karger 10.1159/000491625
Liu, He; He, Zhaoyue; Bode, Peter; Moch, Holger; Simon, Hans-Uwe (2018). Downregulation of Autophagy-Related Proteins 1, 5, and 16 in Testicular Germ Cell Tumors Parallels Lowered LC3B and Elevated p62 Levels, Suggesting Reduced Basal Autophagy. Frontiers in oncology, 8(366), p. 366. Frontiers Research Foundation 10.3389/fonc.2018.00366
Seyed Jafari, S. Morteza; Wiedmer, Christina; Cazzaniga, Simone; Frangež, Živa; Shafighi, Maziar; Beltraminelli, Helmut; Weber, Benedikt; Simon, Hans-Uwe; Hunger, Robert E. (2018). Correlation of Vascular Endothelial Growth Factor subtypes and their receptors with melanoma progression: A next-generation Tissue Microarray (ngTMA) automated analysis. PLoS ONE, 13(11), e0207019. Public Library of Science 10.1371/journal.pone.0207019
Adams, Olivia Joan; von Gunten, Stephan (2018). Recent Advances in Experimental Allergy. International archives of allergy and immunology, 177(4), pp. 281-289. Karger 10.1159/000494440
Hübner, Simona T; Bertoli, Raffaela; Rätz Bravo, Alexandra E; Schaueblin, Martina; Haschke, M.; Scherer, Kathrin; Ceschi, Alessandro; Leuppi-Taegtmeyer, Anne B (2018). C-Reactive Protein and Procalcitonin in Case Reports of Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome. International archives of allergy and immunology, 176(1), pp. 44-54. Karger 10.1159/000487670
Liakoni, Evangelia; Gartwyl, Fabienne; Ricklin, Meret; Exadaktylos, Aristomenis; Krähenbühl, Stephan (2018). Psychoactive substances and violent offences: A retrospective analysis of presentations to an urban emergency department in Switzerland. PLoS ONE, 13(3), e0195234. Public Library of Science 10.1371/journal.pone.0195234
Spirk, David; Noll, Sarah; Burnier, Michel; Rimoldi, Stefano; Noll, Georg; Sudano, Isabella (2018). Effect of Home Blood Pressure Monitoring on Patient's Awareness and Goal Attainment Under Antihypertensive Therapy: The Factors Influencing Results in Anti-HypertenSive Treatment (FIRST) Study. Kidney & blood pressure research, 43(3), pp. 979-986. Karger 10.1159/000490687
Stojkov, Darko; Amini, Poorya; Oberson, Kevin; Sokollik, Christiane; Duppenthaler, Andrea; Simon, Hans-Uwe; Yousefi, Shida (2017). ROS and glutathionylation balance cytoskeletal dynamics in neutrophil extracellular trap formation. Journal of cell biology, 216(12), pp. 4073-4090. Rockefeller University Press 10.1083/jcb.201611168
Radonjic-Hoesli, Susanne; Wang, Xiaoliang; de Graauw, Elisabeth Louisa Maria; Stoeckle, Christina; Styp-Rekowska, Beata; Hlushchuk, Ruslan; Simon, Dagmar; Späth, Peter Julius; Yousefi, Shida; Simon, Hans-Uwe (2017). Adhesion-induced eosinophil cytolysis requires the receptor-interacting protein kinase 3 (RIPK3)-mixed lineage kinase-like (MLKL) signaling pathway, which is counterregulated by autophagy. The Journal of allergy and clinical immunology, 140(6), pp. 1632-1642. Elsevier 10.1016/j.jaci.2017.01.044
Simon, Dagmar; Borradori, Luca; Simon, Hans-Uwe (2017). Eosinophils as putative therapeutic targets in bullous pemphigoid. Experimental dermatology, 26(12), pp. 1187-1192. Blackwell 10.1111/exd.13416
Wahn, Ulrich; Matricardi, Paolo M; Bieber, Thomas; Bousquet, Jean; Grattan, Clive; Simon, Hans-Uwe; Muraro, Antonella; Agache, Ioana (2017). Food allergy in EAACI journals (2016). Pediatric allergy and immunology, 28(8), pp. 825-830. Wiley-Blackwell 10.1111/pai.12830
Moravcikova, Erika; Krepela, Evzen; Donnenberg, Vera S; Donnenberg, Albert D; Benkova, Kamila; Rabachini de Almeida, Tatiana; Fernández Marrero, Yuniel; Bachmann, Daniel; Kaufmann, Thomas (2017). BOK displays cell death-independent tumor suppressor activity in non-small cell lung carcinoma. International journal of cancer, 141(10), pp. 2050-2061. Wiley-Blackwell 10.1002/ijc.30906
Germic, Nina; Stojkov, Darko; Oberson, Kevin; Yousefi, Shida; Simon, Hans-Uwe (2017). Neither eosinophils nor neutrophils require ATG5-dependent autophagy for extracellular DNA trap formation. Immunology, 152(3), pp. 517-525. Wiley-Blackwell 10.1111/imm.12790
Alatri, Adriano; Mazzolai, Lucia; Kucher, Nils; Aujesky, Drahomir; Beer, Jürg H; Baldi, Thomas; Banyai, Martin; Hayoz, Daniel; Kaeslin, Thomas; Korte, Wolfgang; Escher, Robert; Husmann, Marc; Frauchiger, Beat; Engelberger, Rolf P.; Baumgartner, Iris; Spirk, David (2017). The Modified Ottawa Score and Clinical Events in Hospitalized Patients with Cancer-Associated Thrombosis from the Swiss VTE Registry. Seminars in thrombosis and hemostasis, 43(8), pp. 871-876. Thieme Medical Publishers 10.1055/s-0037-1604086
Schwalm, Stephanie; Beyer, Sandra; Frey, Helena; Haceni, Riad; Grammatikos, Georgios; Thomas, Dominique; Geisslinger, Gerd; Schaefer, Liliana; Huwiler, Andrea; Pfeilschifter, Josef (2017). Sphingosine Kinase-2 Deficiency Ameliorates Kidney Fibrosis by Up-Regulating Smad7 in a Mouse Model of Unilateral Ureteral Obstruction. American journal of pathology, 187(11), pp. 2413-2429. Elsevier 10.1016/j.ajpath.2017.06.017
Sokollik, Christiane; Simon, Hans-Uwe (2017). Physiologie der eosinophilen Granulozyten. Therapeutische Umschau, 74(6), pp. 291-296. Hogrefe 10.1024/0040-5930/a000917
Spirk, David; Stuck, Anna K.; Hager, A; Engelberger, Rolf P.; Aujesky, Drahomir; Kucher, Nils (2017). Electronic alert system for improving appropriate thromboprophylaxis in hospitalized medical patients: a randomized controlled trial. Journal of thrombosis and haemostasis, 15(11), pp. 2138-2146. Wiley-Blackwell 10.1111/jth.13812
Galluzzi, Lorenzo; Baehrecke, Eric H; Ballabio, Andrea; Boya, Patricia; Bravo-San Pedro, José Manuel; Cecconi, Francesco; Choi, Augustine M; Chu, Charleen T; Codogno, Patrice; Colombo, Maria Isabel; Cuervo, Ana Maria; Debnath, Jayanta; Deretic, Vojo; Dikic, Ivan; Eskelinen, Eeva-Liisa; Fimia, Gian Maria; Fulda, Simone; Gewirtz, David A; Green, Douglas R; Hansen, Malene; ... (2017). Molecular definitions of autophagy and related processes. The EMBO Journal, 36(13), pp. 1811-1836. EMBO Press 10.15252/embj.201796697
de Graauw, Elisabeth Louisa Maria; Sitaru, Cassian; Horn, Michael Peter; Borradori, Luca; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (2017). Evidence for a role of eosinophils in blister formation in bullous pemphigoid. Allergy, 72(7), pp. 1105-1113. Wiley-Blackwell 10.1111/all.13131
Muraro, Antonella; Lemanske, Robert F; Castells, Mariana; Torres, Maria J; Khan, David; Simon, Hans-Uwe; Bindslev-Jensen, Carsten; Burks, Wesley; Poulsen, Lars K; Sampson, Hugh A; Worm, Margitta; Nadeau, Kari C (2017). Precision Medicine in Allergic Disease - Food Allergy, Drug Allergy, and Anaphylaxis-PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology. Allergy, 72(7), pp. 1006-1021. Wiley-Blackwell 10.1111/all.13132
Engelberger, Rolf P.; Stuck, Anna; Spirk, David; Willenberg, Torsten; Haine, Axel; Périard, Daniel; Baumgartner, Iris; Kucher, Nils (2017). Ultrasound-assisted versus conventional catheter-directed thrombolysis for acute ilio-femoral deep vein thrombosis: one-year follow-up data of a randomized-controlled trial. Journal of thrombosis and haemostasis, 15(7), pp. 1351-1360. Wiley-Blackwell 10.1111/jth.13709
Vicari, Alain P; Schoepfer, Alain M; Meresse, Bertrand; Goffin, Laurence; Léger, Olivier; Josserand, Soheila; Guégan, Nicolas; Yousefi, Shida; Straumann, Alex; Cerf-Bensussan, Nadine; Simon, Hans-Uwe; Chvatchko, Yolande (2017). Discovery and characterization of a novel humanized anti-IL-15 antibody and its relevance for the treatment of refractory celiac disease and eosinophilic esophagitis. mAbs, 9(6), pp. 927-944. Taylor & Francis 10.1080/19420862.2017.1332553
Späth, Peter Julius; Schneider, Christoph; von Gunten, Stephan (2017). Clinical Use and Therapeutic Potential of IVIG/SCIG, Plasma-Derived IgA or IgM, and Other Alternative Immunoglobulin Preparations. Archivum immunologiae et therapiae experimentalis, 65(3), pp. 215-231. Springer 10.1007/s00005-016-0422-x
Gevaert, Elien; Zhang, Nan; Krysko, Olga; Lan, Feng; Holtappels, Gabriële; De Ruyck, Natalie; Nauwynck, Hans; Yousefi, Shida; Simon, Hans-Uwe; Bachert, Claus (2017). Extracellular eosinophilic traps in association with Staphylococcus aureus at the site of epithelial barrier defects in severe airway inflammation. The Journal of allergy and clinical immunology, 139(6), 1849-1860.e6. Elsevier 10.1016/j.jaci.2017.01.019
Frias Boligan, Kayluz; von Gunten, Stephan (2017). Innate lymphoid cells in asthma: cannabinoids on the balance. Allergy, 72(6), pp. 839-841. Wiley-Blackwell 10.1111/all.13145
Pilch, Kjara S; Späth, Peter Julius; Yuki, Nobuhiro; Wakerley, Benjamin R (2017). Therapeutic complement inhibition: a promising approach for treatment of neuroimmunological diseases. Expert review of neurotherapeutics, 17(6), pp. 579-591. Expert Reviews 10.1080/14737175.2017.1282821
Schneider, Christoph; Wicki, Simone; Graeter, Stefanie; Maneva Timcheva, Tankica; Keller, Christian W; Quast, Isaak; Leontyev, Danila; Djoumerska-Alexieva, Iglika K; Käsermann, Fabian; Jakob, Stephan; Dimitrova, Petya A; Branch, Donald R; Cummings, Richard D; Lünemann, Jan D; Kaufmann, Thomas; Simon, Hans-Uwe; von Gunten, Stephan (2017). IVIG regulates the survival of human but not mouse neutrophils. Scientific Reports, 7(1), p. 1296. Nature Publishing Group 10.1038/s41598-017-01404-0
Weber, B; Schlapbach, Christoph; Stuck, M; Simon, Hans-Uwe; Borradori, Luca; Beltraminelli, Helmut; Simon, Dagmar (2017). Distinct interferon-gamma and interleukin-9 expression in cutaneous and oral lichen planus. Journal of the European Academy of Dermatology and Venereology, 31(5), pp. 880-886. Wiley 10.1111/jdv.13989
Petrova-Slater, Iveta; Denegri, Andrea; Pasotti, Elena; Rossi, Maria Grazia; Spirk, David; Riesen, Walter F; Moccetti, Tiziano; Moccetti, Marco (2017). [Inhibitors of PCSK9]. Revue médicale suisse, 13(558), pp. 821-825. Médecine & Hygiène
Haimovici, Aladin; Humbert, Magali; Federzoni, Elena A; Shan-Krauer, Deborah; Brunner, Thomas; Frese, Steffen; Kaufmann, Thomas; Torbett, Bruce E; Tschan, Mario (2017). PU.1 supports TRAIL-induced cell death by inhibiting NF-κB-mediated cell survival and inducing DR5 expression. Cell death and differentiation, 24(5), pp. 866-877. Nature Publishing Group 10.1038/cdd.2017.40
Hsieh, Louise Tzung-Harn; Nastase, Madalina-Viviana; Roedig, Heiko; Zeng-Brouwers, Jinyang; Poluzzi, Chiara; Schwalm, Stephanie; Fork, Christian; Tredup, Claudia; Brandes, Ralf P; Wygrecka, Malgorzata; Huwiler, Andrea; Pfeilschifter, Josef; Schaefer, Liliana (2017). Biglycan- and Sphingosine Kinase-1 Signaling Crosstalk Regulates the Synthesis of Macrophage Chemoattractants. International journal of molecular sciences, 18(3) MDPI 10.3390/ijms18030595
Mortezavi, Ashkan; Salemi, Souzan; Rupp, Niels J; Rüschoff, Jan Hendrik; Hermanns, Thomas; Poyet, Cedric; Randazzo, Marco; Simon, Hans-Uwe; Moch, Holger; Sulser, Tullio; Wild, Peter; Eberli, Daniel (2017). Negative LC3b immunoreactivity in cancer cells is an independent prognostic predictor of prostate cancer specific death. OncoTarget, 8(19), pp. 31765-31774. Impact Journals LLC 10.18632/oncotarget.15986
Sharma, Sachin; Kaufmann, Thomas; Biswas, Subhrajit (2017). Impact of inhibitor of apoptosis proteins on immune modulation and inflammation. Immunology and cell biology, 95(3), pp. 236-243. Nature Publishing Group 10.1038/icb.2016.101
McCracken, A N; McMonigle, R J; Tessier, J; Fransson, R; Perryman, M S; Chen, B; Keebaugh, A; Selwan, E; Barr, S A; Kim, S M; Roy, S G; Liu, G; Fallegger, D; Sernissi, L; Brandt, C; Moitessier, N; Snider, A J; Clare, S; Müschen, M; Huwiler, Andrea; ... (2017). Phosphorylation of a constrained azacyclic FTY720 analog enhances anti-leukemic activity without inducing S1P receptor activation. Leukemia, 31(3), pp. 669-677. Nature Publishing Group 10.1038/leu.2016.244
Fernandez-Marrero, Yuniel; Bleicken, Stephanie; Das, Kushal Kumar; Bachmann, Daniel; Kaufmann, Thomas; Garcia-Saez, Ana J (2017). The membrane activity of BOK involves formation of large, stable toroidal pores and is promoted by cBID. FEBS journal, 284(5), pp. 711-724. Wiley-Blackwell 10.1111/febs.14008
Simon, Hans-Uwe; Friis, Robert; Tait, Stephen W G; Ryan, Kevin M (2017). Retrograde signaling from autophagy modulates stress responses. Science signaling, 10(468) American Association for the Advancement of Science 10.1126/scisignal.aag2791
Stuck, Anna K.; Spirk, David; Schaudt, Jil; Kucher, Nils (2017). Risk assessment models for venous thromboembolism in acutely ill medical patients. A systematic review. Thrombosis and haemostasis, 117(4), pp. 801-808. Schattauer 10.1160/TH16-08-0631
Benarafa, Charaf; Simon, Hans-Uwe (2017). Role of granule proteases in the life and death of neutrophils. Biochemical and biophysical research communications, 482(3), pp. 473-481. Academic Press 10.1016/j.bbrc.2016.11.086
Hagmann, B R; Odermatt, A; Kaufmann, Thomas; Dahinden, C A; Fux, Michaela (2017). Balance between IL-3 and type Iinterferons and their interrelationship with FasL dictates lifespan and effector functions of human basophils. Clinical and experimental allergy, 47(1), pp. 71-84. Wiley 10.1111/cea.12850
Lejeune, Alice; Martin, Luise; Santibanez, Sabine; Thee, Stephanie; Gratopp, Alexander; Späth, Peter Julius; Mankertz, Annette; Kallinich, Tilmann; von Bernuth, Horst (2017). Postexposure prophylaxis with intravenous immunoglobulin G prevents infants from getting measles. Acta paediatrica, 106(1), pp. 174-177. Wiley 10.1111/apa.13634
Blanchard, C.; Simon, Dagmar; Schoepfer, A.; Straumann, A.; Simon, Hans-Uwe (2017). Eosinophilic esophagitis: unclear roles of IgE and eosinophils. Journal of internal medicine, 281(5), pp. 448-457. Blackwell Scientific Publications 10.1111/joim.12568
Simon, Hans-Uwe; Friis, Robert; Colombo, María I. (2017). Autophagy. In: eLS Citable reviews in the life sciences (pp. 1-10). Wiley 10.1002/9780470015902.a0021581.pub2
Ioris, Rafael M.; Galié, Mirco; Ramadori, Giorgio; Anderson, Jason G.; Charollais, Anne; Konstantinidou, Georgia; Brenachot, Xavier; Aras, Ebru; Goga, Algera; Ceglia, Nicholas; Sebastián, Carlos; Martinvalet, Denis; Mostoslavsky, Raul; Baldi, Pierre; Coppari, Roberto (2017). SIRT6 Suppresses Cancer Stem-like Capacity in Tumors with PI3K Activation Independently of Its Deacetylase Activity. Cell reports, 18(8), pp. 1858-1868. Cell Press 10.1016/j.celrep.2017.01.065
Kouskoura, Thaleia; Katsaros, Christos; von Gunten, Stephan (2017). The Potential Use of Pharmacological Agents to Modulate Orthodontic Tooth Movement (OTM). Frontiers in physiology, 8(67), p. 67. Frontiers Research Foundation 10.3389/fphys.2017.00067
Graumann, Rebecca; Di Capua, Gabriella A; Oyarzún, Juan E; Vásquez, Marcos A; Liao, Christine; Brañes, Jorge A; Roa, Iván; Casanello, Paola; Corvalán, Alejandro H; Owen, Gareth I; Delgado, Iris; Zangemeister-Wittke, Uwe; Ziegler, Annemarie (2017). Expression of teneurins is associated with tumor differentiation and patient survival in ovarian cancer. PLoS ONE, 12(5), e0177244. Public Library of Science 10.1371/journal.pone.0177244
Schneider, Christoph; Illi, Marlies; Lötscher, Marius; Wehrli, Marc; von Gunten, Stephan (2017). Isolation of Antibodies from Human Plasma, Saliva, Breast Milk, and Gastrointestinal Fluid. Methods in molecular biology, 1643, pp. 23-31. Springer 10.1007/978-1-4939-7180-0_3
Bousquet, Jean; Grattan, Clive; Bieber, Thomas; Matricardi, Paolo; Simon, Hans-Uwe; Wahn, Ulrich; Muraro, Antonella; Hellings, Peter W; Agache, Ioana (2017). Prediction and prevention of allergy and asthma in EAACI journals (2016). Clinical and translational allergy, 7(46), p. 46. BioMed Central 10.1186/s13601-017-0185-4
Simon, Dagmar; Straumann, Alex; Schoepfer, Alain M; Simon, Hans-Uwe (2017). Current concepts in eosinophilic esophagitis. Allergo journal international, 26(7), pp. 258-266. Springer 10.1007/s40629-017-0037-8
Stoeckle, Christina; Geering, Barbara; Yousefi, Shida; Rožman, Saša; Andina, Nicola; Benarafa, Charaf; Simon, Hans-Uwe (2016). RhoH is a negative regulator of eosinophilopoiesis. Cell death and differentiation, 23(12), pp. 1961-1972. Nature Publishing Group 10.1038/cdd.2016.73
Bussmann, Christian; Schoepfer, Alain M; Safroneeva, Ekaterina; Haas, Nadine; Godat, Sébastien; Sempoux, Christine; Simon, Hans-Uwe; Straumann, Alex (2016). Comparison of different biopsy forceps models for tissue sampling in eosinophilic esophagitis. Endoscopy, 48(12), pp. 1069-1075. Thieme 10.1055/s-0042-117274
Amini, Poorya (2016). Optic atrophy 1 (OPA1) is essential for NET formation and antibacterial functions in neutrophils (Submitted). (Dissertation, Graduate School for Cellular and Biomedical Sciences, Faculty of Medicine, University of Bern)
Wang, Xiaoliang; Simon, Hans-Uwe; He, Zhaoyue; Liu, He; Yousefi, Shida (2016). Neutrophil Necroptosis Is Triggered by Ligation of Adhesion Molecules following GM-CSF Priming. Journal of immunology, 197(10), pp. 4090-4100. American Association of Immunologists 10.4049/jimmunol.1600051
Filipenko, Iuliia; Schwalm, Stephanie; Reali, Luca; Pfeilschifter, Josef; Fabbro, Doriano; Huwiler, Andrea; Zangemeister-Wittke, Uwe (2016). Upregulation of the S1P3 receptor in metastatic breast cancer cells increases migration and invasion by induction of PGE2 and EP2/EP4 activation. Biochimica et biophysica acta (BBA) - molecular and cell biology of lipids, 1861(11), pp. 1840-1851. Elsevier 10.1016/j.bbalip.2016.09.005
Leu, T; Rauthe, S; Wirth, C; Simon, H-U; Kunzmann, V; Hebestreit, H; Kunzmann, S; Simon, Hans-Uwe (2016). [The Lymphoid Variant of HES (L-HES) as Differential Diagnose of Severe Asthma in Childhood]. Klinische Pädiatrie, 228(06/07), pp. 319-324. Thieme 10.1055/s-0042-112593
Sudo, Makoto; Miyaji, Kazuki; Späth, Peter Julius; Morita-Matsumoto, Kana; Yamaguchi, Yoshiki; Yuki, Nobuhiro (2016). Polyclonal IgM and IgA block in vitro complement deposition mediated by anti-ganglioside antibodies in autoimmune neuropathies. International immunopharmacology, 40, pp. 11-15. Elsevier 10.1016/j.intimp.2016.08.019
Wicki, Simone; Gurzeler, Ursina; Wei-Lynn Wong, W; Bachmann, Daniel; Kaufmann, Thomas; Jost, Philipp (2016). Loss of XIAP facilitates switch to TNFα-induced necroptosis in mouse neutrophils. Cell death & disease, 7(10), e2422. Nature Publishing Group 10.1038/cddis.2016.311
Tuzlak, Selma; Kaufmann, Thomas; Villunger, Andreas (2016). Interrogating the relevance of mitochondrial apoptosis for vertebrate development and postnatal tissue homeostasis. Genes & development, 30(19), pp. 2133-2151. Cold Spring Harbor Laboratory Press 10.1101/gad.289298.116
