Brönnimann, Michael P.; Hirzberger, Lea; Keller, Peter M.; Gsell-Albert, Monika (2023). Antibacterial Effects of X-ray and MRI Contrast Media: An In Vitro Pilot Study. International journal of molecular sciences, 24(4), p. 3470. MDPI 10.3390/ijms24043470
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Some radiological contrast agents have been shown to have effects on bacterial growth. In this study, the antibacterial effect and mechanism of action of iodinated X-ray contrast agents (Ultravist 370, Iopamiro 300, Telebrix Gastro 300 and Visipaque) and complexed lanthanide MRI contrast solutions (MultiHance and Dotarem) were tested against six different microorganisms. Bacteria with high and low concentrations were exposed to media containing different contrast media for various lengths of time and at pH 7.0 and 5.5. The antibacterial effect of the media was examined in further tests using agar disk diffusion analysis and the microdilution inhibition method. Bactericidal effects were found for microorganisms at low concentrations and low pH. Reductions were confirmed for Staphylococcus aureus and Escherichia coli.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic, Interventional and Paediatric Radiology 04 Faculty of Medicine > Service Sector > Institute for Infectious Diseases 04 Faculty of Medicine > Service Sector > Institute for Infectious Diseases > General Bacteriology |
UniBE Contributor: |
Brönnimann, Michael, Hirzberger, Lea, Keller, Peter Michael, Gsell-Albert, Monika |
Subjects: |
500 Science > 570 Life sciences; biology 600 Technology > 610 Medicine & health |
ISSN: |
1422-0067 |
Publisher: |
MDPI |
Language: |
English |
Submitter: |
Maria de Fatima Henriques Bernardo |
Date Deposited: |
10 Feb 2023 08:31 |
Last Modified: |
10 Mar 2023 15:38 |
Publisher DOI: |
10.3390/ijms24043470 |
PubMed ID: |
36834880 |
BORIS DOI: |
10.48350/178578 |
URI: |
https://boris.unibe.ch/id/eprint/178578 |
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