Fernandez Marrero, Yuniel; Spinner, S; Jost, P J; Kaufmann, Thomas (2016). Survival control of malignant lymphocytes by anti-apoptotic MCL-1. Leukemia, 30(11), pp. 2152-2159. Nature Publishing Group 10.1038/leu.2016.213
Spirk, David; Aujesky, Drahomir; Stuck, Anna K; Beer, Jürg H; Mazzolai, Lucia; Baldi, Thomas; Banyai, Martin; Hayoz, Daniel; Kaeslin, Thomas; Korte, Wolfgang; Escher, Robert; Husmann, Marc; Frauchiger, Beat; Baumgartner, Iris; Kucher, Nils (2016). Clinical Outcomes of Venous Thromboembolism in Patients with and without Cancer: The SWIss Venous ThromboEmbolism Registry (SWIVTER). Seminars in thrombosis and hemostasis, 42(6), pp. 642-649. Thieme Medical Publishers 10.1055/s-0036-1584131
Kucher, Nils; Aujesky, Drahomir; Beer, Jürg H; Mazzolai, Lucia; Baldi, Thomas; Banyai, Martin; Hayoz, Daniel; Kaeslin, Thomas; Korte, Wolfgang; Escher, Robert; Husmann, Marc; Frauchiger, Beat; Baumgartner, Iris; Spirk, David (2016). Rivaroxaban for the treatment of venous thromboembolism. The SWIss Venous ThromboEmbolism Registry (SWIVTER). Thrombosis and haemostasis, 116(3), pp. 472-479. Schattauer 10.1160/TH16-03-0209
Padanad, Mahesh S; Konstantinidou, Georgia; Venkateswaran, Niranjan; Melegari, Margherita; Rindhe, Smita; Mitsche, Matthew; Yang, Chendong; Batten, Kimberly; Huffman, Kenneth E; Liu, Jingwen; Tang, Ximing; Rodriguez-Canales, Jaime; Kalhor, Neda; Shay, Jerry W; Minna, John D; McDonald, Jeffrey; Wistuba, Ignacio I; DeBerardinis, Ralph J; Scaglioni, Pier Paolo (2016). Fatty Acid Oxidation Mediated by Acyl-CoA Synthetase Long Chain 3 Is Required for Mutant KRAS Lung Tumorigenesis. Cell reports, 16(6), pp. 1614-1628. Cell Press 10.1016/j.celrep.2016.07.009
Werfel, Thomas; Allam, Jean-Pierre; Biedermann, Tilo; Eyerich, Kilian; Gilles, Stefanie; Guttman-Yassky, Emma; Hoetzenecker, Wolfram; Knol, Edward; Simon, Hans-Uwe; Wollenberg, Andreas; Bieber, Thomas; Lauener, Roger; Schmid-Grendelmeier, Peter; Traidl-Hoffmann, Claudia; Akdis, Cezmi A (2016). Cellular and molecular immunologic mechanisms in patients with atopic dermatitis. Journal of allergy and clinical immunology, 138(2), pp. 336-349. Mosby 10.1016/j.jaci.2016.06.010
Silbernagel, Günther; Spirk, David; Hager, Adrian; Baumgartner, Iris; Kucher, Nils (2016). Electronic Alert System for Improving Stroke Prevention Among Hospitalized Oral-Anticoagulation-Naïve Patients With Atrial Fibrillation: A Randomized Trial. Journal of the American Heart Association, 5(7), pp. 1-7. American Heart Association 10.1161/JAHA.116.003776
Vasilakaki, Sofia; Barbayianni, Efrosini; Magrioti, Victoria; Pastukhov, Oleksandr; Constantinou-Kokotou, Violetta; Huwiler, Andrea; Kokotos, George (2016). Inhibitors of secreted phospholipase A2 suppress the release of PGE2 in renal mesangial cells. Bioorganic & medicinal chemistry, 24(13), pp. 3029-3034. Elsevier 10.1016/j.bmc.2016.05.017
Bieber, T; Akdis, C; Lauener, R; Traidl-Hoffmann, C; Schmid-Grendelmeier, P; Schäppi, G; Allam, J-P; Apfelbacher, C; Augustin, M; Beck, L; Biedermann, T; Braun-Fahrländer, C; Chew, F T; Clavel, T; Crameri, R; Darsow, U; Deleuran, M; Dittlein, D; Duchna, H-W; Eichenfeld, L; ... (2016). Global Allergy Forum and 3rd Davos Declaration 2015: Atopic dermatitis/Eczema: challenges and opportunities toward precision medicine. Allergy, 71(5), pp. 588-592. Wiley-Blackwell 10.1111/all.12857
Muraro, Antonella; Lemanske, Robert F; Hellings, Peter W; Akdis, Cezmi A; Bieber, Thomas; Casale, Thomas B; Jutel, Marek; Ong, Peck Y; Poulsen, Lars K; Schmid-Grendelmeier, Peter; Simon, Hans-Uwe; Seys, Sven F; Agache, Ioana (2016). Precision medicine in patients with allergic diseases: Airway diseases and atopic dermatitis-PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology. Journal of allergy and clinical immunology, 137(5), pp. 1347-1358. Mosby 10.1016/j.jaci.2016.03.010
D'Orsi, Beatrice; Engel, Tobias; Pfeiffer, Shona; Nandi, Saheli; Kaufmann, Thomas; Henshall, David C; Prehn, Jochen H M (2016). Bok Is Not Pro-Apoptotic But Suppresses Poly ADP-Ribose Polymerase-Dependent Cell Death Pathways and Protects against Excitotoxic and Seizure-Induced Neuronal Injury. Journal of neuroscience, 36(16), pp. 4564-4578. Society for Neuroscience 10.1523/JNEUROSCI.3780-15.2016
Straumann, A; Blanchard, C; Radonjic-Hoesli, Susanne; Bussmann, Ch; Hruz, P; Safroneeva, Ekaterina; Simon, Dagmar; Schoepfer, A M; Simon, Hans-Uwe (2016). A new eosinophilic esophagitis (EoE)-like disease without tissue eosinophilia found in EoE Families. Allergy, 71(6), pp. 889-900. Wiley-Blackwell 10.1111/all.12879
Dhayade, Sandeep; Kaesler, Susanne; Sinnberg, Tobias; Dobrowinski, Hyazinth; Peters, Stefanie; Naumann, Ulrike; Liu, He; Hunger, Robert E.; Thunemann, Martin; Biedermann, Tilo; Schittek, Birgit; Simon, Hans-Uwe; Feil, Susanne; Feil, Robert (2016). Sildenafil Potentiates a cGMP-Dependent Pathway to Promote Melanoma Growth. Cell reports, 14(11), pp. 2599-2610. Cell Press 10.1016/j.celrep.2016.02.028
Simon, Dagmar; Cianferoni, A; Spergel, J M; Aceves, S; Holbreich, M; Venter, C; Rothenberg, M E; Terreehorst, I; Muraro, A; Lucendo, A J; Schoepfer, A; Straumann, A; Simon, Hans-Uwe (2016). Eosinophilic esophagitis is characterized by a non-IgE-mediated food hypersensitivity. Allergy, 71(5), pp. 611-620. Wiley-Blackwell 10.1111/all.12846
Metcalfe, Dean D; Pawankar, Ruby; Ackerman, Steven J; Akin, Cem; Clayton, Frederic; Falcone, Franco H; Gleich, Gerald J; Irani, Anne-Marie; Johansson, Mats W; Klion, Amy D; Leiferman, Kristin M; Levi-Schaffer, Francesca; Nilsson, Gunnar; Okayama, Yoshimichi; Prussin, Calman; Schroeder, John T; Schwartz, Lawrence B; Simon, Hans-Uwe; Walls, Andrew F and Triggiani, Massimo (2016). Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases. World Allergy Organization journal, 9, p. 7. Wolters Kluwer Health Lippincott Williams & Wilkins 10.1186/s40413-016-0094-3
Fernandez Marrero, Yuniel; Ke, Francine; Echeverry, Nohemy; Bouillet, Philippe; Bachmann, Daniel; Strasser, Andreas; Kaufmann, Thomas (2016). Is BOK required for apoptosis induced by endoplasmic reticulum stress? Proceedings of the National Academy of Sciences of the United States of America - PNAS, 113(5), E492-E493. National Academy of Sciences NAS 10.1073/pnas.1516347113
Imeri, Faik; Schwalm, Stephanie; Lyck, Ruth; Zivkovic, Aleksandra; Stark, Holger; Engelhardt, Britta; Pfeilschifter, Josef; Huwiler, Andrea (2016). Sphingosine kinase 2 deficient mice exhibit reduced experimental autoimmune encephalomyelitis: Resistance to FTY720 but not ST-968 treatments. Neuropharmacology, 105, pp. 341-350. Elsevier 10.1016/j.neuropharm.2016.01.031
Liu, He; He, Zhaoyue; Simon, Hans-Uwe (2016). The Role of Autophagy in Cancer and Chemotherapy. In: Hayat, M. (ed.) Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging. Human Diseases: Vol. 8 (pp. 253-265). Academic Press 10.1016/B978-0-12-802937-4.00014-4
Amini, Poorya; Stojkov, Darko; Wang, Xiaoliang; Wicki, Simone; Kaufmann, Thomas; Wong, Wendy Wei-Lynn; Simon, Hans-Uwe; Yousefi, Shida (2016). NET formation can occur independently of RIPK3 and MLKL signaling. European journal of immunology, 46(1), pp. 178-184. Wiley-VCH 10.1002/eji.201545615
Engert, A.; Balduini, C.; Brand, A.; Coiffier, B.; Cordonnier, C.; Dohner, H.; de Wit, T. D.; Eichinger, S.; Fibbe, W.; Green, T.; de Haas, F.; Iolascon, A.; Jaffredo, T.; Rodeghiero, F.; Salles, G.; Schuringa, J. J.; EHA, Roadmap for European Hematology Research (2016). The European Hematology Association Roadmap for European Hematology Research: a consensus document. Haematologica - the hematology journal, 101(2), pp. 115-208. Ferrata-Storti Foundation 10.3324/haematol.2015.136739
Chen, Bin; Roy, Saurabh G; McMonigle, Ryan J; Keebaugh, Andrew; McCracken, Alison N; Selwan, Elizabeth; Fransson, Rebecca; Fallegger, Daniel; Huwiler, Andrea; Kleinman, Michael T; Edinger, Aimee L; Hanessian, Stephen (2016). Azacyclic FTY720 Analogues That Limit Nutrient Transporter Expression but Lack S1P Receptor Activity and Negative Chronotropic Effects Offer a Novel and Effective Strategy to Kill Cancer Cells in Vivo. ACS Chemical Biology, 11(2), pp. 409-414. American Chemical Society 10.1021/acschembio.5b00761
Simon, Hans-Uwe; Simon, Dagmar (2016). Leserbrief zum Beitrag Hypereosinophilie. Swiss medical weekly, 16(4), p. 104. EMH Schweizerischer Ärzteverlag
Simon, Hans-Uwe; Radonjic, Susanne Irene (2016). Eosinophile Granulozyten. In: Biedermann, Tilo; Heppt, Werner; Renz, Harald; Röcken, Martin (eds.) Allergologie (pp. 77-85). Berlin, Heidelberg: Springer 10.1007/978-3-642-37203-2_7
Simon, Hans-Uwe; Tschan, Mario P.; Bütikofer, Peter (2016). Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy, 12(1), pp. 1-222. Landes Bioscience 10.1080/15548627.2015.1100356
Quast, Isaak; Keller, Christian W; Weber, Patrick; Schneider, Christoph; von Gunten, Stephan; Lünemann, Jan D (2016). Protection from experimental autoimmune encephalomyelitis by polyclonal IgG requires adjuvant-induced inflammation. Journal of neuroinflammation, 13, p. 42. BioMed Central 10.1186/s12974-016-0506-x
Simon, Hans-Uwe; Yousefi, Shida; Simon, Dagmar (2016). Basophils can form extracellular DNA traps independent of a functional NADPH oxidase. In: Maurer, Markus; Behrendt, Heidrum (eds.) Allergies: Current challenges and solutions. Proceedings of the 30th Symposium of the Collegium Internationale Allergologicum (CIA) (pp. 67-70). Ospedaletto (Pisa): Pacini editore Medicina
Carr, Tara F; Berdnikovs, Sergejs; Simon, Hans-Uwe; Bochner, Bruce S; Rosenwasser, Lanny J (2016). Eosinophilic bioactivities in severe asthma. World Allergy Organization journal, 9, p. 21. BioMed Central 10.1186/s40413-016-0112-5
Simon, Hans-Uwe; Zangemeister-Wittke, Uwe (2016). Myelosuppression. In: Schwab, Manfred (ed.) Encyclopedia of Cancer. Heidelberg: Springer
Coldewey, Sina M; Benetti, Elisa; Collino, Massimo; Pfeilschifter, Josef; Sponholz, Christoph; Bauer, Michael; Huwiler, Andrea; Thiemermann, Christoph (2016). Elevation of serum sphingosine-1-phosphate attenuates impaired cardiac function in experimental sepsis. Scientific Reports, 6, p. 27594. Nature Publishing Group 10.1038/srep27594
(2016). Protein-carbohydrate interactions in the human immune system (Submitted). (Dissertation, Graduate School for Cellular and Biomedical Sciences, University of Bern, Faculty of Medicine)
Brönnimann, Daniel; Bouchet, Audrey Michele; Schneider, Christoph; Potez, Marine Therese Charlette; Serduc, Raphaël; Bräuer-Krisch, Elke; Graber, Werner Adrian; von Gunten, Stephan; Laissue, Jean Albert; Djonov, Valentin (2016). Synchrotron microbeam irradiation induces neutrophil infiltration, thrombocyte attachment and selective vascular damage in vivo. Scientific Reports, 6(33601), p. 33601. Nature Publishing Group 10.1038/srep33601
Yousefi, Shida; Simon, Hans-Uwe (2016). NETosis - Does It Really Represent Nature's "Suicide Bomber"? Frontiers in immunology, 7(328), p. 328. Frontiers Research Foundation 10.3389/fimmu.2016.00328
Schorer, Myriam Fabiola; Simon, Dagmar (2016). Innate immune system crosstalk: Eosinophils mediate immune modulation of dendritic cells through exosomes as shuttle vectors of miRNA (Submitted). (Dissertation, Graduate School for Cellular and Biomedical Sciences, University of Bern, Faculty of Medicine)
Stojkov, Darko (2016). Actin polymerization and its glutathionylation are required for NET formation (Submitted). (Dissertation, Institute of Pharmacology, Faculty of Medicine of the University of Bern)
Filipenko, Iuliia; Huwiler, Andrea (2016). The role of the S1P3 receptor in inflammation-associated proliferative disorders (Submitted). (Dissertation, Graduate School for Cellular and Biomedical Sciences, University of Bern, Faculty of Medicine)
Reinhart, Ramona; Wicki, Simone; Kaufmann, Thomas (2016). In Vitro Differentiation of Mouse Granulocytes. Methods in molecular biology, 1419, pp. 95-107. Humana Press 10.1007/978-1-4939-3581-9_8
Wuillemin, Walter; Spirk, David; Beer, Jürg; Baumgartner, Iris (2016). Schweizer Expertenkommentare zum Update der ACCP-Guidelines. Swiss Medical Forum, 16(49-50), pp. 1059-1060. EMH Swiss Medical Publishers
Djoumerska-Alexieva, Iglika; Roumenina, Lubka; Pashov, Anastas; Dimitrov, Jordan; Hadzhieva, Maya; Lindig, Sandro; Voynova, Elisaveta; Dimitrova, Petya; Ivanovska, Nina; Bockmeyer, Clemens; Stefanova, Zvetanka; Fitting, Catherine; Bläss, Markus; Claus, Ralf; von Gunten, Stephan; Kaveri, Srini; Cavaillon, Jean-Marc; Bauer, Michael; Vassilev, Tchavdar (2015). Intravenous Immunoglobulin with Enhanced Polyspecificity Improves Survival in Experimental Sepsis and Aseptic Systemic Inflammatory Response Syndromes. Molecular medicine, 21(1), p. 1. Feinstein Institute for Medical Research 10.2119/molmed.2014.00224
Imeri, Faik; Blanchard, Olivier; Jenni, Aurelio Leandro; Schwalm, Stephanie; Wünsche, Christin; Zivkovic, Aleksandra; Stark, Holger; Pfeilschifter, Josef; Huwiler, Andrea (2015). FTY720 and two novel butterfly derivatives exert a general anti-inflammatory potential by reducing immune cell adhesion to endothelial cells through activation of S1P3 and phosphoinositide 3-kinase. Naunyn-Schmiedeberg's archives of pharmacology, 388(12), pp. 1283-1292. Springer 10.1007/s00210-015-1159-5
Merten, Hannes; Brandl, Fabian; Plückthun, Andreas; Zangemeister-Wittke, Uwe (2015). Antibody-Drug Conjugates for Tumor Targeting-Novel Conjugation Chemistries and the Promise of non-IgG Binding Proteins. Bioconjugate chemistry, 26(11), pp. 2176-2185. American Chemical Society 10.1021/acs.bioconjchem.5b00260
Leu, T; Simon, Hans-Uwe; Hebestreit, H; Kunzmann, S (2015). The Hypereosinophilic Syndromes in Childhood. Klinische Pädiatrie, 227(6-07), pp. 308-313. Thieme 10.1055/s-0035-1555792
He, Zhaoyue; Agostini, Massimiliano; Liu, He; Melino, Gerry; Simon, Hans-Uwe (2015). p73 regulates basal and starvation-induced liver metabolism in vivo. OncoTarget, 6(32), pp. 33178-33190. Impact Journals LLC 10.18632/oncotarget.5090
Yousefi, Shida; Morshed, Md. Mahbubul; Amini, Poorya; Stojkov, Darko; Simon, Dagmar; von Gunten, Stephan; Kaufmann, Thomas; Simon, Hans-Uwe (2015). Basophils exhibit antibacterial activity through extracellular trap formation. Allergy, 70(9), pp. 1184-1188. Wiley-Blackwell 10.1111/all.12662
Tiligada, Ekaterini; Ishii, Masaru; Riccardi, Carlo; Spedding, Michael; Simon, Hans-Uwe; Teixeira, Mauro Martins; Cuervo, Mario Landys Chovel; Holgate, Stephen T; Levi-Schaffer, Francesca (2015). The expanding role of immunopharmacology: IUPHAR Review 16. British journal of pharmacology, 172(17), pp. 4217-4227. Wiley-Blackwell 10.1111/bph.13219
Urtz, Nicole; Gaertner, Florian; von Bruehl, Marie-Luise; Chandraratne, Sue; Rahimi, Faridun; Zhang, Lingli; Orban, Mathias; Barocke, Verena; Beil, Johannes; Schubert, Irene; Lorenz, Michael; Legate, Kyle R; Huwiler, Andrea; Pfeilschifter, Josef M; Beerli, Christian; Ledieu, David; Persohn, Elke; Billich, Andreas; Baumruker, Thomas; Mederos y Schnitzler, Michael; ... (2015). Sphingosine 1-Phosphate Produced by Sphingosine Kinase 2 Intrinsically Controls Platelet Aggregation In Vitro and In Vivo. Circulation research, 117(4), pp. 376-387. Lippincott Williams & Wilkins 10.1161/CIRCRESAHA.115.306901
Boyman, O; Kaegi, C; Akdis, M; Bavbek, S; Bossios, A; Chatzipetrou, A; Eiwegger, T; Firinu, D; Harr, T; Knol, E; Matucci, A; Palomares, O; Schmidt-Weber, C; Simon, Hans-Uwe; Steiner, U C; Vultaggio, A; Akdis, C A; Spertini, F (2015). EAACI IG Biologicals task force paper on the use of biologic agents in allergic disorders. Allergy, 70(7), pp. 727-754. Wiley-Blackwell 10.1111/all.12616
Schwalm, Stephanie; Maneva Timcheva, Tankica; Filipenko, Iuliia; Ebadi, Mahsa; Hofmann, Lotte P; Zangemeister-Wittke, Uwe; Pfeilschifter, Josef; Huwiler, Andrea (2015). Sphingosine kinase 2 deficiency increases proliferation and migration of renal mouse mesangial cells and fibroblasts. Biological chemistry, 396(6-7), pp. 813-825. De Gruyter 10.1515/hsz-2014-0289
Schröder, Matthias; Arlt, Olga; Schmidt, Helmut; Huwiler, Andrea; Angioni, Carlo; Pfeilschifter, Josef M; Schwiebs, Anja; Radeke, Heinfried H (2015). Subcellular distribution of FTY720 and FTY720-phosphate in immune cells - another aspect of Fingolimod action relevant for therapeutic application. Biological chemistry, 396(6-7), pp. 795-802. De Gruyter 10.1515/hsz-2014-0287
Hurrell, Benjamin P; Schuster, Steffen; Grün, Eva; Coutaz, Manuel; Williams, Roderick A; Held, Werner; Malissen, Bernard; Malissen, Marie; Yousefi, Shida; Simon, Hans-Uwe; Müller, Andreas J; Tacchini-Cottier, Fabienne (2015). Rapid Sequestration of Leishmania mexicana by Neutrophils Contributes to the Development of Chronic Lesion. PLoS pathogens, 11(5), e1004929. Public Library of Science 10.1371/journal.ppat.1004929
Wünsche, Christin; Koch, Alexander; Goldschmeding, Roel; Schwalm, Stephanie; Meyer Zu Heringdorf, Dagmar; Huwiler, Andrea; Pfeilschifter, Josef (2015). Transforming growth factor β2 (TGF-β2)-induced connective tissue growth factor (CTGF) expression requires sphingosine 1-phosphate receptor 5 (S1P5) in human mesangial cells. Biochimica et biophysica acta (BBA) - molecular and cell biology of lipids, 1851(5), pp. 519-526. Elsevier 10.1016/j.bbalip.2015.01.003
Galluzzi, Lorenzo; Pietrocola, Federico; Bravo-San Pedro, José Manuel; Amaravadi, Ravi K; Baehrecke, Eric H; Cecconi, Francesco; Codogno, Patrice; Debnath, Jayanta; Gewirtz, David A; Karantza, Vassiliki; Kimmelman, Alec; Kumar, Sharad; Levine, Beth; Maiuri, Maria Chiara; Martin, Seamus J; Penninger, Josef; Piacentini, Mauro; Rubinsztein, David C; Simon, Hans-Uwe; Simonsen, Anne; ... (2015). Autophagy in malignant transformation and cancer progression. EMBO journal, 34(7), pp. 856-880. Nature Publishing Group 10.15252/embj.201490784
Simon, Dagmar; Radonjic, Susanne Irene; Straumann, A; Yousefi, Shida; Simon, Hans-Uwe (2015). Active eosinophilic esophagitis is characterized by epithelial barrier defects and eosinophil extracellular trap formation. Allergy, 70(4), pp. 443-452. Wiley-Blackwell 10.1111/all.12570
Soragni, Alice; Yousefi, Shida; Stoeckle, Christina; Soriaga, Angela B; Sawaya, Michael R; Kozlowski, Eveline; Schmid, Ines; Radonjic-Hoesli, Susanne; Boutet, Sebastien; Williams, Garth J; Messerschmidt, Marc; Seibert, M Marvin; Cascio, Duilio; Zatsepin, Nadia A; Burghammer, Manfred; Riekel, Christian; Colletier, Jacques-Philippe; Riek, Roland; Eisenberg, David S and Simon, Hans-Uwe (2015). Toxicity of eosinophil MBP is repressed by intracellular crystallization and promoted by extracellular aggregation. Molecular cell, 57(6), pp. 1011-1021. Cell Press 10.1016/j.molcel.2015.01.026
Rozman, Sasa; Yousefi, Shida; Oberson, Kevin; Kaufmann, Thomas; Benarafa, Charaf; Simon, Hans-Uwe (2015). The generation of neutrophils in the bone marrow is controlled by autophagy. Cell death and differentiation, 22(3), pp. 445-456. Nature Publishing Group 10.1038/cdd.2014.169
Koch, Alexander; Jäger, Manuel; Völzke, Anja; Grammatikos, Georgios; Zu Heringdorf, Dagmar Meyer; Huwiler, Andrea; Pfeilschifter, Josef (2015). Downregulation of sphingosine 1-phosphate (S1P) receptor 1 by dexamethasone inhibits S1P-induced mesangial cell migration. Biological chemistry, 396(6-7), pp. 803-812. De Gruyter 10.1515/hsz-2014-0288
Kaufmann, Thomas; Simon, Hans-Uwe (2015). Targeting disease by immunomodulation. Cell death and differentiation, 22(2), pp. 185-186. Nature Publishing Group 10.1038/cdd.2014.166
Liu, He; He, Zhaoyue; Simon, Hans-Uwe (2015). Protective role of autophagy and autophagy-related protein 5 in early tumorigenesis. Journal of molecular medicine JMM, 93(2), pp. 159-164. Springer 10.1007/s00109-014-1241-3
Spirk, David; Nendaz, M; Aujesky, Drahomir; Hayoz, D; Beer, J H; Husmann, M; Frauchiger, B; Korte, W; Wuillemin, Walter Alfred; Righini, M; Bounameaux, H; Kucher, Nils (2015). Predictors of thromboprophylaxis in hospitalised medical patients. Explicit ASsessment of Thromboembolic RIsk and Prophylaxis for Medical PATients in SwitzErland (ESTIMATE). Thrombosis and haemostasis, 113(5), pp. 1127-1134. Schattauer 10.1160/TH14-06-0525
Schneider, Christoph; Smith, David F; Cummings, Richard D; Frias Boligan, Kayluz; Hamilton, Robert G; Bochner, Bruce S; Miescher, Sylvia; Simon, Hans-Uwe; Pashov, Anastas; Vassilev, Tchavdar; von Gunten, Stephan (2015). The human IgG anti-carbohydrate repertoire exhibits a universal architecture and contains specificity for microbial attachment sites. Science translational medicine, 7(269), 269ra1. American Association for the Advancement of Science 10.1126/scitranslmed.3010524
Engelberger, Rolf Peter; Spirk, David; Willenberg, Torsten Andreas; Alatri, Adriano; Do, Dai-Do; Baumgartner, Iris; Kucher, Nils (2015). Ultrasound-assisted versus conventional catheter-directed thrombolysis for acute iliofemoral deep vein thrombosis. Circulation: Cardiovascular interventions, 8(1) Lippincott Williams & Wilkins 10.1161/CIRCINTERVENTIONS.114.002027
Kaufmann, Thomas; Simon, Hans-Uwe (2015). Essential versus accessory aspects of cell death: recommendations of the NCCD 2015. Cell death and differentiation, 22(1), pp. 58-73. Nature Publishing Group 10.1038/cdd.2014.137
Radonjic-Hoesli, Susanne; Valent, Peter; Klion, Amy D; Wechsler, Michael E; Simon, Hans-Uwe (2015). Novel targeted therapies for eosinophil-associated diseases and allergy. Annual review of pharmacology and toxicology, 55(1), pp. 633-656. Annual Reviews Inc. 10.1146/annurev-pharmtox-010814-124407
de Graauw, Elisabeth Louisa; Beltraminelli, Helmut; Simon, Hans-Uwe; Simon, Dagmar (2015). Eosinophilia in Dermatologic Disorders. Immunology and allergy clinics of North America, 35(3), pp. 545-560. Elsevier 10.1016/j.iac.2015.05.005
Simon, Hans-Uwe (2015). Regulation of inflammation by cell death in allergic rhinitis. In: Akdis, Cezmi A.; Hellings, Peter W. (eds.) Global Atlas of Allergic Rhinitis and chronic rhinosinusitis (pp. 43-44). European Academy of Allergy and Clinical Immunology
Geering, Barbara; Zokouri, Zina; Hürlemann, Samuel; Gerrits, Bertran; Ausländer, David; Britschgi, Adrian; Tschan, Mario; Simon, Hans-Uwe; Fussenegger, Martin (2015). Identification of Novel Death-Associated Protein Kinase 2 Interaction Partners by Proteomic Screening Coupled with Bimolecular Fluorescence Complementation. Molecular and cellular biology, 36(1), pp. 132-143. American Society for Microbiology 10.1128/MCB.00515-15
Kaufmann, Thomas; Reinhart, Ramona; Wicki, Simone (2015). In vitro differentiation of mouse granulocytes. Programmed Cell Death: Methods and Protocols (In Press). In: Puthalakath, Hamsa; Hawkins, Christine (eds.) Programmed Cell Death: Methods and Protocols. Methods in Molecular Biology. Humana Press
Cortinas-Elizondo, F.; von Gunten, Stephan (2015). MicroRNA-155: microtuning the allergic concert. Allergy, 70(9), pp. 1035-1036. Wiley-Blackwell 10.1111/all.12673
Späth, Peter Julius; Granata, Guido; La Marra, Fabiola; Kuijpers, Taco W.; Quinti, Isabella (2015). On the Dark Side of Therapies with Immunoglobulin Concentrates: The Adverse Events. Frontiers in immunology, 6(11), p. 11. Frontiers Research Foundation 10.3389/fimmu.2015.00011
Riebenfeld, Daniela; Spirk, David; Mathis, Alexandra; Villiger, Lukas; Gerber, Philipp A; Gasser, Urs Erwin; Lehmann, Roger (2015). Treatment intensification with insulin glargine in patients with inadequately controlled type 2 diabetes improves glycaemic control with a high treatment satisfaction and no weight gain. Swiss medical weekly, 145, w14114. EMH Schweizerischer Ärzteverlag 10.4414/smw.2015.14114
Maier, Larissa J; Liakoni, Evangelia; Schildmann, Jan; Schaub, Michael P; Liechti, Matthias E (2015). Swiss University Students' Attitudes toward Pharmacological Cognitive Enhancement. PLoS ONE, 10(12), e0144402. Public Library of Science 10.1371/journal.pone.0144402
Liakoni, Evangelia; Schaub, Michael P; Maier, Larissa J; Glauser, Gaëlle-Vanessa; Liechti, Matthias E (2015). The Use of Prescription Drugs, Recreational Drugs, and "Soft Enhancers" for Cognitive Enhancement among Swiss Secondary School Students. PLoS ONE, 10(10), e0141289. Public Library of Science 10.1371/journal.pone.0141289
Ramadori, Giorgio; Konstantinidou, Georgia; Venkateswaran, Niranjan; Biscotti, Tommasina; Morlock, Lorraine; Galié, Mirco; Williams, Noelle S.; Luchetti, Michele; Santinelli, Alfredo; Scaglioni, Pier Paolo; Coppari, Roberto (2015). Diet-Induced Unresolved ER Stress Hinders KRAS-Driven Lung Tumorigenesis. Cell metabolism, 21(1), pp. 117-125. Cell Press 10.1016/j.cmet.2014.11.020
Gaubitz, Christl; Oliveira, Taiana M.; Prouteau, Manoel; Leitner, Alexander; Karuppasamy, Manikandan; Konstantinidou, Georgia; Rispal, Delphine; Eltschinger, Sandra; Robinson, Graham C.; Thore, Stéphane; Aebersold, Ruedi; Schaffitzel, Christiane; Loewith, Robbie (2015). Molecular Basis of the Rapamycin Insensitivity of Target Of Rapamycin Complex 2. Molecular cell, 58(6), pp. 977-988. Cell Press 10.1016/j.molcel.2015.04.031
Kerr, Jacqueline; Quinti, Isabella; Eibl, Martha; Chapel, Helen; Späth, Peter Julius; Sewell, W A Carrock; Salama, Abdulgabar; van Schaik, Ivo N; Kuijpers, Taco W; Peter, Hans-Hartmut (2014). Is dosing of therapeutic immunoglobulins optimal? A review of a three-decade long debate in europe. Frontiers in immunology, 5(629), p. 629. Frontiers Research Foundation 10.3389/fimmu.2014.00629
Wehrli, Marc; Cortinas-Elizondo, Fabiola; Hlushchuk, Ruslan; Daudel, Fritz; Villiger, Peter M.; Miescher, Sylvia; Zuercher, Adrian W.; Djonov, Valentin; Simon, Hans-Uwe; von Gunten, Stephan (2014). Human IgA Fc receptor FcαRI (CD89) triggers different forms of neutrophil death depending on the inflammatory microenvironment. Journal of immunology, 193(11), pp. 5649-5659. American Association of Immunologists 10.4049/jimmunol.1400028
Pastukhov, Oleksandr; Schalm, Stephanie; Zangemeister-Wittke, Uwe; Fabbro, Doriano; Bornancin, Frederic; Japtok, Lukasz; Kleuser, Burkhrad; Pfeilschifter, Josef; Huwiler, Andrea (2014). The ceramide kinase inhibitor NVP-231 inhibits breast and lung cancer cell proliferation by inducing M phase arrest and subsequent cell death. British journal of pharmacology, 171(24), pp. 5829-5844. Wiley-Blackwell 10.1111/bph.12886
von Gunten, Stephan (2014). Protein-glycan interactions as targets of intravenous/subcutaneous immunoglobulin (IVIg/SCIg) preparations. Clinical and experimental immunology, 178(S1), pp. 151-152. Blackwell Scientific Publications 10.1111/cei.12550
Frias Boligan, Kayluz; Mesa, Circe; Fernandez, Luis Enrique; von Gunten, Stephan (2014). Cancer intelligence acquired (CIA): tumor glycosylation and sialylation codes dismantling antitumor defense. Cellular and molecular life sciences, 72(7), pp. 1231-1248. Springer 10.1007/s00018-014-1799-5
Liu, He; He, Zhaoyue; Simon, Hans-Uwe (2014). Autophagy suppresses melanoma tumorigenesis by inducing senescence. Autophagy, 10(2), pp. 372-373. Landes Bioscience 10.4161/auto.27163
Stefan, Nikolas; Zimmermann, Martina; Simon, Manuel; Zangemeister-Wittke, Uwe; Plückthun, Andreas (2014). Novel Prodrug-Like Fusion Toxin with Protease-Sensitive Bioorthogonal PEGylation for Tumor Targeting. Bioconjugate chemistry, 25(12), pp. 2144-2156. American Chemical Society 10.1021/bc500468s
Imeri, Faik; Fallegger, Daniel; Zivkovic, Aleksandra; Schwalm, Stephanie; Enzmann, Gaby; Blankenbach, Kira; Meyer zu Heringdorf, Dagmar; Homann, Thomas; Kleuser, Burkhard; Pfeilschifter, Josef; Engelhardt, Britta; Stark, Holger; Huwiler, Andrea (2014). Novel oxazolo-oxazole derivatives of FTY720 reduce endothelial cell permeability, immune cell chemotaxis and symptoms of experimental autoimmune encephalomyelitis in mice. Neuropharmacology, 85, pp. 314-327. Elsevier 10.1016/j.neuropharm.2014.05.012
Sudo, Makoto; Yamaguchi, Yoshiki; Späth, Peter Julius; Matsumoto-Morita, Kana; Ong, Benjamin K.; Shahrizaila, Nortina; Yuki, Nobuhiro (2014). Different IVIG glycoforms affect in vitro inhibition of anti-ganglioside antibody-mediated complement deposition. PLoS ONE, 9(9), e107772. Public Library of Science 10.1371/journal.pone.0107772
Haimovici, Aladin; Brigger, Daniel; Torbett, Bruce E; Fey, Martin; Tschan, Mario (2014). Induction of the autophagy-associated gene MAP1S via PU.1 supports APL differentiation. Leukemia research, 38(9), pp. 1041-1047. Elsevier 10.1016/j.leukres.2014.06.010
de Graauw, Elisabeth Louisa; Sitaru, C.; Borradori, Luca; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (September 2014). The pathogenic role of neutrophils, eosinophils and peripheral blood mononuclear cells (PBMC's) in bullous pemphigoid. Dermatologica Helvetica, 26(6). Karger
Sewell, W. A. Carrock; Kerr, Jacqueline; Behr-Gross, Marie-Emmanuelle; Peter, Hans-Hartmut; Kreuth Ig Working Group, ; Späth, Peter Julius (2014). European consensus proposal for immunoglobulin therapies. European journal of immunology, 44(8), pp. 2207-2214. Wiley-VCH
Thangaiyan, Rabi; Huwiler, Andrea; Zangemeister-Wittke, Uwe (2014). AMR-Me inhibits PI3K/Akt signaling in hormone-dependent MCF-7 breast cancer cells and inactivates NF-κB in hormone-independent MDA-MB-231 cells. Molecular carcinogenesis, 53(7), pp. 578-588. Wiley 10.1002/mc.22012
Späth, Peter Julius; Tamburin, Stefano; Borg, Christian; Caro, Xavier J.; Jann, Stefano; Clark, Alexander J.; Maginelli, Francesca; Sobue, Gen; Werhagen, Lars; Zanetta, Giampietro; Koike, Haruki; Vincent, Angela; Goebel, Andreas (2014). Immunoglobulin g for the treatment of chronic pain: report of an expert workshop. Pain medicine, 15(7), pp. 1072-1082. Wiley-Blackwell 10.1111/pme.12319
Andree, Maria; Seeger, Jens M.; Schüll, Stephan; Coutelle, Oliver; Wagner-Stippich, Diana; Wiegmann, Katja; Wunderlich, Claudia M.; Birkmann, Kerstin; Broxtermann, Pia; Witt, Axel; Fritsch, Melanie; Martinelli, Paola; Bielig, Harald; Lamkemeyer, Tobias; Rugarli, Elena I.; Kaufmann, Thomas; Sterner-Kock, Anja; Wunderlich, F. Thomas; Villunger, Andreas; Martins, L. Miguel; ... (2014). BID-dependent release of mitochondrial SMAC dampens XIAP-mediated immunity against Shigella. EMBO journal, 33(19), pp. 2171-2187. Nature Publishing Group 10.15252/embj.201387244
Morshed, Md. Mahbubul; Hlushchuk, Ruslan; Simon, Dagmar; Walls, Andrew F.; Obata-Ninomiya, Kazushige; Karasuyama, Hajime; Djonov, Valentin; Eggel, Alexander; Kaufmann, Thomas; Simon, Hans-Uwe; Yousefi, Shida (2014). NADPH oxidase-independent formation of extracellular DNA traps by basophils. Journal of immunology, 192(11), pp. 5314-5323. American Association of Immunologists 10.4049/jimmunol.1303418
Imeri, Faik; Jashri, Ahmed; Bullazhi, Lulzime; Shabani, Agim; Mikhova, Bozhana; Dräger, Gerald; Popovski, Emil; Huwiler, Andrea (2014). Synthesis and cellular characterization of novel isoxazolo- and thiazolohydrazinylidene-chroman-2,4-diones on cancer and non-cancer cell growth and death. Bioorganic & medicinal chemistry, 22(9), pp. 2655-2660. Elsevier 10.1016/j.bmc.2014.03.026
Stowell, Sean R.; Arthur, Connie M.; Mc Bride, Ryan; Berger, Oren; Razi, Nahid; Heimberg-Molinaro, Jamie; Rodrigues, Lilian C.; Gourdine, Jean-Philippe; Noll, Alexander J.; von Gunten, Stephan; Smith, David F.; Knirel, Yuriy A.; Paulson, James C.; Cummings, Richard D. (2014). Microbial glycan microarrays define key features of host-microbial interactions. Nature Chemical Biology, 10(6), pp. 470-476. Nature Publishing Group 10.1038/nchembio.1525
Simon, Dagmar; Straumann, A.; Simon, Hans-Uwe (2014). Eosinophilic esophagitis and allergy. Digestive diseases, 32(1-2), pp. 30-33. Karger 10.1159/000357006
von Gunten, Stephan (2014). Targeting Siglecs: Neue potenzielle Strategien zur Immuntherapie entzündlicher oder maligner Erkrankungen. Leading Opinions. Hämatologie & Onkologie(2), pp. 34-36. Universimed
Geering, Barbara; Stoeckle, Christina; Rozman, Sasa; Oberson, Kevin; Benarafa, Charaf; Simon, Hans-Uwe (2014). DAPK2 positively regulates motility of neutrophils and eosinophils in response to intermediary chemoattractants. Journal of leukocyte biology, 95(2), pp. 293-303. Society for Leukocyte Biology 10.1189/jlb.0813462
Simon, D.; Aeberhard, C.; Erdemoglu, Y.; Simon, H.-U. (2014). Th17 cells and tissue remodeling in atopic and contact dermatitis. Allergy, 69(1), pp. 125-131. Wiley-Blackwell 10.1111/all.12351
Humbert, Magali; Federzoni, Elena; Britschgi, Adrian; Schläfli, Anna; Valk, PJ; Kaufmann, Thomas; Haferlach, T.; Behre, G.; Simon, Hans-Uwe; Torbett, BE; Fey, Martin; Tschan, Mario (2014). The tumor suppressor gene DAPK2 is induced by the myeloid transcription factors PU.1 and C/EBPα during granulocytic differentiation but repressed by PML-RARα in APL. Journal of leukocyte biology, 95(1), pp. 83-93. Society for Leukocyte Biology 10.1189/jlb.1112608
Simon, Manuel; Stefan, Nikolas; Borsig, Lubor; Plückthun, Andreas; Zangemeister-Wittke, Uwe (2014). Increasing the Antitumor Effect of an EpCAM-Targeting Fusion Toxin by Facile Click PEGylation. Molecular cancer therapeutics, 2(13), pp. 375-385. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-13-0523
Schwalm, Stephanie; Pfeilschifter, Josef; Huwiler, Andrea (2014). Targeting the sphingosine kinase/sphingosine 1-phosphate pathway to treat chronic inflammatory kidney diseases. Basic & clinical pharmacology & toxicology, 1(114), pp. 44-49. Wiley-Blackwell 10.1111/bcpt.12103
Weber, Benjamin; Schuster, Steffen; Zysset, Daniel; Rihs, Silvia; Dickgreber, Nina; Schürch, Christian; Riether, Carsten; Siegrist, Mark; Schneider, Christoph; Pawelski, Helga; Gurzeler, Ursina; Ziltener, Pascal; Genitsch, Vera; Tacchini-Cottier, Fabienne; Ochsenbein, Adrian; Hofstetter, Willy; Kopf, Manfred; Kaufmann, Thomas; Oxenius, Annette; Reith, Walter; ... (2014). TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance. PLoS pathogens, 10(1), e1003900. Public Library of Science 10.1371/journal.ppat.1003900
Völzke, Anja; Koch, Alexander; Meyer zu Heringdorf, Dagmar; Huwiler, Andrea; Pfeilschifter, Josef (2014). Sphingosine 1-phosphate (S1P) induces COX-2 expression and PGE2 formation via S1P receptor 2 in renal mesangial cells. Biochimica and biophysica acta - molecular and cell biology of lipids, 1841(1), pp. 11-21. Elsevier 10.1016/j.bbalip.2013.09.009
Simon, Hans-Uwe; Friis, Robert (2014). ATG5: a distinct role in the nucleus. Autophagy, 10(1), pp. 176-177. Landes Bioscience 10.4161/auto.26916
Simon, Hans-Uwe; Straumann, Alex (2014). Immunopathogenesis of eosinophilic esophagitis. Digestive diseases, 32(1-2), pp. 11-14. Karger 10.1159/000357003
Houriet, C.; Simon, H.-U.; Simon, D. (2014). Hypereosinophilic Syndromes. Aktuelle Dermatologie, 40(4), pp. 127-132. Thieme 10.1055/s-0034-1365078
Radonjic-Hösli, Susanne; Simon, Hans-Uwe (2014). Eosinophils. Chemical immunology and allergy, 100, pp. 193-204. Karger 10.1159/000358735
Simon, Hans-Uwe (2014). Eosinophils. In: Global Atlas of Allergy (pp. 58-59). Zurich: EAACI
Yabal, Monica; Müller, Nicole; Adler, Heiko; Knies, Nathalie; Gross, Christina J.; Damgaard, Rune Busk; Kanegane, Hirokazu; Ringelhan, Marc; Kaufmann, Thomas; Heikenwächter, Mathias; Strasser, Andreas; Gross, Olaf; Ruland, Jürgen; Peschel, Christian; Gyrd-Hansen, Mads; Jost, Philipp J. (2014). XIAP Restricts TNF- and RIP3-Dependent Cell Death and Inflammasome Activation. Cell reports, 7(6), pp. 1795-1808. Cell Press 10.1016/j.celrep.2014.05.008
Simon, Hans-Uwe; Yousefi, Shida; Schmid, Ines; Friis, Robert (2014). ATG5 can regulate p53 expression and activation. Cell death & disease, 5(e1339), pp. 176-177. Nature Publishing Group 10.1038/cddis.2014.308
Ring, J.; Akdis, C.; Lauener, R.; Schäppi, G.; Traidl-Hoffmann, C.; Akdis, M.; Ammann, W.; Behrendt, H.; Bieber, T.; Biedermann, T.; Bienenstock, J.; Blaser, K.; Braun-Fahrländer, C.; Brocknow, K.; Buters, J.; Crameri, R.; Darsow, U.; Denburg, J.A.; Eyerich, K.; Frei, R.; ... (2014). Global Allergy Forum and Second Davos Declaration 2013 Allergy: Barriers to cure - challenges and actions to be taken. Allergy, 69(8), pp. 978-982. Wiley-Blackwell 10.1111/all.12406
von Gunten, Stephan; Shoenfeld, Yehuda; Blank, Miri; Branch, Donald R.; Vassoöev, Tchavdar; Käsermann, Fabian; Bayy, Jagadeesh; Kaveri, Srini; Simon, Hans-Uwe (2014). IVIG pluripotency and the concept of Fc-sialylation: challenges to the scientist. Nature reviews - immunology, 14(5), pp. 349-350. Nature Publishing Group 10.1038/nri3401-c1
Jandus, Camilla; Frias Boligan, Kayluz; Chijioke, Obinna; Liu, He; Dahlhaus, Meike; Demoulins, Thomas; Schneider, Christoph; Wehrli, Marc; Hunger, Robert E.; Baerlocher, Gabriela M.; Simon, Hans-Uwe; Romero, Pedro; Münz, Christian; von Gunten, Stephan (2014). Interactions between Siglec-7/9 receptors and ligands influence NK cell-dependent tumor immunosurveillance. Journal of clinical investigation, 124(4), pp. 1810-1820. American Society for Clinical Investigation 10.1172/JCI65899
Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (2014). Eosinophil extracellular traps: potential role(s) in eosinophilic diseases. In: Galli, Stephen J.; You-Young, Kim (eds.) Allergic Diseases: from Mechanisms to Cures. Proceedings of the 29th Symposium of the Collegium Internationale Allergologicum. Allergologia e immunologia (pp. 87-89). Pisa: Pacini Editore S.p.A.
Simon, Dagmar; Simon, Hans-Uwe; Yousefi, Shida (2014). Eosinophil extracellular trap formation in response to thymic stromal lymphopoietin stimulation. In: Galli, Stephen J.; You-Young, Kim (eds.) Allergic Diseases: from mechanisms to cures. Proceedings of the 29th Symposium of the Collegium Internationale Allergologicum. Allergologia e immunologia (pp. 83-86). Pisa: Pacini Editore
Späth, Peter Julius (2014). A novel use of intravenous immunoglobulin is not restricted to complement hypercatabolism because of factor H deficiency. Progress in transplantation, 24(2), p. 120. InnoVision Communications 10.7182/pit2014750
Späth, Peter Julius (2014). Report from a rare diseases event in Targu Mures, Romania. Romanian Review of Laboratory Medicine, 22(3), pp. 397-398. Romanian Association of Medical Laboratories
Späth, Peter Julius (2014). A glance on recent progresses in diagnosis and treatment of primary immunodeficiencies. Romanian Review of Laboratory Medicine, 22(3), pp. 297-309. Romanian Association of Medical Laboratories 10.2478/rrlm-2014-0034
Späth, Peter Julius (2014). Report on Congress Highlights 2013. Congress Report 2013.
Kondo, Shunya; Bottos, Alessia; Allegood, Jeremy C.; Masson, Regis; Maurer, Francisca G.; Genoud, Christel; Kaeser, Patrick; Huwiler, Andrea; Murakami, Masato; Spiegel, Sarah; Hynes, Nancy E. (2014). Memo has a novel role in S1P signaling and crucial for vascular development. PLoS ONE, 9(4), e94114. Public Library of Science 10.1371/journal.pone.0094114
Pastukhov, Oleksandr; Schalm, Stephanie; Römer, Isolde; Pfeilschifter, Josef; Huwiler, Andrea; Zangemeister-Wittke, Uwe (2014). Ceramide kinase contributes to proliferation but not to prostaglandin E2 formation in renal mesangial cells and fibroblasts. Cellular physiology and biochemistry, 34(1), pp. 119-133. Karger 10.1159/000362989
Simon, Hans-Uwe (2014). IL17, IL22 and tissue remodeling in atopic and contact dermatitis. In: Maurer, Marcus; Behrendt, Heidrun (eds.) Allergies: Current challenges and solutions (pp. 183-186). Paccini editore medicina
Schoepfer, Alain M.; Safroneeva, Ekaterina; Bussmann, Christian; Kuchen, Tanja; Portmann, Susanne; Simon, Hans-Uwe; Straumann, Alex (2013). Delay in diagnosis of eosinophilic esophagitis increases risk for stricture formation in a time-dependent manner. Gastroenterology, 145(6), 1230-1236.e2. Elsevier 10.1053/j.gastro.2013.08.015
Simon, Dagmar; Borradori, Luca; Simon, Hans-Uwe (2013). Glucocorticoids in autoimmune bullous diseases: are neutrophils the key cellular target? Journal of Investigative Dermatology, 133(10), pp. 2314-2315. Nature Publishing 10.1038/jid.2013.205
Herold, Marco J.; Rohrbeck, Leona; Lang, Mathias J.; Grumont, Raelene; Gerondakis, Steve; Tai, Lin; Bouillet, Philippe; Kaufmann, Thomas; Strasser, Andreas (2013). Foxo-mediated Bim transcription is dispensable for the apoptosis of hematopoietic cells that is mediated by this BH3-only protein. EMBO REPORTS, 14(11), pp. 992-998. Nature 10.1038/embor.2013.152
Stoeckle, Christina; Rota, Ioanna A.; Tolosa, Eva; Haller, Christoph; Melms, Arthur; Adamopoulou, Eleni (2013). Isolation of myeloid dendritic cells and epithelial cells from human thymus. Journal of visualized experiments, 79(79), e50951. MYJoVE Corporation 10.3791/50951
Geering, Barbara; Stoeckle, Christina; Conus, Sébastien; Simon, Hans-Uwe (2013). Living and dying for inflammation: neutrophils, eosinophils, basophils. Trends in immunology, 34(8), pp. 398-409. Elsevier Current Trends 10.1016/j.it.2013.04.002
Schulman, Jacqualyn J; Wright, Fiorrest A; Kaufmann, Thomas; Wojcikiewicz, Richard J H (2013). The Bcl-2 Protein Family Member Bok Binds to the Coupling Domain of Inositol 1,4,5-Trisphosphate Receptors and Protects Them from Proteolytic Cleavage. Journal of biological chemistry, 288(35), pp. 25340-25349. American Society for Biochemistry and Molecular Biology 10.1074/jbc.M113.496570
He, Z.; Simon, H. U. (2013). Autophagy protects from liver injury. Cell death and differentiation, 20(7), pp. 850-851. Nature Publishing Group 10.1038/cdd.2013.43
Ke, Francine; Kaufmann, Thomas; Bouillet, Philippe; Strasser, Andreas; Kerr, Jeffrey; Voss, Anne K (2013). Consequences of the combined loss of BOK and BAK or BOK and BAX. Cell death & disease, 4(6), e650. Nature Publishing Group 10.1038/cddis.2013.176
Adamopoulou, Eleni; Tenzer, Stefan; Hillen, Nina; Klug, Paul; Rota, Ioanna A.; Tietz, Silvia; Gebhardt, Madlen; Stevanovic, Stefan; Schild, Hansjörg; Tolosa, Eva; Melms, Arthur; Stoeckle, Christina (2013). Exploring the MHC-peptide matrix of central tolerance in the human thymus. Nature communications, 4(2039), p. 2039. Nature Publishing Group 10.1038/ncomms3039
Simon, Dagmar; Simon, Hans-Uwe; Yousefi, Shida (2013). Extracellular DNA traps in allergic, infectzious, and autoimmune diseases. Allergy, 68(4), pp. 409-416. Wiley-Blackwell 10.1111/all.12111
Straumann, A.; Hoesli, S.; Bussmann, Ch.; Stuck, M.; Perkins, M.; Collins, L. P.; Payton, M.; Pettipher, R.; Hunter, M.; Steiner, J.; Simon, H.-U. (2013). Anti-eosinophil activity and clinical efficacy of the CRTH2 antagonist OC000459 in eosinophilic esophagitis. Allergy, 68(3), pp. 375-385. Wiley-Blackwell 10.1111/all.12096
Echeverry, Nohemy; Bachmann, Daniel; Ke, Francine; Strasser, Andreas; Simon, Hans-Uwe; Kaufmann, Thomas (2013). Intracellular localization of the BCL-2 family member BOK and functional implications. Cell death and differentiation, 20(6), pp. 785-799. Nature Publishing Group 10.1038/cdd.2013.10
He, Zhaoyue; Simon, Hans-Uwe (2013). A novel link between p53 and ROS. Cell Cyle, 12(2), pp. 201-202. Landes Bioscience 10.4161/cc.23418
Wojtalla, Anna; Fischer, Barbara; Kotelevets, Nataliya; Mauri, Francesco A; Sobek, Jens; Rehrauer, Hubert; Wotzkow, Carlos; Tschan, Mario P; Seckl, Michael J; Zangemeister-Wittke, Uwe; Arcaro, Alexandre (2013). Targeting the phosphoinositide 3-kinase p110-α isoform impairs cell proliferation, survival, and tumor growth in small cell lung cancer. Clinical cancer research, 19(1), pp. 96-105. Philadelphia, Pa.: American Association for Cancer Research 10.1158/1078-0432.CCR-12-1138
von Gunten, Stephan; Wehrli, Marc; Simon, Hans-Uwe (2013). Cell death in immune thrombocytopenia: novel insights and perspectives. Seminars in hematology, 1(50), pp. 109-115. W.B. Saunders 10.1053/j.seminhematol.2013.03.016
Démoulins, Thomas; Bassi, Isabelle; Thomann-Harwood, Lisa; Jandus, Camilla; Simon, Hans-Uwe; von Gunten, Stephan; Mc Cullogh, Kenneth C (2013). Alginate-coated chitosan nanogel capacity to modulate the effect of TLR ligands on blood dendritic cells. Nanomedicine-Nanotechnology Biology and Medicine, 9(6), pp. 806-817. Elsevier 10.1016/j.nano.2013.01.002
von Gunten, Stephan; Schorer, Myriam Fabiola; Kollarik, M.; Beisswenger, C.; Lepper, P. M. (2013). Mechanisms and potential therapeutic targets in allergic inflammation: recent insights. Allergy, 68(12), pp. 1487-1498. Wiley-Blackwell 10.1111/all.12312
Bhabak, Krishna P.; Kleuser, Burkhard; Huwiler, Andrea; Arenz, Christoph (2013). Effective inhibition of acid and neutral ceramidases by novel B-13 and LCL-464 analogues. Bioorganic & medicinal chemistry, 21(4), pp. 874-882. Elsevier 10.1016/j.bmc.2012.12.014
Koch, Alexander; Völzke, Anja; Puff, Bianca; Blankenbach, Kira; Meyer zu Heringdorf, Dagmar; Huwiler, Andrea; Pfeilschifter, Josef (2013). PARγ agonists upregulate sphingosine 1-phosphate (S1P) receptor 1 expression, which in turn reduces S1P-induced [Ca(2+)]i increases in renal mesangial cells. Biochimica and biophysica acta - molecular and cell biology of lipids, 1831(11), pp. 1634-1643. Elsevier 10.1016/j.bbalip.2013.07.011
Albinet, V.; Bats, M-L; Huwiler, Andrea; Rochaix, P.; Chevreau, C.; Ségui, B.; Levande, T.; Andrieu-Abadie, N. (2013). Dual role of sphingosine kinase-1 in promoting the differentiation of dermal fibroblasts and the dissemination of melanoma cells. Oncogene, 33(26), pp. 3364-3373. Nature Publishing Group 10.1038/onc.2013.303
Schwlam, Stephanie; Pfeilschifter, Josef; Huwiler, Andrea (2013). Sphingosine-1-phosphate: a Janus-faced mediator of fibrotic diseases. Biochimica and biophysica acta - molecular and cell biology of lipids, 1831(1), pp. 239-250. Elsevier 10.1016/j.bbalip.2012.07.022
Koch, Alexander; Pfeilschrifter, Josef; Huwiler, Andrea (2013). Sphingosine 1-phosphate in renal diseases. Cellular physiology and biochemistry, 31(6), pp. 745-760. Karger 10.1159/000350093
Simon, Manuel; Frey, Raphael; Zangemeister-Wittke, Uwe; Plückthun, Andreas (2013). Orthogonal assembly of a designed ankyrin repeat protein-cytotoxin conjugate with a clickable serum albumin module for half-life extension. Bioconjugate chemistry, 24(11), pp. 1955-1986. American Chemical Society 10.1021/bc4004102
Simon, Manuel; Stefan, Nikolas; Plückthun, Andreas; Zangemeister-Wittke, Uwe (2013). Epithelial cell adhesion molecule-targeted drug delivery for cancer therapy. Expert opinion on drug delivery, 10(4), pp. 451-468. Taylor & Francis 10.1517/17425247.2013.759938
Walter, Stephen D.; Riddell, Corinne A.; Rabachini, Tatiana; Villa, Luisa L.; Franco, Eduardo L. (2013). Accuracy of p53 codon 72 polymorphism status determined by multiple laboratory methods: a latent class model analysis. PLoS ONE, 8(2), e56430. Public Library of Science 10.1371/journal.pone.0056430
Hajj, Glaucia N. M.; Arantes, Camilla P.; Dias, Marcos Vinicios; Roffé, Martin; Silva, Bruno Costa; Lopes, Marilene H.; Porto-Carreiro, Isabel; Rabachini de Almeida, Tatiana; Lima, Flavia R.; Beraldo, Flavio H.; Prado, Marco M. A.; Linden, Rafael; Martins, Vilma R. (2013). The unconventional secretion of stress-inducible protein 1 by a heterogeneous population of extracellular vesicles. Cellular and molecular life sciences, 70(17), pp. 3211-3227. Springer 10.1007/s00018-013-1328-y
Chevarie-Davis, M.; Ramanakumar, A. V.; Ferenczy, A.; Villa, L. L.; Franco, E. L.; Rabachini de Almeida, Tatiana (2013). Assessment of the performance of algorithms for cervical cancer screening: evidence from the Ludwig-McGill cohort study. Gynecologic oncology, 128(3), pp. 415-419. Elsevier 10.1016/j.ygyno.2012.12.008
Rabachini de Almeida, Tatiana; Oliveira, LB; Louvanto, K; Ramanakumar, AV; Franco, EL; Villa, L.L. (2013). Polymorphism in the promoter region of the Toll-like receptor 9 gene and cervical human papillomavirus infection. Journal of general virology, 94(8), pp. 1858-1864. Society for General Microbiology 10.1099/vir.0.052811-0
Stoeckle, C.; Simon, Hans-Uwe (2013). CD8(+) T cells producing IL-3 and IL-5 in non-IgE-mediated eosinophilic diseases. Allergy, 68(12), pp. 1622-1628. Wiley-Blackwell 10.1111/all.12311
Simon, D.; Straumann, A.; Dahinden, C.; Simon, H.-U. (2013). Frequent sensitization to Candida albicans and profilins in adult eosinophilic esophagitis. Allergy, 68(7), pp. 945-948. Wiley-Blackwell 10.1111/all.12157
He, Zhaoyue; Liu, He; Agostini, M.; Yousefi, Shida; Perren, Aurel; Tschan, Mario; Mak, TW; Melino, G:; Simon, Hans-Uwe (2013). p73 regulates autophagy and hepatocellular lipid metabolism through a transcriptional activation of the ATG5 gene. Cell death and differentiation, 20(10), pp. 1415-1424. Nature Publishing Group 10.1038/cdd.2013.104
Maskey, Dipak; Yousefi, Shida; Schmid, Ines; Zlobec, Inti; Perren, Aurel; Friis, Robert; Simon, Hans-Uwe (2013). ATG5 is induced by DNA-damaging agents and promotes mitotic catastrophe independent of autophagy. Nature communications, 4(1), p. 2130. Nature Publishing Group 10.1038/ncomms3130
Liu, He; He, Zhaoyue; von Rütte, Thomas; Yousefi, Shida; Hunger, Robert E.; Simon, Hans-Uwe (2013). Down-regulation of autophagy-related protein 5 (ATG5) contributes to the pathogenesis of early-stage cutaneous melanoma. Science translational medicine, 5(202), 202ra123. American Association for the Advancement of Science 10.1126/scitranslmed.3005864
Liu, He; He, Zhaoyue; Simon, Hans-Uwe (2013). Targeting autophagy as a potential therapeutic approach for melanoma therapy. Seminars in Cancer Biology, 5(23), pp. 352-360. Elsevier 10.1016/j.semcancer.2013.06.008
Henzi, Anna; Porz, Nicole; Widmer, Hans Rudolf; Di Santo, Stefano (2013). EPC secretome promotes neurogenesis in rat brain: New tool for brain repair? In: Annual Meeting of the Department of Clinical Research. Bern.
Simon, Dagmar; Simon, Hans-Uwe (2013). Eosinophilic skin diseases. In: Lee, James J.; Rosenberg, Helene F. (eds.) Eosinophils in health and diseases (pp. 442-448). Amsterdam: Elsevier
Worni, Mathias; Güller, Ulrich; White, Rebekah R.; Castleberry, Anthony W.; Pietrobon, Ricardo; Cerny, Thomas; Gloor, Beat; Köberle, Dieter (2013). Modest Improvement in Overall Survival for Patients With Metastatic Pancreatic Cancer. Pancreas, 42(7), pp. 1157-1163. Lippincott Williams & Wilkins 10.1097/MPA.0b013e318291fbc5
Konstantinidou, Georgia; Ramadori, Giorgio; Torti, Francesca; Kangasniemi, Kim; Ramirez, Rachel E.; Cai, Yiran; Behrens, Carmen; Dellinger, Michael T.; Brekken, Rolf A.; Wistuba, Ignacio I.; Heguy, Adriana; Teruya-Feldstein, Julie; Scaglioni, Pier Paolo (2013). RHOA-FAK Is a Required Signaling Axis for the Maintenance of KRAS-Driven Lung Adenocarcinomas. Cancer discovery, 3(4), pp. 444-457. American Association for Cancer Research 10.1158/2159-8290.CD-12-0388
Kaufmann, Thomas; Strasser, Andreas; Jost, Philipp J (2012). Fas death receptor signalling: roles of Bid and XIAP. Cell death and differentiation, 19(1), pp. 42-50. Basingstoke: Nature Publishing Group 10.1038/cdd.2011.121
North, Simon J; von Gunten, Stephan; Antonopoulos, Aristotelis; Trollope, Alana; MacGlashan, Donald W; Jang-Lee, Jihye; Dell, Anne; Metcalfe, Dean D; Kirshenbaum, Arnold S; Bochner, Bruce S; Haslam, Stuart M (2012). Glycomic analysis of human mast cells, eosinophils and basophils. Glycobiology, 22(1), pp. 12-22. Oxford: Oxford University Press 10.1093/glycob/cwr089
Braun, Marion; Jandus, Camilla; Maurer, Patrik; Hammann-Haenni, Anya; Schwarz, Katrin; Bachmann, Martin F; Speiser, Daniel E; Romero, Pedro (2012). Virus-like particles induce robust human T-helper cell responses. European journal of immunology, 42(2), pp. 330-40. Weinheim: Wiley-VCH 10.1002/eji.201142064
Baumgaertner, Petra; Jandus, Camilla; Rivals, Jean-Paul; Derré, Laurent; Lövgren, Tanja; Baitsch, Lukas; Guillaume, Philippe; Luescher, Immanuel F; Berthod, Gregoire; Matter, Maurice; Rufer, Nathalie; Michielin, Olivier; Speiser, Daniel E (2012). Vaccination-induced functional competence of circulating human tumor-specific CD8 T-cells. International journal of cancer, 130(11), pp. 2607-17. Malden, Mass.: Wiley-Blackwell 10.1002/ijc.26297
Salemi, Souzan; Yousefi, Shida; Constantinescu, Mihai A; Fey, Martin F; Simon, Hans-Uwe (2012). Autophagy is required for self-renewal and differentiation of adult human stem cells. Cell research, 22(2), pp. 432-5. London: Nature Publishing Group 10.1038/cr.2011.200
Galluzzi, L; Vitale, I; Abrams, J M; Alnemri, E S; Baehrecke, E H; Blagosklonny, M V; Dawson, T M; Dawson, V L; El-Deiry, W S; Fulda, S; Gottlieb, E; Green, D R; Hengartner, M O; Kepp, O; Knight, R A; Kumar, S; Lipton, S A; Lu, X; Madeo, F; Malorni, W; ... (2012). Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012. Cell death and differentiation, 19(1), pp. 107-20. Basingstoke: Nature Publishing Group 10.1038/cdd.2011.96
Badmann, Anastasia; Langsch, Stephanie; Keogh, Adrian; Brunner, Thomas; Kaufmann, Thomas; Corazza, Nadia (2012). TRAIL enhances paracetamol-induced liver sinusoidal endothelial cell death in a Bim- and Bid-dependent manner. Cell death & disease, 3(12), e447. London: Nature Publishing Group 10.1038/cddis.2012.185
Corazza, Nadia; Kaufmann, Thomas (2012). Novel insights into mechanisms of food allergy and allergic airway inflammation using experimental mouse models. Allergy, 67(12), pp. 1483-90. Oxford: Wiley-Blackwell 10.1111/all.12065
Huwiler, Andrea; Feuerherm, Astrid J; Sakem, Benjamin; Pastukhov, Oleksandr; Filipenko, Iuliia; Nguyen, Thuy; Johansen, Berit (2012). The ω3-polyunsaturated fatty acid derivatives AVX001 and AVX002 directly inhibit cytosolic phospholipase A(2) and suppress PGE(2) formation in mesangial cells. British journal of pharmacology, 167(8), pp. 1691-701. Oxford: Wiley-Blackwell 10.1111/j.1476-5381.2012.02114.x
Kotelevets, Nataliya; Fabbro, Doriano; Huwiler, Andrea; Zangemeister-Wittke, Uwe (2012). Targeting sphingosine kinase 1 in carcinoma cells decreases proliferation and survival by compromising PKC activity and cytokinesis. PLoS ONE, 7(6), e39209. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0039209
Koch, A; Völzke, A; Wünsche, C; Meyer zu Heringdorf, D; Huwiler, A; Pfeilschifter, J (2012). Thiazolidinedione-dependent activation of sphingosine kinase 1 causes an anti-fibrotic effect in renal mesangial cells. British journal of pharmacology, 166(3), pp. 1018-32. Oxford: Wiley-Blackwell 10.1111/j.1476-5381.2012.01824.x
Damgaard, Rune Busk; Nachbur, Ueli; Yabal, Monica; Wong, Wendy Wei-Lynn; Fiil, Berthe Katrine; Kastirr, Mischa; Rieser, Eva; Rickard, James Arthur; Bankovacki, Aleksandra; Peschel, Christian; Ruland, Juergen; Bekker-Jensen, Simon; Mailand, Niels; Kaufmann, Thomas; Strasser, Andreas; Walczak, Henning; Silke, John; Jost, Philipp J; Gyrd-Hansen, Mads (2012). The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in inflammation and innate immunity. Molecular cell, 46(6), pp. 746-58. Cambridge, Mass.: Cell Press 10.1016/j.molce1.2012.04.014
Ke, Francine; Voss, Anne; Kerr, Jeffrey; O'Reilly, Lorraine; Tai, Lin; Echeverry, Nohemy; Bouillet, Philippe; Strasser, Andreas; Kaufmann, Thomas (2012). BCL-2 family member BOK is widely expressed but its loss has only minimal impact in mice. Cell death and differentiation, 19(6), pp. 915-25. Basingstoke: Nature Publishing Group 10.1038/cdd.2011.210
von Gunten, Stephan; Kaufmann, Thomas (2012). Glucocorticoids 'on air'. Allergy, 67(2), pp. 144-6. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2011.02778.x
von Gunten, S; Marsland, B J; von Garnier, C; Simon, D (2012). Update in clinical allergy and immunology. Allergy, 67(12), pp. 1491-500. Oxford: Wiley-Blackwell 10.1111/all.12067
von Gunten, Stephan; Simon, Hans-Uwe (2012). Granulocyte death regulation by naturally occurring autoantibodies. Advances in experimental medicine and biology, 750, pp. 157-172. Wien: Springer
Stoeckle, Christina; Quecke, Paula; Rückrich, Thomas; Burster, Timo; Reich, Michael; Weber, Ekkehard; Kalbacher, Hubert; Driessen, Christoph; Melms, Arthur; Tolosa, Eva (2012). Cathepsin S dominates autoantigen processing in human thymic dendritic cells. Journal of autoimmunity, 38(4), pp. 332-43. Amsterdam: Elsevier 10.1016/j.jaut.2012.02.003
Krudewig, J; Baumann, U; Bernuth von, H; Borte, M; Burkhard-Meier, U; Dueckers, G; Foerster-Waldl, E; Franke, K; Habermehl, P; Hönig, M; Kern, W; Kösters, K; Kugel, K; Lehrnbecher, T; Liese, J; Marks, R; Müller, G A; Müller, R; Nadal, D; Peter, H-H; ... (2012). [Interdisciplinary AWMF guideline for the treatment of primary antibody deficiencies]. Klinische Pädiatrie, 224(6), pp. 404-15. Stuttgart: Thieme 10.1055/s-0032-1323837
Charignon, Delphine; Späth, Peter; Martin, Ludovic; Drouet, Christian (2012). Icatibant , the bradykinin B2 receptor antagonist with target to the interconnected kinin systems. Expert opinion on pharmacotherapy, 13(15), pp. 2233-47. London: Informa Healthcare 10.1517/14656566.2012.723692
Späth, Peter J; Lutz, Hans U (2012). Naturally occurring antibodies/autoantibodies in polyclonal immunoglobulin concentrates. Advances in experimental medicine and biology, 750, pp. 239-261. Wien: Springer
Wahn, V; Aberer, W; Eberl, W; Faßhauer, M; Kühne, T; Kurnik, K; Magerl, M; Meyer-Olson, D; Martinez-Saguer, I; Späth, P; Staubach-Renz, P; Kreuz, W (2012). Hereditary angioedema (HAE) in children and adolescents--a consensus on therapeutic strategies. European journal of pediatrics, 171(9), pp. 1339-48. Berlin: Springer 10.1007/s00431-012-1726-4
Heine, Markus; Freund, Barbara; Nielsen, Peter; Jung, Caroline; Reimer, Rudolph; Hohenberg, Heinrich; Zangemeister-Wittke, Uwe; Wester, Hans-Juergen; Lüers, Georg H; Schumacher, Udo (2012). High interstitial fluid pressure is associated with low tumour penetration of diagnostic monoclonal antibodies applied for molecular imaging purposes. PLoS ONE, 7(5), e36258. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0036258
Simon, Manuel; Zangemeister-Wittke, Uwe; Plückthun, Andreas (2012). Facile double-functionalization of designed ankyrin repeat proteins using click and thiol chemistries. Bioconjugate chemistry, 23(2), pp. 279-86. Washington, D.C.: American Chemical Society 10.1021/bc200591x
Valent, Peter; Klion, Amy D; Rosenwasser, Lanny J; Arock, Michel; Bochner, Bruce S; Butterfield, Joseph H; Gotlib, Jason; Haferlach, Torsten; Hellmann, Andrzej; Horny, Hans-Peter; Leiferman, Kristin M; Metzgeroth, Georgia; Matsumoto, Kenji; Reiter, Andreas; Roufosse, Florence; Rothenberg, Marc E; Simon, Hans-Uwe; Sotlar, Karl; Vandenberghe, Peter; Weller, Peter F; ... (2012). ICON: Eosinophil Disorders. World Allergy Organization journal, 5(12), pp. 174-181. Hagerstown, Md.: Wolters Kluwer Health Lippincott Williams & Wilkins
Yousefi, Shida; Simon, Dagmar; Simon, Hans-Uwe (2012). Eosinophil extracellular DNA traps: molecular mechanisms and potential roles in disease. Current opinion in immunology, 24(6), pp. 736-9. Kidlington, UK: Elsevier 10.1016/j.coi.2012.08.010
Bochner, Bruce S; Book, Wendy; Busse, William W; Butterfield, Joseph; Furuta, Glenn T; Gleich, Gerald J; Klion, Amy D; Lee, James J; Leiferman, Kristin M; Minnicozzi, Michael; Moqbel, Redwan; Rothenberg, Marc E; Schwartz, Lawrence B; Simon, Hans-Uwe; Wechsler, Michael E; Weller, Peter F (2012). Workshop report from the National Institutes of Health Taskforce on the Research Needs of Eosinophil-Associated Diseases (TREAD). Journal of allergy and clinical immunology, 130(3), pp. 587-96. St. Louis, Mo.: Mosby 10.1016/j.jaci.2012.07.024
Wechsler, Michael E; Fulkerson, Patricia C; Bochner, Bruce S; Gauvreau, Gail M; Gleich, Gerald J; Henkel, Tim; Kolbeck, Roland; Mathur, Sameer K; Ortega, Hector; Patel, Jatin; Prussin, Calman; Renzi, Paolo; Rothenberg, Marc E; Roufosse, Florence; Simon, Dagmar; Simon, Hans-Uwe; Wardlaw, Andrew; Weller, Peter F; Klion, Amy D (2012). Novel targeted therapies for eosinophilic disorders. Journal of allergy and clinical immunology, 130(3), pp. 563-71. St. Louis, Mo.: Mosby 10.1016/j.jaci.2012.07.027
Morshed, M; Yousefi, S; Stöckle, C; Simon, H-U; Simon, D (2012). Thymic stromal lymphopoietin stimulates the formation of eosinophil extracellular traps. Allergy, 67(9), pp. 1127-37. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2012.02868.x
Conus, Sébastien; Pop, Cristina; Snipas, Scott J; Salvesen, Guy S; Simon, Hans-Uwe (2012). Cathepsin D primes caspase-8 activation by multiple intra-chain proteolysis. Journal of biological chemistry, 287(25), pp. 21142-51. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M111.306399
Valent, Peter; Klion, Amy D; Horny, Hans-Peter; Roufosse, Florence; Gotlib, Jason; Weller, Peter F; Hellmann, Andrzej; Metzgeroth, Georgia; Leiferman, Kristin M; Arock, Michel; Butterfield, Joseph H; Sperr, Wolfgang R; Sotlar, Karl; Vandenberghe, Peter; Haferlach, Torsten; Simon, Hans-Uwe; Reiter, Andreas; Gleich, Gerald J (2012). Contemporary consensus proposal on criteria and classification of eosinophilic disorders and related syndromes. Journal of allergy and clinical immunology, 130(3), 607-612.e9. St. Louis, Mo.: Mosby 10.1016/j.jaci.2012.02.019
Simon, Hans-Uwe; Klion, Amy (2012). Therapeutic approaches to patients with hypereosinophilic syndromes. Seminars in hematology, 49(2), pp. 160-70. Philadelphia, Pa.: W.B. Saunders 10.1053/j.seminhematol.2012.01.002
Simon, Dagmar; Simon, Hans-Uwe (2012). New drug targets in atopic dermatitis. Chemical immunology and allergy, 96, pp. 126-131. Basel: Karger
Simon, Hans-Uwe (2012). Autophagy in myocardial differentiation and cardiac development. Circulation research, 110(4), pp. 524-5. Baltimore, Md.: Lippincott Williams & Wilkins 10.1161/CIRCRESAHA.112.265157
Straumann, A; Aceves, S S; Blanchard, C; Collins, M H; Furuta, G T; Hirano, I; Schoepfer, A M; Simon, D; Simon, H-U (2012). Pediatric and adult eosinophilic esophagitis: similarities and differences. Allergy, 67(4), pp. 477-90. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2012.02787.x
Kerstan, A; Simon, H-U; Yousefi, S; Leverkus, M (2012). Extensive accumulation of eosinophil extracellular traps in bullous delayed-pressure urticaria: a pathophysiological link? British journal of dermatology, 166(5), pp. 1151-2. Oxford: Wiley-Blackwell 10.1111/j.1365-2133.2012.10848.x
Mihalache, Cristina C; Simon, Hans-Uwe (2012). Autophagy regulation in macrophages and neutrophils. Experimental cell research, 318(11), pp. 1187-92. San Diego, Calif.: Elsevier 10.1016/j.yexcr.2011.12.021
Simon, HU; Yousefi, S (2012). Mitochondrial DNA released by eosinophils contributes to innate immunity. Pisa: Pacini Editore S.p.A.
Simon, HU; Simon, D (2012). Biologics targeting T and B cells improve atopic eczema. Pisa: Pacini Editore S.p.A.
Lammel, Verena; Stoeckle, Christina; Padberg, Barbara; Zweifel, Roland; Kienle, Dirk L; Reinhart, Walter H; Simon, Hans-Uwe (2012). Hypereosinophilia driven by GM-CSF in large-cell carcinoma of the lung. Lung cancer, 76(3), pp. 493-5. Amsterdam: Elsevier 10.1016/j.lungcan.2012.02.014
Simon, HU; Ziegler, S.F. (2012). Allergic responses in the lung and skin: new players in the game. Immunology and allergy clinics of North America, 24(6), pp. 698-699. Philadelphia, Pa.: Elsevier 10.1016/j.coi.2012.10.006
Valent, Peter; Gleich, Gerald J; Reiter, Andreas; Roufosse, Florence; Weller, Peter F; Hellmann, Andrzej; Metzgeroth, Georgia; Leiferman, Kristin M; Arock, Michel; Sotlar, Karl; Butterfield, Joseph H; Cerny-Reiterer, Sabine; Mayerhofer, Matthias; Vandenberghe, Peter; Haferlach, Torsten; Bochner, Bruce S; Gotlib, Jason; Horny, Hans-Peter; Simon, Hans-Uwe and Klion, Amy D (2012). Pathogenesis and classification of eosinophil disorders: a review of recent developments in the field. Expert review of hematology, 5(2), pp. 157-76. London: Expert Reviews 10.1586/EHM.11.81
Zangemeister-Wittke, Uwe; Simon, Hans-Uwe (2012). Myelosuppression. In: Schwab, Manfred (ed.) Encyclopedia of Cancer (pp. 2437-2440). Heidelberg: Springer-Verlage 10.1007/978-3-642-16483-5
Rabellino, A.; Carter, B.; Konstantinidou, Georgia; Wu, S.-Y.; Rimessi, A.; Byers, L. A.; Heymach, J. V.; Girard, L.; Chiang, C.-M.; Teruya-Feldstein, J.; Scaglioni, P. P. (2012). The SUMO E3-ligase PIAS1 Regulates the Tumor Suppressor PML and Its Oncogenic Counterpart PML-RARA. Cancer research, 72(9), pp. 2275-2284. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-11-3159
Scaglioni, Pier Paolo; Rabellino, Andrea; Yung, Thomas M.; Bernardi, Rosa; Choi, Sooyeon; Konstantinidou, Georgia; Nardella, Caterina; Cheng, Ke; Pandolfi, Pier Paolo (2012). Translation-dependent mechanisms lead to PML upregulation and mediate oncogenic K-RAS-induced cellular senescence. EMBO molecular medicine, 4(7), pp. 594-602. EMBO Press 10.1002/emmm.201200233
Bisaro, Brigitte; Montani, Maura; Konstantinidou, Georgia; Marchini, Cristina; Pietrella, Lucia; Iezzi, Manuela; Galiè, Mirco; Orso, Francesca; Camporeale, Annalisa; Colombo, Shana M; Di Stefano, Paola; Tornillo, Giusy; Camacho-Leal, Maria P; Turco, Emilia; Taverna, Daniela; Cabodi, Sara; Amici, Augusto; Defilippi, Paola (2012). p130Cas/Cyclooxygenase-2 axis in the control of mesenchymal plasticity of breast cancer cells. Breast cancer research, 14(5), R137. BioMed Central Ltd. 10.1186/bcr3342
Badmann, A.; Keough, A.; Kaufmann, T.; Bouillet, P.; Brunner, T.; Corazza, N. (2011). Role of TRAIL and the pro-apoptotic Bcl-2 homolog Bim in acetaminophen-induced liver damage. Cell death & disease, 2(6), e171. London: Nature Publishing Group 10.1038/cddis.2011.55
Sury, Matthias D.; Vorlet-Fawer, Lorianne; Agarinis, Claudia; Yousefi, Shida; Grandgirard, Denis; Leib, Stephen L.; Christen, Stephan (2011). Restoration of Akt activity by the bisperoxovanadium compound bpV(pic) attenuates hippocampal apoptosis in experimental neonatal pneumococcal meningitis. Neurobiology of disease, 41(1), pp. 201-208. Amsterdam: Elsevier 10.1016/j.nbd.2010.09.007
Ter Braak, Michael; Claas, Ralf Frederik; Hegen, Bianca; Labocha, Sandra; Ferreirós, Nerea; Pfeilschifter, Josef; Huwiler, Andrea; van Echten-Deckert, Gerhild; Meyer Zu Heringdorf, Dagmar (2011). Cis-4-methylsphingosine is a sphingosine-1-phosphate receptor modulator. Biochemical pharmacology, 81(5), pp. 617-25. New York, N.Y.: Elsevier 10.1016/j.bcp.2010.12.002
Patricia, Martin-Killias; Stefan, Nikolas; Rothschild, Sacha; Plückthun, Andreas; Zangemeister-Wittke, Uwe (2011). A novel fusion toxin derived from an EpCAM-specific designed ankyrin repeat protein has potent antitumor activity. Clinical cancer research, 17(1), pp. 100-10. Philadelphia, Pa.: American Association for Cancer Research 10.1158/1078-0432.CCR-10-1303
Yuki, N; Watanabe, H; Nakajima, T; Späth, P J (2011). IVIG blocks complement deposition mediated by anti-GM1 antibodies in multifocal motor neuropathy. Journal of neurology, neurosurgery and psychiatry, 82(1), pp. 87-91. London: BMJ Publishing Group 10.1136/jnnp.2010.205856
Schaub, A; von Gunten, S; Vogel, M; Wymann, S; Rüegsegger, M; Stadler, B M; Spycher, M; Simon, H-U; Miescher, S (2011). Dimeric IVIG contains natural anti-Siglec-9 autoantibodies and their anti-idiotypes. Allergy, 66(8), pp. 1030-7. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2011.02579.x
Pfeilschifter, Waltraud; Czech-Zechmeister, Bo?ena; Sujak, Marian; Mirceska, Ana; Koch, Alexander; Rami, Abdelhaq; Steinmetz, Helmuth; Foerch, Christian; Huwiler, Andrea; Pfeilschifter, Josef (2011). Activation of sphingosine kinase 2 is an endogenous protective mechanism in cerebral ischemia. Biochemical and biophysical research communications, 413(2), pp. 212-7. Orlando, Fla.: Academic Press 10.1016/j.bbrc.2011.08.070
Huwiler, Andrea; Bourquin, Florence; Kotelevets, Nataliya; Pastukhov, Oleksandr; Capitani, Guido; Grütter, Markus G; Zangemeister-Wittke, Uwe (2011). A prokaryotic S1P lyase degrades extracellular S1P in vitro and in vivo: implication for treating hyperproliferative disorders. PLoS ONE, 6(8), e22436. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0022436
Schröder, Matthias; Richter, Cornelia; Juan, Martina Herrero San; Maltusch, Katrin; Giegold, Oliver; Quintini, Gianluca; Pfeilschifter, Josef M; Huwiler, Andrea; Radeke, Heinfried H (2011). The sphingosine kinase 1 and S1P1 axis specifically counteracts LPS-induced IL-12p70 production in immune cells of the spleen. Molecular immunology, 48(9-10), pp. 1139-48. Amsterdam: Elsevier 10.1016/j.molimm.2011.02.007
Huwiler, Andrea; Kotelevets, Nataliya; Xin, Cuiyan; Pastukhov, Oleksandr; Pfeilschifter, Josef; Zangemeister-Wittke, Uwe (2011). Loss of sphingosine kinase-1 in carcinoma cells increases formation of reactive oxygen species and sensitivity to doxorubicin-induced DNA damage. British journal of pharmacology, 162(2), pp. 532-43. Oxford: Wiley-Blackwell 10.1111/j.1476-5381.2010.01053.x
Geering, Barbara; Gurzeler, Ursina; Federzoni, Elena; Kaufmann, Thomas; Simon, Hans-Uwe (2011). A novel TNFR1-triggered apoptosis pathway mediated by class IA PI3Ks in neutrophils. Blood, 117(22), pp. 5953-5962. Washington, D.C.: American Society of Hematology 10.1182/blood-2010-11-322206
Casulli, Sarah; Topçu, Selma; Fattoum, Lakhdar; von Gunten, Stephan; Simon, Hans-Uwe; Teillaud, Jean-Luc; Bayry, Jagadeesh; Kaveri, Srini V.; Elbim, Carole (2011). A differential concentration-dependent effect of IVIg on neutrophil functions: relevance for anti-microbial and anti-inflammatory mechanisms. PLoS ONE, 6(10), e26469. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0026469
Grader-Beck, Thomas; Boin, Francesco; von Gunten, Stephan; Smith, David; Rosen, Antony; Bochner, Bruce S (2011). Antibodies recognising sulfated carbohydrates are prevalent in systemic sclerosis and associated with pulmonary vascular disease. Annals of the rheumatic diseases, 70(12), pp. 2218-24. London: BMJ Publishing Group 10.1136/ard.2011.153130
Jandus, Camilla; Simon, Hans-Uwe; von Gunten, Stephan (2011). Targeting siglecs--a novel pharmacological strategy for immuno- and glycotherapy. Biochemical pharmacology, 82(4), pp. 323-32. New York, N.Y.: Elsevier 10.1016/j.bcp.2011.05.018
Stefan, Nikolas; Martin-Killias, Patricia; Wyss-Stoeckle, Sascha; Honegger, Annemarie; Zangemeister-Wittke, Uwe; Plückthun, Andreas (2011). DARPins recognizing the tumor-associated antigen EpCAM selected by phage and ribosome display and engineered for multivalency. Journal of molecular biology, 413(4), pp. 826-43. Amsterdam: Elsevier 10.1016/j.jmb.2011.09.016
Lange, Annika; Gustke, Heike; Glassmeier, Günter; Heine, Markus; Zangemeister-Wittke, Uwe; Schwarz, Jürgen R; Schumacher, Udo; Lange, Tobias (2011). Neuronal differentiation by indomethacin and IBMX inhibits proliferation of small cell lung cancer cells in vitro. Lung cancer, 74(2), pp. 178-87. Amsterdam: Elsevier 10.1016/j.lungcan.2011.03.017
Späth, Peter J; Hunziker, Thomas (2011). Will immunoglobulin therapy of autoimmune blistering skin diseases survive the new financial management of inpatients? Dermatology, 222(2), pp. 138-9. Basel: Karger 10.1159/000323006
Hruz, Petr; Straumann, Alex; Bussmann, Christian; Heer, Pius; Simon, Hans-Uwe; Zwahlen, Marcel; Beglinger, Christoph; Schoepfer, Alain M (2011). Escalating incidence of eosinophilic esophagitis: a 20-year prospective, population-based study in Olten County, Switzerland. Journal of allergy and clinical immunology, 128(6), 1349-1350.e5. St. Louis, Mo.: Mosby 10.1016/j.jaci.2011.09.013
Geering Truffer, Barbara; Schmidt-Mende, Jan; Federzoni, Elena; Stoeckle, Christina; Simon, Hans-Uwe (2011). Protein overexpression following lentiviral infection of primary mature neutrophils is due to pseudotransduction. Journal of immunological methods, 373(1-2), pp. 209-18. Amsterdam: Elsevier 10.1016/j.jim.2011.08.024
Roth, N; Städler, S; Lemann, M; Hösli, S; Simon, H-U; Simon, D (2011). Distinct eosinophil cytokine expression patterns in skin diseases - the possible existence of functionally different eosinophil subpopulations. Allergy, 66(11), pp. 1477-86. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2011.02694.x
Geering, Barbara; Simon, Hans-Uwe (2011). A novel signaling pathway in TNF?-induced neutrophil apoptosis. Cell cycle, 10(17), pp. 2821-2. Georgetown, Tex.: Landes Bioscience 10.4161/cc.10.17.16747
Bousquet, Jean; Anto, Josep M; Sterk, Peter J; Adcock, Ian M; Chung, Kian Fan; Roca, Josep; Agusti, Alvar; Brightling, Chris; Cambon-Thomsen, Anne; Cesario, Alfredo; Abdelhak, Sonia; Antonarakis, Stylianos E; Avignon, Antoine; Ballabio, Andrea; Baraldi, Eugenio; Baranov, Alexander; Bieber, Thomas; Bockaert, Joël; Brahmachari, Samir; Brambilla, Christian; ... (2011). Systems medicine and integrated care to combat chronic noncommunicable diseases. Genome medicine, 3(7), p. 43. London: BioMed Central 10.1186/gm259
Geering, B; Simon, H-U (2011). Peculiarities of cell death mechanisms in neutrophils. Cell death and differentiation, 18(9), pp. 1457-69. Basingstoke: Nature Publishing Group 10.1038/cdd.2011.75
Bieber, T; Simon, H-U (2011). Allergen-specific immunotherapy: current concepts and future directions. Allergy, 66(6), pp. 709-12. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2011.02595.x
Mihalache, Cristina C; Yousefi, Shida; Conus, Sébastien; Villiger, Peter M; Schneider, E Marion; Simon, Hans-Uwe (2011). Inflammation-associated autophagy-related programmed necrotic death of human neutrophils characterized by organelle fusion events. Journal of immunology, 186(11), pp. 6532-42. Bethesda, Md.: American Association of Immunologists 10.4049/jimmunol.1004055
Stuck, M C; Straumann, A; Simon, H-U (2011). Relative lack of T regulatory cells in adult eosinophilic esophagitis - no normalization after corticosteroid therapy. Allergy, 66(5), pp. 705-7. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2010.02525.x
Dworski, Ryszard; Simon, Hans-Uwe; Hoskins, Aimee; Yousefi, Shida (2011). Eosinophil and neutrophil extracellular DNA traps in human allergic asthmatic airways. Journal of allergy and clinical immunology, 127(5), pp. 1260-6. St. Louis, Mo.: Mosby 10.1016/j.jaci.2010.12.1103
Straumann, Alex; Conus, Sebastien; Degen, Lukas; Frei, Cornelia; Bussmann, Christian; Beglinger, Christoph; Schoepfer, Alain; Simon, Hans-Uwe (2011). Long-term budesonide maintenance treatment is partially effective for patients with eosinophilic esophagitis. Clinical gastroenterology and hepatology, 9(5), 400-9.e1. Philadelphia, Pa.: Elsevier 10.1016/j.cgh.2011.01.017
Simon, Dagmar; Hoesli, Susanne; Roth, Nina; Staedler, Simon; Yousefi, Shida; Simon, Hans-Uwe (2011). Eosinophil extracellular DNA traps in skin diseases. Journal of allergy and clinical immunology, 127(1), pp. 194-9. St. Louis, Mo.: Mosby 10.1016/j.jaci.2010.11.002
Delforge, M; Farber, C M; Spath, P; Kaveri, S; Witte, T; Misbah, S A; Hübner, R; Haerynck, F; Latinne, D; Muylle, L; Toungouz, M; Deneys, V; Superior Health Council Belgium, (2011). Recommended indications for the administration of polyclonal immunoglobulin preparations. Acta clinica belgica, 66(5), pp. 346-60. Brussels: Acta clinica belgica 10.2143/ACB.66.5.2062586
Späth, P. J. (2011). Highlights from the 7th C1 Inhibitor Deficiency Workshop, Budapest, Hungary.
Simon, H.U. (2011). Old and new allergic diseases: From diagnosis to drug therapy. European journal of pharmaceutical sciences, p. 7. Amsterdam: Elsevier
Kroemer, G; Martinon, F; Lippens, S; Green, D.R.; Knight, R; Vandenabeele, G; Piacentini, M; Nagata, S; Borner, C; Simon, H.U.; Kramer, P; Melino, G (2011). Jürg Tschopp - 1951 2011 - an immortal contribution. Cell death and differentiation, 18(7), pp. 1087-1088. Basingstoke: Nature Publishing Group 10.1038/cdd.2011.46
Abbas, M; Lalive, PH; Chofflon, M; Simon, HU; Chizzolini, C; Ribi, C (2011). Hypereosinophilia in patients with mutiple sclerosis treated with natalizumab. Neurology, 77(16), pp. 1561-1564. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1212/WNL.0b013e318233b391
Eloranta, Jyrki J; Wenger, Christa; Mwinyi, Jessica; Hiller, Christian; Gubler, Christoph; Vavricka, Stephan R; Fried, Michael; Kullak-Ublick, Gerd A; Swiss IBD Cohort Study Group, The (2011). Association of a common vitamin D-binding protein polymorphism with inflammatory bowel disease. Pharmacogenetics and genomics, 21(9), pp. 559-64. London: Lippincott Williams & Wilkins 10.1097/FPC.0b013e328348f70c
El-Hashim, Ahmed; Yousefi, Shida; Edafiogho, Ivan; Raghupathy, Raj; Yousif, Mariam; Simon, Hans-Uwe (2010). Anti-inflammatory and immunosuppressive effects of the enaminone E121. European journal of pharmacology, 632(1-3), pp. 73-78. Amsterdam: Elsevier 10.1016/j.ejphar.2009.12.004
Schoepfer, Alain M; Gonsalves, Nirmala; Bussmann, Christian; Conus, Sébastien; Simon, Hans-Uwe; Straumann, Alex; Hirano, Ikuo (2010). Esophageal Dilation in Eosinophilic Esophagitis: Effectiveness, Safety, and Impact on the Underlying Inflammation. American journal of gastroenterology, 105(5), pp. 1062-1070. New York, N.Y.: Nature 10.1038/ajg.2009.657
Britschgi, Adrian; Simon, Hans-Uwe; Tobler, Andreas; Fey, Martin F; Tschan, Mario P (2010). Epigallocatechin-3-gallate induces cell death in acute myeloid leukaemia cells and supports all-trans retinoic acid-induced neutrophil differentiation via death-associated protein kinase 2. British journal of haematology, 149(1), pp. 55-64. Oxford: Wiley-Blackwell 10.1111/j.1365-2141.2009.08040.x
Schwalm, Stephanie; Pfeilschifter, Josef; Huwiler, Andrea (2010). Sphingosine kinase 1 is critically involved in nitric oxide-mediated human endothelial cell migration and tube formation. British journal of pharmacology, 160(7), pp. 1641-51. Oxford: Wiley-Blackwell 10.1111/j.1476-5381.2010.00818.x
Puneet, Padmam; Yap, Celestial T; Wong, Lingkai; Lam, Yulin; Koh, Dow Rhoon; Moochhala, Shabbir; Pfeilschifter, Josef; Huwiler, Andrea; Melendez, Alirio J (2010). SphK1 regulates proinflammatory responses associated with endotoxin and polymicrobial sepsis. Science, 328(5983), pp. 1290-4. Washington, D.C.: American Association for the Advancement of Science 10.1126/science.1188635
Ren, Shuyu; Xin, Cuiyan; Pfeilschifter, Josef; Huwiler, Andrea (2010). A novel mode of action of the putative sphingosine kinase inhibitor 2-(p-hydroxyanilino)-4-(p-chlorophenyl) thiazole (SKI II): induction of lysosomal sphingosine kinase 1 degradation. Cellular physiology and biochemistry, 26(1), pp. 97-104. Basel: Karger 10.1159/000315110
Förster, Ankathrin; Emmler, Tanja; Schwalm, Stephanie; Ebadi, Mahsa; Heringdorf, Dagmar Meyer Zu; Nieuwenhuis, Barbara; Kleuser, Burkhardt; Huwiler, Andrea; Pfeilschifter, Josef (2010). Glucocorticoids protect renal mesangial cells from apoptosis by increasing cellular sphingosine-1-phosphate. Kidney international, 77(10), pp. 870-9. New York, N.Y.: Nature Publishing Group 10.1038/ki.2010.62
Jost, Philipp J; Kaufmann, Thomas (2010). Cancer caused by too much apoptosis--an intriguing contradiction? Hepatology, 51(4), pp. 1110-1112. Hoboken, N.J.: Wiley Interscience 10.1002/hep.23314
von Gunten, Stephan; Simon, Hans-Uwe (2010). Cell death modulation by intravenous immunoglobulin. Journal of clinical immunology, 30 Suppl 1, S24-30. New York, N.Y.: Springer US; http://www.springer-ny.com 10.1007/s10875-010-9411-8
Derré, Laurent; Jandus, Camilla; Baumgaertner, Petra; Posevitz, Vilmos; Devêvre, Estelle; Romero, Pedro; Speiser, Daniel E (2010). Quantitative multiparameter assays to measure the effect of adjuvants on human antigen-specific CD8 T-cell responses. Methods in molecular biology, 626, pp. 231-249. Totowa, N.J.: Humana Press 10.1007/978-1-60761-585-9_16
Derré, Laurent; Rivals, Jean-Paul; Jandus, Camilla; Pastor, Sonia; Rimoldi, Donata; Romero, Pedro; Michielin, Olivier; Olive, Daniel; Speiser, Daniel E (2010). BTLA mediates inhibition of human tumor-specific CD8+ T cells that can be partially reversed by vaccination. Journal of clinical investigation, 120(1), pp. 157-67. Ann Arbor, Mich.: American Society for Clinical Investigation 10.1172/JCI40070
Sevenich, Lisa; Hagemann, Sascha; Stoeckle, Christina; Tolosa, Eva; Peters, Christoph; Reinheckel, Thomas (2010). Expression of human cathepsin L or human cathepsin V in mouse thymus mediates positive selection of T helper cells in cathepsin L knock-out mice. Biochimie, 92(11), pp. 1674-80. Paris: Elsevier Masson SAS 10.1016/j.biochi.2010.03.014
Lucas, Mary; Hugh-Jones, Ken; Welby, Angela; Misbah, Siraj; Spaeth, Peter; Chapel, Helen (2010). Immunomodulatory therapy to achieve maximum efficacy: doses, monitoring, compliance, and self-infusion at home. Journal of clinical immunology, 30 Suppl 1, S84-S89. New York, N.Y.: Springer 10.1007/s10875-010-9400-y
Schmidt-Mende, Jan; Geering, Barbara; Yousefi, Shida; Simon, Hans-Uwe (2010). Lysosomal degradation of RhoH protein upon antigen receptor activation in T but not B cells. European journal of immunology, 40(2), pp. 525-9. Weinheim: Wiley-VCH 10.1002/eji.200939556
Tschan, M P; Simon, H-U (2010). The role of autophagy in anticancer therapy: promises and uncertainties. Journal of internal medicine, 268(5), pp. 410-8. Oxford: Blackwell Scientific Publications 10.1111/j.1365-2796.2010.02266.x
Straumann, Alex; Conus, Sebastien; Degen, Lukas; Felder, Stephanie; Kummer, Mirjam; Engel, Hansjürg; Bussmann, Christian; Beglinger, Christoph; Schoepfer, Alain; Simon, Hans-Uwe (2010). Budesonide is effective in adolescent and adult patients with active eosinophilic esophagitis. Gastroenterology, 139(5), 1526-37, 1537.e1. Philadelphia, Pa.: Elsevier 10.1053/j.gastro.2010.07.048
Simon, Hans-Uwe; Rothenberg, Marc E; Bochner, Bruce S; Weller, Peter F; Wardlaw, Andrew J; Wechsler, Michael E; Rosenwasser, Lanny J; Roufosse, Florence; Gleich, Gerald J; Klion, Amy D (2010). Refining the definition of hypereosinophilic syndrome. Journal of allergy and clinical immunology, 126(1), pp. 45-9. St. Louis, Mo.: Mosby 10.1016/j.jaci.2010.03.042
Conus, Sébastien; Straumann, Alex; Bettler, Eva; Simon, Hans-Uwe (2010). Mepolizumab does not alter levels of eosinophils, T cells, and mast cells in the duodenal mucosa in eosinophilic esophagitis. Journal of allergy and clinical immunology, 126(1), pp. 175-7. St. Louis, Mo.: Mosby 10.1016/j.jaci.2010.04.029
Berent-Maoz, Beata; Salemi, Souzan; Mankuta, David; Simon, Hans-Uwe; Levi-Schaffer, Francesca (2010). Human mast cells express intracellular TRAIL. Cellular immunology, 262(2), pp. 80-3. San Diego, Calif.: Elsevier 10.1016/j.cellimm.2010.02.003
Bieber, T; Simon, H-U (2010). Shaping the future of Allergy. Allergy, 65(1), p. 1. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2009.02272.x
Straumann, A; Conus, S; Grzonka, P; Kita, H; Kephart, G; Bussmann, C; Beglinger, C; Smith, D A; Patel, J; Byrne, M; Simon, H-U (2010). Anti-interleukin-5 antibody treatment (mepolizumab) in active eosinophilic oesophagitis: a randomised, placebo-controlled, double-blind trial. Gut, 59(1), pp. 21-30. London: BMJ Publishing Group 10.1136/gut.2009.178558
Bantel, Heike; Simon, Hans-Uwe (2010). DeltaNp73beta is oncogenic in hepatocellular carcinoma by blocking apoptosis signaling via death receptors and mitochondria. Cell cycle, 9(14), pp. 2710-1. Georgetown, Tex.: Landes Bioscience 10.4161/cc.9.14.12592
Bowen, Tom; Cicardi, Marco; Farkas, Henriette; Bork, Konrad; Longhurst, Hilary J; Zuraw, Bruce; Aygoeren-Pürsün, Emel; Craig, Timothy; Binkley, Karen; Hebert, Jacques; Ritchie, Bruce; Bouillet, Laurence; Betschel, Stephen; Cogar, Della; Dean, John; Devaraj, Ramachand; Hamed, Azza; Kamra, Palinder; Keith, Paul K; Lacuesta, Gina; ... (2010). 2010 International consensus algorithm for the diagnosis, therapy and management of hereditary angioedema. Allergy, asthma & clinical immunology, 6(1), p. 24. Hamilton, Ont.: B.C. Decker Inc.
Seizer, Peter; Schiemann, Susanne; Merz, Tobias; Daub, Karin; Bigalke, Boris; Stellos, Konstantinos; Müller, Iris; Stöckle, Christina; Müller, Karin; Gawaz, Meinrad; May, Andreas E (2010). CD36 and macrophage scavenger receptor a modulate foam cell formation via inhibition of lipid-laden platelet phagocytosis. Seminars in thrombosis and hemostasis, 36(2), pp. 157-62. New York, N.Y.: Thieme Medical Publishers 10.1055/s-0030-1251499
Wais-Nöcker, B; Stiner, U; Farkas, H; Späth, P; Varga, L (2010). Klinische Facetten des hereditären Angioödems bei einem Schweizer Patientenkollektiv Praxis 99
Colombo, María Isabel; Simon, Hans-Uwe (2010). Autophagy: in: Cell Death. In: Melino, Gerry; Vaux, David (eds.) Encyclopedia of Life Sciences (pp. 175-188). Chichester: John Wiley & Sons Ltd. 10.1002/9780470015902.a0021581
Simon, D; Simon, H.-U. (2010). Eosinophils in autoimmune bullous diseases. In: , (ed.) Autoimmune diseases of the skin, 3rd edition. Heidelberg: Springer Verlag
Marchini, Cristina; Montani, Maura; Konstantinidou, Georgia; Orrù, Rita; Mannucci, Silvia; Ramadori, Giorgio; Gabrielli, Federico; Baruzzi, Anna; Berton, Giorgio; Merigo, Flavia; Fin, Stefania; Iezzi, Manuela; Bisaro, Brigitte; Sbarbati, Andrea; Zerani, Massimo; Galiè, Mirco; Amici, Augusto; Shioda, Toshi (2010). Mesenchymal/Stromal Gene Expression Signature Relates to Basal-Like Breast Cancers, Identifies Bone Metastasis and Predicts Resistance to Therapies. PLoS ONE, 5(11), e14131. Public Library of Science 10.1371/journal.pone.0014131
Zangemeister-Wittke, Uwe; Simon, Hans-Uwe (2009). Myelosuppression. In: Schwab, Manfred (ed.) Encyclopedia of Cancer, 2nd Edition (pp. 2008-2010). Heidelberg: Springer Verlag 10.1007/978-3-540-47648-1_3940
Kassahn, D; Nachbur, U; Conus, S; Micheau, O; Schneider, P; Simon, H-U; Brunner, T (2009). Distinct requirements for activation-induced cell surface expression of preformed Fas/CD95 ligand and cytolytic granule markers in T cells. Cell death and differentiation, 16(1), pp. 115-24. Basingstoke: Nature Publishing Group 10.1038/cdd.2008.133
Salemi, S; Yousefi, S; Simon, D; Schmid, I; Moretti, L; Scapozza, L; Simon, H-U (2009). A novel FIP1L1-PDGFRA mutant destabilizing the inactive conformation of the kinase domain in chronic eosinophilic leukemia/hypereosinophilic syndrome. Allergy, 64(6), pp. 913-8. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2009.01943.x
Ogbogu, Princess U; Bochner, Bruce S; Butterfield, Joseph H; Gleich, Gerald J; Huss-Marp, Johannes; Kahn, Jean Emmanuel; Leiferman, Kristin M; Nutman, Thomas B; Pfab, Florian; Ring, Johannes; Rothenberg, Marc E; Roufosse, Florence; Sajous, Marie-Helene; Sheikh, Javed; Simon, Dagmar; Simon, Hans-Uwe; Stein, Miguel L; Wardlaw, Andrew; Weller, Peter F and Klion, Amy D (2009). Hypereosinophilic syndrome: a multicenter, retrospective analysis of clinical characteristics and response to therapy. Journal of allergy and clinical immunology, 124(6), 1319-25.e3. St. Louis, Mo.: Mosby 10.1016/j.jaci.2009.09.022
Czech, Bozena; Pfeilschifter, Waltraud; Mazaheri-Omrani, Niloufar; Strobel, Marc André; Kahles, Timo; Neumann-Haefelin, Tobias; Rami, Abdelhaq; Huwiler, Andrea; Pfeilschifter, Josef (2009). The immunomodulatory sphingosine 1-phosphate analog FTY720 reduces lesion size and improves neurological outcome in a mouse model of cerebral ischemia. Biochemical and biophysical research communications, 389(2), pp. 251-6. Orlando, Fla.: Academic Press 10.1016/j.bbrc.2009.08.142
Ren, Shuyu; Babelova, Andrea; Moreth, Kristin; Xin, Cuiyan; Eberhardt, Wolfgang; Doller, Anke; Pavenstädt, Hermann; Schaefer, Liliana; Pfeilschifter, Josef; Huwiler, Andrea (2009). Transforming growth factor-beta2 upregulates sphingosine kinase-1 activity, which in turn attenuates the fibrotic response to TGF-beta2 by impeding CTGF expression. Kidney international, 76(8), pp. 857-67. New York, N.Y.: Nature Publishing Group 10.1038/ki.2009.297
Huwiler, Andrea; Pfeilschifter, Josef (2009). Lipids as targets for novel anti-inflammatory therapies. Pharmacology & therapeutics, 124(1), pp. 96-112. Amsterdam: Elsevier 10.1016/j.pharmthera.2009.06.008
Pushparaj, Peter N; Manikandan, Jayapal; Tay, Hwee Kee; H'ng, Shiau Chen; Kumar, Srinivasan D; Pfeilschifter, Josef; Huwiler, Andrea; Melendez, Alirio J (2009). Sphingosine kinase 1 is pivotal for Fc epsilon RI-mediated mast cell signaling and functional responses in vitro and in vivo. Journal of immunology, 183(1), pp. 221-7. Bethesda, Md.: American Association of Immunologists 10.4049/jimmunol.0803430
Nieuwenhuis, Barbara; Lüth, Anja; Chun, Jerold; Huwiler, Andrea; Pfeilschifter, Josef; Schäfer-Korting, Monika; Kleuser, Burkhard (2009). Involvement of the ABC-transporter ABCC1 and the sphingosine 1-phosphate receptor subtype S1P(3) in the cytoprotection of human fibroblasts by the glucocorticoid dexamethasone. International journal of molecular medicine, 87(6), pp. 645-57. Athens: Spandidos Publications 10.1007/s00109-009-0468-x
Huwiler, A; Pfeilschifter, J (2009). Lipid signalling - Ample opportunitites for novel drug targets. BioForum Europe, 10/200, pp. 22-23. Darmstadt: GIT-Verlag
Bianchi, K; Jost, P J; Kaufmann, T; Rutkowski, R (2009). International EMBO Workshop on 'Model Organisms in Cell Death Research', Obergurgl (Austria). Cell death and differentiation, 16(8), pp. 1180-3. Basingstoke: Nature Publishing Group 10.1038/cdd.2009.60
O'Reilly, Lorraine A; Kruse, Elizabeth A; Puthalakath, Hamsa; Kelly, Priscilla N; Kaufmann, Thomas; Huang, David C S; Strasser, Andreas (2009). MEK/ERK-mediated phosphorylation of Bim is required to ensure survival of T and B lymphocytes during mitogenic stimulation. Journal of immunology, 183(1), pp. 261-9. Bethesda, Md.: American Association of Immunologists 10.4049/jimmunol.0803853
Jabbour, A M; Heraud, J E; Daunt, C P; Kaufmann, T; Sandow, J; O'Reilly, L A; Callus, B A; Lopez, A; Strasser, A; Vaux, D L; Ekert, P G (2009). Puma indirectly activates Bax to cause apoptosis in the absence of Bid or Bim. Cell death and differentiation, 16(4), pp. 555-63. Basingstoke: Nature Publishing Group 10.1038/cdd.2008.179
Winkler, Johannes; Martin-Killias, Patricia; Plückthun, Andreas; Zangemeister-Wittke, Uwe (2009). EpCAM-targeted delivery of nanocomplexed siRNA to tumor cells with designed ankyrin repeat proteins. Molecular cancer therapeutics, 8(9), pp. 2674-83. Philadelphia, Pa.: American Association for Cancer Research AACR 10.1158/1535-7163.MCT-09-0402
Sodeur, Stephan; Ullrich, Sebastian; Gustke, Heike; Zangemeister-Wittke, Uwe; Schumacher, Udo (2009). Increased numbers of spontaneous SCLC metastasis in absence of NK cells after subcutaneous inoculation of different SCLC cell lines into pfp/rag2 double knock out mice. Cancer letters, 282(2), pp. 146-51. Amsterdam: Elsevier 10.1016/j.canlet.2009.03.005
Mousavi-Shafaei, Parisa; Ziaee, Abed-Ali; Zangemeister-Wittke, Uwe (2009). Increased cytotoxicity of cisplatin in SK-MEL 28 melanoma cells upon down-regulation of melanoma inhibitor of apoptosis protein Iran Biomed J
Marinov, Marin; Ziogas, Algirdas; Pardo, Olivier E; Tan, Liwen Terence; Dhillon, Tony; Mauri, Francesco A; Lane, Heidi A; Lemoine, Nicholas R; Zangemeister-Wittke, Uwe; Seckl, Michael J; Arcaro, Alexandre (2009). AKT/mTOR pathway activation and BCL-2 family proteins modulate the sensitivity of human small cell lung cancer cells to RAD001. Clinical cancer research, 15(4), pp. 1277-87. Philadelphia, Pa.: American Association for Cancer Research 10.1158/1078-0432.CCR-08-2166
Kok, Klaartje; Geering, Barbara; Vanhaesebroeck, Bart (2009). Regulation of phosphoinositide 3-kinase expression in health and disease. Trends in biochemical sciences, 34(3), pp. 115-27. Cambridge: Elsevier Current Trends 10.1016/j.tibs.2009.01.003
von Gunten, Stephan; Smith, David F; Cummings, Richard D; Riedel, Stefan; Miescher, Sylvia; Schaub, Alexander; Hamilton, Robert G; Bochner, Bruce S (2009). Intravenous immunoglobulin contains a broad repertoire of anticarbohydrate antibodies that is not restricted to the IgG2 subclass. Journal of allergy and clinical immunology, 123(6), 1268-76.e15. St. Louis, Mo.: Mosby 10.1016/j.jaci.2009.03.013
von Gunten, Stephan; Bochner, Bruce S (2009). Expression and Function of Siglec-8 in Human Eosinophils, Basophils, and Mast Cells. In: Pawankar, Ruby; Holgate, Stephen T; Rosenwasser, Lanny J (eds.) Allergy Frontiers: Classification and Pathomechanisms. Allergy Frontiers: Vol. 2 (pp. 297-313). Japan: Springer 10.1007/978-4-431-88315-9_19
Luther, Claudia; Adamopoulou, Eleni; Stoeckle, Christina; Brucklacher-Waldert, Verena; Rosenkranz, Daniela; Stoltze, Lars; Lauer, Sigrid; Poeschel, Simone; Melms, Arthur; Tolosa, Eva (2009). Prednisolone treatment induces tolerogenic dendritic cells and a regulatory milieu in myasthenia gravis patients. Journal of immunology, 183(2), pp. 841-8. Bethesda, Md.: American Association of Immunologists 10.4049/jimmunol.0802046
Stoeckle, Christina; Gouttefangeas, Cécile; Hammer, Michael; Weber, Ekkehard; Melms, Arthur; Tolosa, Eva (2009). Cathepsin W expressed exclusively in CD8+ T cells and NK cells, is secreted during target cell killing but is not essential for cytotoxicity in human CTLs. Experimental hematology, 37(2), pp. 266-75. New York, N.Y.: Elsevier 10.1016/j.exphem.2008.10.011
Stoeckle, Christina; Sommandas, Vinod; Adamopoulou, Eleni; Belisle, Kurt; Schiekofer, Stephan; Melms, Arthur; Weber, Ekkehard; Driessen, Christoph; Boehm, Bernhard O; Tolosa, Eva; Burster, Timo (2009). Cathepsin G is differentially expressed in primary human antigen-presenting cells. Cellular immunology, 255(1-2), pp. 41-5. San Diego, Calif.: Elsevier 10.1016/j.cellimm.2008.10.001
Stoeckle, Christina; Tolosa, Eva (2009). Antigen Processing and Presentation in Multiple Sclerosis. Results and problems in cell differentiation, 51, pp. 149-172. Berlin: Springer
Stoeckle, Christina; Gleske, Anne-Kathrin (2009). Immunotherapy: from basic research to clinical applications. Cancer immunology, immunotherapy, 58(7), pp. 1129-36. Heidelberg: Springer 10.1007/s00262-008-0544-z
Bousquet, P J; Brozek, J; Bachert, C; Bieber, T; Bonini, S; Burney, P; Calderon, M; Canonica, G W; Compalati, E; Daures, J P; Delgado, L; Demoly, P; Dahl, R; Durham, S R; Kowalski, M L; Malling, H J; Merk, H; Papadopoulos, N; Passalacqua, G; Simon, H U; ... (2009). The CONSORT statement checklist in allergen-specific immunotherapy: a GA2LEN paper. Allergy, 64(12), pp. 1737-45. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2009.02232.x
Yousefi, S; Mihalache, C; Kozlowski, E; Schmid, I; Simon, H U (2009). Viable neutrophils release mitochondrial DNA to form neutrophil extracellular traps. Cell death and differentiation, 16(11), pp. 1438-44. Basingstoke: Nature Publishing Group 10.1038/cdd.2009.96
Daryadel, Arezoo; Yousefi, Shida; Troi, David; Schmid, Inès; Schmidt-Mende, Jan; Mordasini, Carlo; Dahinden, Clemens A; Ziemiecki, Andrew; Simon, Hans-Uwe (2009). RhoH/TTF negatively regulates leukotriene production in neutrophils. Journal of immunology, 182(10), pp. 6527-32. Bethesda, Md.: American Association of Immunologists 10.4049/jimmunol.0803846
Andina, N; Conus, S; Schneider, E M; Fey, M F; Simon, H U (2009). Induction of Bim limits cytokine-mediated prolonged survival of neutrophils. Cell death and differentiation, 16(9), pp. 1248-55. Basingstoke: Nature Publishing Group 10.1038/cdd.2009.50
Galluzzi, L; Aaronson, S A; Abrams, J; Alnemri, E S; Andrews, D W; Baehrecke, E H; Bazan, N G; Blagosklonny, M V; Blomgren, K; Borner, C; Bredesen, D E; Brenner, C; Castedo, M; Cidlowski, J A; Ciechanover, A; Cohen, G M; De Laurenzi, V; De Maria, R; Deshmukh, M; Dynlacht, B D; ... (2009). Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes. Cell death and differentiation, 16(8), pp. 1093-107. Basingstoke: Nature Publishing Group 10.1038/cdd.2009.44
Eisenberg-Lerner, A; Bialik, S; Simon, H-U; Kimchi, A (2009). Life and death partners: apoptosis, autophagy and the cross-talk between them. Cell death and differentiation, 16(7), pp. 966-75. Basingstoke: Nature Publishing Group 10.1038/cdd.2009.33
von Gunten, Stephan; Jakob, Stephan M; Geering, Barbara; Takala, Jukka; Simon, Hans-Uwe (2009). Different patterns of Siglec-9-mediated neutrophil death responses in septic shock. Shock, 32(4), pp. 386-92. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/SHK.0b013e3181a1bc98
Yousefi, Shida; Simon, Hans-Uwe (2009). Autophagy in cells of the blood. Biochimica and biophysica acta - molecular and cell biology of lipids, 1793(9), pp. 1461-4. New York, N.Y.: Elsevier 10.1016/j.bbamcr.2008.12.023
Simon, Hans-Uwe; Malhotra, Bimal (2009). The pharmacokinetic profile of fesoterodine: similarities and differences to tolterodine. Swiss medical weekly, 139(9-10), pp. 146-51. Muttenz: EMH Schweizerischer Ärzteverlag
Yousefi, Shida; Simon, Hans-Uwe (2009). Autophagy in cancer and chemotherapy. Results and problems in cell differentiation, 49, pp. 183-190. Berlin: Springer
Simon, Hans-Uwe (2009). Cell death in allergic diseases. Apoptosis, 14(4), pp. 439-46. New York, N.Y.: Springer US; http://www.springer-ny.com 10.1007/s10495-008-0299-1
Aits, Sonja; Gustafsson, Lotta; Hallgren, Oskar; Brest, Patrick; Gustafsson, Mattias; Trulsson, Maria; Mossberg, Ann-Kristin; Simon, Hans-Uwe; Mograbi, Baharia; Svanborg, Catharina (2009). HAMLET (human alpha-lactalbumin made lethal to tumor cells) triggers autophagic tumor cell death. International journal of cancer, 124(5), pp. 1008-19. Malden, Mass.: Wiley-Blackwell 10.1002/ijc.24076
Conus, Sébastien; Straumann, Alex; Simon, Hans-Uwe (2009). Anti-IL-5 (mepolizumab) therapy does not alter IL-5 receptor alpha levels in patients with eosinophilic esophagitis. Journal of allergy and clinical immunology, 123(1), 269; author reply 269-70. St. Louis, Mo.: Mosby 10.1016/j.jaci.2008.09.031
Andina, N; Didichenko, S; Schmidt-Mende, J; A.Dahinden, C.; Simon, Hans-Uwe (2009). Pim-1 but not PI3K is essential in the anti-apoptotic signalling casdace initiated by IL-5 in eosinophils. Journal of allergy and clinical immunology, pp. 603-611. St. Louis, Mo.: Mosby
Simon, D; Kozlowski, E; U.Simon, H. (2009). NK-T cells in atopic dermatitis. Allergy, 59(6), pp. 561-570. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2004.00476.x
Simon, Hans-Uwe (2009). Regulation of cell survival. In: Adkinson, N. Franklin; Busse, William W; Bochner, Bruce S; Holgate, Stephen T; Simons, Estelle R; Lemanske, Robert F (eds.) Middleton's Allergy: Principles and Practice, 7th Edition (pp. 413-421). Mosby
Colombo, M.I.; Simon, H.U. (2009). Autophagy. In: Encyclopedia of Life Sciences (ELS). Chichester: J. Wiley & Sons
Fernandez-Cruz, E; Kaveri, S V; Peter, H-H; Durandy, A; Cantoni, N; Quinti, I; Sorensen, R; Bussel, J B; Danieli, M G; Winkelmann, A; Bayry, J; Käsermann, F; Späth, P; Helbert, M; Salama, A; van Schaik, I N; Yuki, N (2009). 6th International Immunoglobulin Symposium: poster presentations. Clinical and experimental immunology, 158 Suppl 1(Suppl 1), pp. 60-67. Oxford: Blackwell Scientific Publications 10.1111/j.1365-2249.2009.04028.x
Scherr, C; Simon, M; Spranger, J; Baumgartner, S (2009). Effects of potentised substances on growth rate of the water plant Lemna gibba L. Complementary therapies in medicine, 17(2), pp. 63-70. Exeter: Elsevier 10.1016/j.ctim.2008.10.004
Andina, Nicola; Didichenko, Svetlana; Schmidt-Mende, Jan; Dahinden, Clemens A; Simon, Hans-Uwe (2009). Proviral integration site for Moloney murine leukemia virus 1, but not phosphatidylinositol-3 kinase, is essential in the antiapoptotic signaling cascade initiated by IL-5 in eosinophils. Journal of allergy and clinical immunology, 123(3), pp. 603-611. St. Louis, Mo.: Mosby 10.1016/j.jaci.2008.12.004
Konstantinidou, Georgia; Bey, E. A.; Rabellino, A.; Schuster, K.; Maira, M. S.; Gazdar, A. F.; Amici, A.; Boothman, D. A.; Scaglioni, P. P. (2009). Dual Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Blockade Is an Effective Radiosensitizing Strategy for the Treatment of Non-Small Cell Lung Cancer Harboring K-RAS Mutations. Cancer research, 69(19), pp. 7644-7652. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-09-0823
Conus, Sébastien; Perozzo, Remo; Reinheckel, Thomas; Peters, Christoph; Scapozza, Leonardo; Yousefi, Shida; Simon, Hans-Uwe (2008). Caspase-8 is activated by cathepsin D initiating neutrophil apoptosis during the resolution of inflammation. Journal of experimental medicine, 205(3), pp. 685-698. New York, N.Y.: Rockefeller University Press 10.1084/jem.20072152
Belyanskaya, Larisa L; Ziogas, Algirdas; Hopkins-Donaldson, Sally; Kurtz, Stefanie; Simon, Hans-Uwe; Stahel, Rolf; Zangemeister-Wittke, Uwe (2008). TRAIL-induced survival and proliferation of SCLC cells is mediated by ERK and dependent on TRAIL-R2/DR5 expression in the absence of caspase-8. Lung cancer, 60(3), pp. 355-65. Amsterdam: Elsevier 10.1016/j.lungcan.2007.11.005
Simon, Dagmar; Salemi, Souzan; Yousefi, Shida; Simon, Hans-Uwe (2008). Primary resistance to imatinib in Fip1-like 1-platelet-derived growth factor receptor alpha-positive eosinophilic leukemia. Journal of allergy and clinical immunology, 121(4), pp. 1054-6. St. Louis, Mo.: Mosby 10.1016/j.jaci.2007.11.027
Federzoni, Elena; Gordon, Grace; Müller, Stefan; Schmid, Inès; Simon, Hans-Uwe; Yousefi, Shida (2008). Expression of CD95 on mature leukocytes of MRL/lpr mice after transplantation of genetically modified bone marrow stem cells. Immunology letters, 117(1), pp. 45-9. Amsterdam: Elsevier 10.1016/j.imlet.2007.11.019
Kostylina, G; Simon, D; Fey, M F; Yousefi, S; Simon, H U (2008). Neutrophil apoptosis mediated by nicotinic acid receptors (GPR109A). Cell death and differentiation, 15(1), pp. 134-42. Basingstoke: Nature Publishing Group 10.1038/sj.cdd.4402238
Kuhn, A; Leupin, N; Fey, M.F.; Yousefi, S; Simon, H.U. (2008). Leukaemia cell lines are robust in vitro models - response to MacLeod & Drexler. British journal of haematology(142), pp. 138-141. Oxford: Wiley-Blackwell
Hofmann, Lotte P; Ren, Shuyu; Schwalm, Stephanie; Pfeilschifter, Josef; Huwiler, Andrea (2008). Sphingosine kinase 1 and 2 regulate the capacity of mesangial cells to resist apoptotic stimuli in an opposing manner. Biological chemistry, 389(11), pp. 1399-407. Berlin: Walter de Gruyter 10.1515/BC.2008.160
Huwiler, Andrea; Pfeilschifter, Josef (2008). New players on the center stage: sphingosine 1-phosphate and its receptors as drug targets. Biochemical pharmacology, 75(10), pp. 1893-900. New York, N.Y.: Elsevier 10.1016/j.bcp.2007.12.018
Schwalm, Stephanie; Döll, Frauke; Römer, Isolde; Bubnova, Svetlana; Pfeilschifter, Josef; Huwiler, Andrea (2008). Sphingosine kinase-1 is a hypoxia-regulated gene that stimulates migration of human endothelial cells. Biochemical and biophysical research communications, 368(4), pp. 1020-5. Orlando, Fla.: Academic Press 10.1016/j.bbrc.2008.01.132
Schade-Kampmann, G; Huwiler, A; Hebeisen, M; Hessler, T; Di Berardino, M (2008). On-chip non-invasive and label-free cell discrimination by impedance spectroscopy. Anaesthesia, 41(5), pp. 830-40. Oxford: Wiley-Blackwell 10.1111/j.1365-2184.2008.00548.x
Doller, Anke; Akool, El-Sayed; Huwiler, Andrea; Müller, Roswitha; Radeke, Heinfried H; Pfeilschifter, Josef; Eberhardt, Wolfgang (2008). Posttranslational modification of the AU-rich element binding protein HuR by protein kinase Cdelta elicits angiotensin II-induced stabilization and nuclear export of cyclooxygenase 2 mRNA. Molecular and cellular biology, 28(8), pp. 2608-25. Washington, D.C.: American Society for Microbiology 10.1128/MCB.01530-07
Walter, Dorothée; Schmich, Kathrin; Vogel, Sandra; Pick, Robert; Kaufmann, Thomas; Hochmuth, Florian Christoph; Haber, Angelika; Neubert, Karin; McNelly, Sabine; von Weizsäcker, Fritz; Merfort, Irmgard; Maurer, Ulrich; Strasser, Andreas; Borner, Christoph (2008). Switch from type II to I Fas/CD95 death signaling on in vitro culturing of primary hepatocytes. Hepatology, 48(6), pp. 1942-53. Hoboken, N.J.: Wiley Interscience 10.1002/hep.22541
McKenzie, Mark D; Carrington, Emma M; Kaufmann, Thomas; Strasser, Andreas; Huang, David C S; Kay, Thomas W H; Allison, Janette; Thomas, Helen E (2008). Proapoptotic BH3-only protein Bid is essential for death receptor-induced apoptosis of pancreatic beta-cells. Diabetes, 57(5), pp. 1284-92. Alexandria, Va.: American Diabetes Association 10.2337/db07-1692
Conus, Sébastien; Simon, Hans-Uwe (2008). Cathepsins: key modulators of cell death and inflammatory responses. Biochemical pharmacology, 76(11), pp. 1374-82. New York, N.Y.: Elsevier 10.1016/j.bcp.2008.07.041
Ulrich, Martina; Petre, Alina; Youhnovski, Nikolay; Prömm, Franziska; Schirle, Markus; Schumm, Michael; Pero, Ralph S; Doyle, Alfred; Checkel, James; Kita, Hirohito; Thiyagarajan, Nethaji; Acharya, K Ravi; Schmid-Grendelmeier, Peter; Simon, Hans-Uwe; Schwarz, Heinz; Tsutsui, Masato; Shimokawa, Hiroaki; Bellon, Gabriel; Lee, James J; Przybylski, Michael; ... (2008). Post-translational tyrosine nitration of eosinophil granule toxins mediated by eosinophil peroxidase. Journal of biological chemistry, 283(42), pp. 28629-40. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M801196200
Straumann, Alex; Bussmann, Christian; Conus, Sébastien; Beglinger, Christoph; Simon, Hans-Uwe (2008). Anti-TNF-alpha (infliximab) therapy for severe adult eosinophilic esophagitis. Journal of allergy and clinical immunology, 122(2), pp. 425-7. St. Louis, Mo.: Mosby 10.1016/j.jaci.2008.06.012
Simon, Dagmar; Wittwer, Jennifer; Kostylina, Ganna; Buettiker, Urs; Simon, Hans-Uwe; Yawalkar, Nikhil (2008). Alefacept (lymphocyte function-associated molecule 3/IgG fusion protein) treatment for atopic eczema. Journal of allergy and clinical immunology, 122(2), pp. 423-4. St. Louis, Mo.: Mosby 10.1016/j.jaci.2008.06.010
von Gunten, Stephan; Simon, Hans-Uwe (2008). Natural anti-Siglec autoantibodies mediate potential immunoregulatory mechanisms: implications for the clinical use of intravenous immunoglobulins (IVIg). Autoimmunity reviews, 7(6), pp. 453-6. Amsterdam: Elsevier 10.1016/j.autrev.2008.03.015
Conus, Sébastien; Simon, Hans-Uwe (2008). General laboratory diagnostics of eosinophilic GI diseases. Best practice & research - clinical gastroenterology, 22(3), pp. 441-53. London: Baillière Tindall 10.1016/j.bpg.2007.09.003
Rothenberg, Marc E; Klion, Amy D; Roufosse, Florence E; Kahn, Jean Emmanuel; Weller, Peter F; Simon, Hans-Uwe; Schwartz, Lawrence B; Rosenwasser, Lanny J; Ring, Johannes; Griffin, Elaine F; Haig, Ann E; Frewer, Paul I H; Parkin, Jacqueline M; Gleich, Gerald J (2008). Treatment of patients with the hypereosinophilic syndrome with mepolizumab. New England journal of medicine NEJM, 358(12), pp. 1215-28. Waltham, Mass.: Massachusetts Medical Society MMS 10.1056/NEJMoa070812
Simon, Dagmar; Hösli, Susanne; Kostylina, Ganna; Yawalkar, Nikhil; Simon, Hans-Uwe (2008). Anti-CD20 (rituximab) treatment improves atopic eczema. Journal of allergy and clinical immunology, 121(1), pp. 122-8. St. Louis, Mo.: Mosby 10.1016/j.jaci.2007.11.016
Yousefi, Shida; Gold, Jeffrey A; Andina, Nicola; Lee, James J; Kelly, Ann M; Kozlowski, Evelyne; Schmid, Inès; Straumann, Alex; Reichenbach, Janine; Gleich, Gerald J; Simon, Hans-Uwe (2008). Catapult-like release of mitochondrial DNA by eosinophils contributes to antibacterial defense. Nature medicine, 14(9), pp. 949-53. New York, N.Y.: Nature Publishing Group 10.1038/nm.1855
Bousquet, J; Fokkens, W; Burney, P; Durham, S R; Bachert, C; Akdis, C A; Canonica, G W; Dahlen, S-E; Zuberbier, T; Bieber, T; Bonini, S; Bousquet, P J; Brozek, J L; Cardell, L-O; Crameri, R; Custovic, A; Demoly, P; van Wijk, R G; Gjomarkaj, M; Holland, C; ... (2008). Important research questions in allergy and related diseases: nonallergic rhinitis: a GA2LEN paper. Allergy, 63(7), pp. 842-53. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2008.01715.x
Bousquet, J; Bieber, T; Fokkens, W; Kowalski, M; Humbert, M; Niggemann, B; Simon, H-U; Cruz, A A; Haahtela, T (2008). In Allergy, 'A new day has begun'. Allergy, 63(6), pp. 631-3. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2008.01730.x
Straumann, Alex; Bussmann, Christian; Zuber, Markus; Vannini, Simone; Simon, Hans-Uwe; Schoepfer, Alain (2008). Eosinophilic esophagitis: analysis of food impaction and perforation in 251 adolescent and adult patients. Clinical gastroenterology and hepatology, 6(5), pp. 598-600. Philadelphia, Pa.: Elsevier 10.1016/j.cgh.2008.02.003
Berent-Maoz, B; Salemi, S; Mankuta, D; Simon, H-U; Levi-Schaffer, F (2008). TRAIL mediated signaling in human mast cells: the influence of IgE-dependent activation. Allergy, 63(3), pp. 333-40. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2007.01598.x
Klionsky, Daniel J; Abeliovich, Hagai; Agostinis, Patrizia; Agrawal, Devendra K; Aliev, Gjumrakch; Askew, David S; Baba, Misuzu; Baehrecke, Eric H; Bahr, Ben A; Ballabio, Andrea; Bamber, Bruce A; Bassham, Diane C; Bergamini, Ettore; Bi, Xiaoning; Biard-Piechaczyk, Martine; Blum, Janice S; Bredesen, Dale E; Brodsky, Jeffrey L; Brumell, John H; Brunk, Ulf T; ... (2008). Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy, 4(2), pp. 151-75. Austin, Tex.: Landes Bioscience
Bousquet, J; Bieber, T; Fokkens, W; Kowalski, M L; Humbert, M; Niggemann, B; Simon, H-U; Burney, P; van Cauwenberge, P; Zuberbier, T; Akdis, C A; Demoly, P (2008). Important questions in allergy: novel research areas. Allergy, 63(2), pp. 143-7. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2007.01615.x
Bousquet, J; Bieber, T; Fokkens, W; Humbert, M; Kowalski, M L; Niggemann, B; Simon, H-U; Schünemann, H (2008). Consensus statements, evidence-based medicine and guidelines in allergic diseases. Allergy, 63(1), pp. 1-4. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2007.01594.x
Huwiler, Andrea (2008). Antiarthrotic and Immunomodulatory Activity (Check index of the book for specific contributions). In: Vogel, Hans Gerhard (ed.) Drug Discovery and Evaluation: Pharmacological Assays, Vol 1 and 2 (pp. 1117-1190). Heidelberg: Springer Verlag 10.1007/978-3-540-70995-4_10
Simon, HU (2008). Hypereosinophilic syndromes. In: Kay AB, Kaplan AP (ed.) Allergy and Allergic Diseases, 2nd Edition (pp. 1802-1809). Malden, MA: Wiley-Blackwell Publishing
Yokoi, Hidenori; Choi, Oksoon H; Hubbard, Walter; Lee, Hyun-Sil; Canning, Brendan J; Lee, Hyun H; Ryu, Seung-Duk; von Gunten, Stephan; Bickel, Carol A; Hudson, Sherry A; Macglashan, Donald W; Bochner, Bruce S (2008). Inhibition of FcepsilonRI-dependent mediator release and calcium flux from human mast cells by sialic acid-binding immunoglobulin-like lectin 8 engagement. Journal of allergy and clinical immunology, 121(2), 499-505.e1. St. Louis, Mo.: Mosby 10.1016/j.jaci.2007.10.004
von Gunten, Stephan; Bochner, Bruce S (2008). Basic and clinical immunology of Siglecs. Annals of the New York Academy of Sciences, 1143, pp. 61-82. Boston, Mass.: Blackwell 10.1196/annals.1443.011
Wahn, V; Späth, P J (2008). Komplementdefekte, Kinder und Jugendmedizin. Kinder- und Jugendmedizin, 3(2008), pp. 179-184. Stuttgart: Schattauer
Wahn, V; Späth, P (2008). Pathogen safety of immunoglubulin preparations. In: Clinical Use of Immunoglobulins, 1st Edtition (pp. 29-50). Bremen et al.: UNI-MED
Constantinou, Thecla; Baumann, Fabrizio; Lacher, Markus D; Saurer, Susanne; Friis, Robert; Dharmarajan, Arun (2008). SFRP-4 abrogates Wnt-3a-induced beta-catenin and Akt/PKB signalling and reverses a Wnt-3a-imposed inhibition of in vitro mammary differentiation. Journal of molecular signaling, 3, p. 10. London: BioMed Central 10.1186/1750-2187-3-10
Scherr, C; Simon, M; Spranger, J; Baumgartner, S (2008). Test System Stability and Natural Variability of a Lemna Gibba L. Bioassay. PLoS ONE, 3(9), e3133. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0003133
Scaglioni, P. P.; Yung, T. M.; Choi, S. C.; Baldini, C.; Konstantinidou, Georgia; Pandolfi, P. P. (2008). CK2 mediates phosphorylation and ubiquitin-mediated degradation of the PML tumor suppressor. Molecular and cellular biochemistry, 316(1-2), pp. 149-154. Springer 10.1007/s11010-008-9812-7
Galiè, M; Konstantinidou, Georgia; Peroni, D; Scambi, I; Marchini, C; Lisi, V; Krampera, M; Magnani, P; Merigo, F; Montani, M; Boschi, F; Marzola, P; Orrù, R; Farace, P; Sbarbati, A; Amici, A (2008). Mesenchymal stem cells share molecular signature with mesenchymal tumor cells and favor early tumor growth in syngeneic mice. Oncogene, 27(18), pp. 2542-2551. Nature Publishing Group 10.1038/sj.onc.1210920
Salemi, Souzan; Yousefi, Shida; Lochmatter, Didier; Eblé, Andrée; Deladoëy, Johnny; Robinson, Iain C A F; Simon, Hans-Uwe; Mullis, Primus E (2007). Isolated autosomal dominant growth hormone deficiency: stimulating mutant GH-1 gene expression drives GH-1 splice-site selection, cell proliferation, and apoptosis. Endocrinology, 148(1), pp. 45-53. Chevy Chase, Md.: Endocrine Society 10.1210/en.2006-0772
Petkovic, Vibor; Salemi, Souzan; Vassella, Erik; Karamitopoulou-Diamantis, Evanthia; Meinhardt, Udo J; Flück, Christa E; Mullis, Primus E (2007). Leydig-cell tumour in children: variable clinical presentation, diagnostic features, follow-up and genetic analysis of four cases. Hormone research, 67(2), pp. 89-95. Basel: Karger 10.1159/000096356
Klawitter, S; Hofmann, L P; Pfeilschifter, J; Huwiler, A (2007). Extracellular nucleotides induce migration of renal mesangial cells by upregulating sphingosine kinase-1 expression and activity. British journal of pharmacology, 150(3), pp. 271-80. Oxford: Wiley-Blackwell 10.1038/sj.bjp.0706983
Rizzi, Mattia; Tschan, Mario P; Britschgi, Christian; Britschgi, Adrian; Hügli, Barbara; Grob, Tobias J; Leupin, Nicolas; Mueller, Beatrice U; Simon, Hans-Uwe; Ziemiecki, Andrew; Torbett, Bruce E; Fey, Martin F; Tobler, Andreas (2007). The death-associated protein kinase 2 is up-regulated during normal myeloid differentiation and enhances neutrophil maturation in myeloid leukemic cells. Journal of leukocyte biology, 81(6), pp. 1599-608. Bethesda, Md.: Society for Leukocyte Biology 10.1189/jlb.0606400
Yousefi, Shida; Simon, Hans-Uwe (2007). Apoptosis regulation by autophagy gene 5. Critical reviews in oncology, hematology, 63(3), pp. 241-4. Boca Raton, Fla.: Elsevier 10.1016/j.critirevonc.2007.06.005
Tsilimparis, N; Alevizakos, P; Yousefi, S; Hanack, U; Im Spring, B; Blank, B; Rückert, R I (2007). [Endovascular therapy of an abdominal aortic aneurysm in a renal transplant recipient]. Zentralblatt für Chirurgie, 132(3), 220-5; discussion 225-6. Stuttgart: Thieme 10.1055/s-2007-981162
White, Amy M; Banovac, Filip; Yousefi, Shadi; Slack, Rebecca S; Spies, James B (2007). Uterine fibroid embolization: the utility of aortography in detecting ovarian artery collateral supply. Radiology, 244(1), pp. 291-8. Oak Brook, Ill.: Radiological Society of North America RSNA 10.1148/radiol.2441060796
Tsilimparis, Nikolaos; Hanack, Ulrich; Yousefi, Sharom; Alevizakos, Pavlos; Rückert, Ralph I (2007). Cystic adventitial disease of the popliteal artery: an argument for the developmental theory. Journal of vascular surgery, 45(6), pp. 1249-52. Amsterdam: Elsevier 10.1016/j.jvs.2007.01.051
Hussain, Sajid; Plückthun, Andreas; Allen, Theresa M; Zangemeister-Wittke, Uwe (2007). Antitumor activity of an epithelial cell adhesion molecule targeted nanovesicular drug delivery system. Molecular cancer therapeutics, 6(11), pp. 3019-27. Philadelphia, Pa.: American Association for Cancer Research AACR 10.1158/1535-7163.MCT-07-0615
Giorgini, Simona; Trisciuoglio, Daniela; Gabellini, Chiara; Desideri, Marianna; Castellini, Laura; Colarossi, Cristina; Zangemeister-Wittke, Uwe; Zupi, Gabriella; Del Bufalo, Donatella (2007). Modulation of bcl-xL in tumor cells regulates angiogenesis through CXCL8 expression. Molecular cancer research, 5(8), pp. 761-71. Philadelphia, Pa.: American Association for Cancer Research AACR 10.1158/1541-7786.MCR-07-0088
Huwiler, Andrea; Zangemeister-Wittke, Uwe (2007). Targeting the conversion of ceramide to sphingosine 1-phosphate as a novel strategy for cancer therapy. Critical reviews in oncology, hematology, 63(2), pp. 150-9. Boca Raton, Fla.: Elsevier 10.1016/j.critrevonc.2007.04.010
Döll, Frauke; Pfeilschifter, Josef; Huwiler, Andrea (2007). Prolactin upregulates sphingosine kinase-1 expression and activity in the human breast cancer cell line MCF7 and triggers enhanced proliferation and migration. Endocrine-related cancer, 14(2), pp. 325-35. Bristol: BioScientifica Ltd. 10.1677/ERC-06-0050
Xin, Cuiyan; Ren, Shuyu; Eberhardt, Wolfgang; Pfeilschifter, Josef; Huwiler, Andrea (2007). Sphingosylphosphorylcholine acts in an anti-inflammatory manner in renal mesangial cells by reducing interleukin-1beta-induced prostaglandin E2 formation. Journal of lipid research, 48(9), pp. 1985-96. Bethesda, Md.: American Society for Biochemistry and Molecular Biology ASBMB 10.1194/jlr.M700077-JLR200
Ulrich, Sandra; Huwiler, Andrea; Loitsch, Stefan; Schmidt, Helmut; Stein, Jürgen M (2007). De novo ceramide biosynthesis is associated with resveratrol-induced inhibition of ornithine decarboxylase activity. Biochemical pharmacology, 74(2), pp. 281-9. New York, N.Y.: Elsevier 10.1016/j.bcp.2007.04.001
Doller, Anke; Huwiler, Andrea; Müller, Roswitha; Radeke, Heinfried H; Pfeilschifter, Josef; Eberhardt, Wolfgang (2007). Protein kinase C alpha-dependent phosphorylation of the mRNA-stabilizing factor HuR: implications for posttranscriptional regulation of cyclooxygenase-2. Molecular biology of the cell, 18(6), pp. 2137-48. Bethesda, Md.: American Society for Cell Biology 10.1091/mbc.E06-09-0850
Xin, C; Ren, S; Eberhardt, W; Pfeilschifter, J; Huwiler, A (2007). FTY720 suppresses interleukin-1beta-induced secretory phospholipase A2 expression in renal mesangial cells by a transcriptional mechanism. British journal of pharmacology, 150(7), pp. 943-50. Oxford: Wiley-Blackwell 10.1038/sj.bjp.0707171
Simon, Hans-Uwe; Cools, Jan (2007). Novel approaches to therapy of hypereosinophilic syndromes. Immunology and allergy clinics of North America, 27(3), pp. 519-27. Philadelphia, Pa.: Elsevier 10.1016/j.iac.2007.07.003
Hassan, Akmal S; Simon, Dagmar; Simon, Hans-Uwe; Braathen, Lasse R; Yawalkar, Nikhil (2007). Efalizumab-associated papular psoriasis. Archives of dermatology, 143(7), pp. 900-6. Chicago, Ill.: American Medical Association 10.1001/archderm.143.7.900
Simon, D; Braathen, L R; Simon, H-U (2007). Increased lipopolysaccharide-induced tumour necrosis factor-alpha, interferon-gamma and interleukin-10 production in atopic dermatitis. British journal of dermatology, 157(3), pp. 583-6. Oxford: Wiley-Blackwell 10.1111/j.1365-2133.2007.08050.x
Simon, Dagmar; Simon, Hans-Uwe (2007). Eosinophilic disorders. Journal of allergy and clinical immunology, 119(6), 1291-300; quiz 1301-2. St. Louis, Mo.: Mosby 10.1016/j.jaci.2007.02.010
von Gunten, Stephan; Vogel, Monique; Schaub, Alexander; Stadler, Beda M; Miescher, Sylvia; Crocker, Paul R; Simon, Hans-Uwe (2007). Intravenous immunoglobulin preparations contain anti-Siglec-8 autoantibodies. Journal of allergy and clinical immunology, 119(4), pp. 1005-11. St. Louis, Mo.: Mosby 10.1016/j.jaci.2007.01.023
Simon, D; Braathen, L R; Simon, H-U (2007). [Anti-interleukin-5 therapy for eosinophilic diseases]. Hautarzt, 58(2), 122, 124-7. Heidelberg: Springer-Verlag 10.1007/s00105-006-1273-x
Simon, Hans-Uwe; Seger, Reinhard (2007). Hyper-IgE syndrome associated with an IL-4-producing gamma/delta(+) T-cell clone. Journal of allergy and clinical immunology, 119(1), pp. 246-8. St. Louis, Mo.: Mosby 10.1016/j.jaci.2006.08.025
von Gunten, Stephan; Simon, Hans-Uwe (2007). Autophagic-like cell death in neutrophils induced by autoantibodies. Autophagy, 3(1), pp. 67-8. Austin, Tex.: Landes Bioscience
Salemi, Souzan; Aeschlimann, Andre; Wollina, Uwe; Gay, Renate E; Michel, Beat A; Gay, Steffen; Sprott, Haiko (2007). Up-regulation of delta-opioid receptors and kappa-opioid receptors in the skin of fibromyalgia patients. Arthritis & rheumatism, 56(7), pp. 2464-6. Hoboken, N.J.: Wiley-Blackwell 10.1002/art.22735
Simon, D; Simon, HU (2007). Reply - Eosinophilia in cholesterol atheroembolic disease. Journal of allergy and clinical immunology, 120(6), p. 1471. St. Louis, Mo.: Mosby 10.1016/j.jaci.2007.07.013
Yousefi, S; Simon, HU (2007). Taxol Therapy revisited. Blood, 110(2007), p. 3492. Washington, D.C.: American Society of Hematology 10.1182/blood-2007-08-105486
Zangemeister-Wittke, Uwe (2007). Krebsbehandlung mit Antisensemolekülen. Onkologe, 13(2007), pp. 256-262. Heidelberg: Springer-Medizin-Verlag
Spaeth, P; Wahn, V (2007). Komplementdefekte. Allergologie, 30(2007), pp. 99-105. München-Deisenhofen: Dustri-Verlag
Poehlau, D; Przuntek, H; Sailer, M; Bethke, M; Koehler, J; Koenig, N; Heesen, C; Spaeth, P (2007). Intravenous immunoglobulin in primary and secondary chronic progressive multiple sclerosis: a randomized placebo controlled multicentre study. Multiple sclerosis journal, 13(2007), pp. 1107-1117. London: Sage 10.1177/1352458507078400
Zangemeister-Wittke, Uwe (2007). Antisense molecules for targeted cancer therapy. Onkologe, 13(3), pp. 256-262. Springer-Medizin-Verlag 10.1007/s00761-006-1170-z
Zangemeister-Wittke, Uwe; Huwiler, Andrea (2006). Antisense targeting of Mcl-1 has therapeutic potential in gastric cancer. Cancer biology & therapy, 5(10), pp. 1355-1356. Georgetown, Tex.: Landes Bioscience 10.4161/cbt.5.10.3488
Huwiler, Andrea; Pfeilschifter, Josef (2006). Altering the sphingosine-1-phosphate/ceramide balance: a promising approach for tumor therapy. Current pharmaceutical design, 12(35), pp. 4625-35. Hilversum: Bentham Science Publishers 10.2174/138161206779010422
Huwiler, Andrea; Pfeilschifter, Josef (2006). Hypoxia and lipid signaling. Biological chemistry, 387(10-11), pp. 1321-1328. Berlin: Walter de Gruyter 10.1515/BC.2006.165
Huwiler, Andrea; Döll, Frauke; Ren, Shuyu; Klawitter, Sabine; Greening, Anna; Römer, Isolde; Bubnova, Svetlana; Reinsberg, Luise; Pfeilschifter, Josef (2006). Histamine increases sphingosine kinase-1 expression and activity in the human arterial endothelial cell line EA.hy 926 by a PKC-alpha-dependent mechanism. Biochimica and biophysica acta - molecular and cell biology of lipids, 1761(3), pp. 367-376. Biochimica and biophysica acta - molecular and cell biology of lipids: Elsevier 10.1016/j.bbalip.2006.02.007
Xin, Cuiyan; Ren, Shuyu; Eberhardt, Wolfgang; Pfeilschifter, Josef; Huwiler, Andrea (2006). The immunomodulator FTY720 and its phosphorylated derivative activate the Smad signalling cascade and upregulate connective tissue growth factor and collagen type IV expression in renal mesangial cells. British journal of pharmacology, 147(2), pp. 164-74. Oxford: Wiley-Blackwell 10.1038/sj.bjp.0706452
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Yousefi, Shida; Perozzo, Remo; Schmid, Inès; Ziemiecki, Andrew; Schaffner, Thomas; Scapozza, Leonardo; Brunner, Thomas; Simon, Hans-Uwe (2006). Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis. Nature cell biology, 8(10), pp. 1124-32. London: Nature Publishing Group 10.1038/ncb1482
Daryadel, Arezoo; Grifone, Remo Filippo; Simon, Hans-Uwe; Yousefi, Shida (2006). Apoptotic neutrophils release macrophage migration inhibitory factor upon stimulation with tumor necrosis factor-alpha. Journal of biological chemistry, 281(37), pp. 27653-61. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M604051200
Vassina, Ekatherina M; Yousefi, Shida; Simon, Dagmar; Zwicky, Caroline; Conus, Sébastien; Simon, Hans-Uwe (2006). cIAP-2 and survivin contribute to cytokine-mediated delayed eosinophil apoptosis. European journal of immunology, 36(7), pp. 1975-84. Weinheim: Wiley-VCH 10.1002/eji.200635943
Martinelli, S; Kostylina, G; Niggli, V; Baumann, C; Fey, M F; Wendel, H-G; Lowe, S W; Yousefi, S; Simon, H-U (2006). Targeting survivin via PI3K but not c-akt/PKB by anticancer drugs in immature neutrophils. Oncogene, 25(52), pp. 6915-23. Basingstoke, UK: Nature Publishing Group 10.1038/sj.onc.1209692
Salemi, Souzan; Yousefi, Shida; Eblé, Andrée; Deladoëy, Johnny; Mullis, Primus E (2006). Impact of del32-71-GH (exon 3 skipped GH) on intracellular GH distribution, secretion and cell viability: a quantitative confocal microscopy analysis. Hormone research, 65(3), pp. 132-41. Basel: Karger 10.1159/000091607
Nachbur, Ueli; Kassahn, Daniela; Yousefi, Shida; Legler, Daniel F; Brunner, Thomas (2006). Posttranscriptional regulation of Fas (CD95) ligand killing activity by lipid rafts. Blood, 107(7), pp. 2790-6. Washington, D.C.: American Society of Hematology 10.1182/blood-2005-07-2744
Simon, D; Straumann, A; Wenk, A; Spichtin, H; Simon, H-U; Braathen, L R (2006). Eosinophilic esophagitis in adults--no clinical relevance of wheat and rye sensitizations. Allergy, 61(12), pp. 1480-3. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2006.01224.x
Audigé, Annette; Urosevic, Mirjana; Schlaepfer, Erika; Walker, Russell; Powell, Doug; Hallenberger, Sabine; Joller, Helen; Simon, Hans-Uwe; Dummer, Reinhard; Speck, Roberto F (2006). Anti-HIV state but not apoptosis depends on IFN signature in CD4+ T cells. Journal of immunology, 177(9), pp. 6227-37. Bethesda, Md.: American Association of Immunologists
von Gunten, Stephan; Schaub, Alexander; Vogel, Monique; Stadler, Beda M; Miescher, Sylvia; Simon, Hans-Uwe (2006). Immunologic and functional evidence for anti-Siglec-9 autoantibodies in intravenous immunoglobulin preparations. Blood, 108(13), pp. 4255-9. Washington, D.C.: American Society of Hematology 10.1182/blood-2006-05-021568
Klion, Amy D; Bochner, Bruce S; Gleich, Gerald J; Nutman, Thomas B; Rothenberg, Marc E; Simon, Hans-Uwe; Wechsler, Michael E; Weller, Peter F; The Hypereosinophilic Syndromes Working Group, (2006). Approaches to the treatment of hypereosinophilic syndromes: a workshop summary report. Journal of allergy and clinical immunology, 117(6), pp. 1292-302. St. Louis, Mo.: Mosby 10.1016/j.jaci.2006.02.042
Simon, Dagmar; Lindberg, Raija L P; Kozlowski, Evelyne; Braathen, Lasse R; Simon, Hans-Uwe (2006). Epidermal caspase-3 cleavage associated with interferon-gamma-expressing lymphocytes in acute atopic dermatitis lesions. Experimental dermatology, 15(6), pp. 441-6. Oxford: Blackwell 10.1111/j.0906-6705.2006.00428.x
von Gunten, Stephan; Simon, Hans-Uwe (2006). Sialic acid binding immunoglobulin-like lectins may regulate innate immune responses by modulating the life span of granulocytes. FASEB journal, 20(6), pp. 601-5. Bethesda, Md.: Federation of American Societies for Experimental Biology 10.1096/fj.05-5401hyp
Simon, Hans-Uwe (2006). Cytokine and anti-cytokine therapy for asthma. Current allergy and asthma reports, 6(2), pp. 117-21. Philadelphia, Pa.: Springer 10.1007/s11882-006-0049-9
Simon, Hans-Uwe (2006). Molecules involved in the regulation of eosinophil apoptosis. Chemical immunology and allergy, 91, pp. 49-58. Basel: Karger
Vichalkovski, Anton; Kotevic, Ivana; Gebhardt, Niculina; Kaderli, Reto; Porzig, Hartmut (2006). Tyrosine kinase modulation of protein kinase C activity regulates G protein-linked Ca2+ signaling in leukemic hematopoietic cells. Cell calcium, 39(6), pp. 517-28. Amsterdam: Elsevier 10.1016/j.ceca.2006.03.001
Sigel, E; Baur, R; Boulineau, N; Minier, F (2006). Impact of subunit positioning on GABAA receptor function. Biochemical Society transactions, 34(Pt 5), pp. 868-71. London: Portland Press
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De Marchis, Gian Marco; Bürgi, Sibylle; Kientsch, Urs; Honegger, Ulrich E (2006). Vitamin E reduces antidepressant-related beta-adrenoceptor down-regulation in cultured cells. Comparable effects on St. John's wort and tricyclic antidepressant treatment. Planta medica, 72(15), pp. 1436-7. Stuttgart: Thieme 10.1055/s-2006-951727
Mühlebach, S F; Karlaganis, G; Honegger, U E (2006). Kinetic assessment of persistent halogenated xenobiotics in cell culture models: comparison of mono- and poly-halogenated compounds. Chemosphere, 62(11), pp. 1838-45. Kidlington, UK: Elsevier Science 10.1016/j.chemosphere.2005.07.041
Merendino, Anna M; Bucchieri, Fabio; Gagliardo, Rosalia; Daryadel, Arezoo; Pompeo, Flora; Chiappara, Giuseppina; Santagata, Roberta; Bellia, Vincenzo; David, Sabrina; Farina, Felicia; Davies, Donna E; Simon, Hans-Uwe; Vignola, Antonio M (2006). CD40 ligation protects bronchial epithelium against oxidant-induced caspase-independent cell death. American journal of respiratory cell and molecular biology, 35(2), pp. 155-64. New York, N.Y.: American Lung Association 10.1165/rcmb.2005-0433OC
Berent-Maoz, Beata; Piliponsky, Adrian M; Daigle, Isabelle; Simon, Hans-Uwe; Levi-Schaffer, Francesca (2006). Human mast cells undergo TRAIL-induced apoptosis. Journal of immunology, 176(4), pp. 2272-8. Bethesda, Md.: American Association of Immunologists
Hussain, Sajid; Plückthun, Andreas; Allen, Theresa M; Zangemeister-Wittke, Uwe (2006). Chemosensitization of carcinoma cells using epithelial cell adhesion molecule-targeted liposomal antisense against bcl-2/bcl-xL. Molecular cancer therapeutics, 5(12), pp. 3170-80. Philadelphia, Pa.: American Association for Cancer Research AACR 10.1158/1535-7163.MCT-06-0412
Mousavi-Shafaei, Parisa; Ziaee, Abed-Ali; Azizi, Ebrahim; Zangemeister-Wittke, Uwe (2006). Antisense-mediated melanoma inhibitor of apoptosis protein downregulation sensitizes G361 melanoma cells to cisplatin. Anti-cancer drugs, 17(9), pp. 1031-9. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/01.cad.0000231474.77159.e3
Kubetzko, Susanne; Balic, Ela; Waibel, Robert; Zangemeister-Wittke, Uwe; Plückthun, Andreas (2006). PEGylation and multimerization of the anti-p185HER-2 single chain Fv fragment 4D5: effects on tumor targeting. Journal of biological chemistry, 281(46), pp. 35186-201. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M604127200
Hopkins-Donaldson, Sally; Belyanskaya, Larisa L; Simões-Wüst, Ana Paula; Sigrist, Brigitte; Kurtz, Stefanie; Zangemeister-Wittke, Uwe; Stahel, Rolf (2006). p53-induced apoptosis occurs in the absence of p14(ARF) in malignant pleural mesothelioma. Neoplasia, 8(7), pp. 551-9. New York, N.Y.: Nature America 10.1593/neo.06148
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Yamanaka, Kazuki; Rocchi, Palma; Miyake, Hideaki; Fazli, Ladan; So, Alan; Zangemeister-Wittke, Uwe; Gleave, Martin E (2006). Induction of apoptosis and enhancement of chemosensitivity in human prostate cancer LNCaP cells using bispecific antisense oligonucleotide targeting Bcl-2 and Bcl-xL genes. BJU international, 97(6), pp. 1300-8. Oxford: Blackwell Science 10.1111/j.1464-410X.2006.06147.x
Bousquet, J; Bieber, T; Fokkens, W; Humbert, M; Kowalski, M; Niggemann, B; Simon, H-U (2006). Themes in allergy. Allergy, 61(1), pp. 1-2. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2006.01020.x
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