Weidlinger, Susanna; Winterberger, Katja; Pape, Janna; Weidlinger, Magdalena; Janka, Heidrun; von Wolff, Michael; Stute, Petra (2023). Impact of estrogens on resting energy expenditure: A systematic review. Obesity reviews, 24(10), e13605. Wiley 10.1111/obr.13605
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The fear of weight gain is one of the main reasons for women not to initiate or to early discontinue hormonal contraception or menopausal hormone therapy. Resting energy expenditure is by far the largest component and the most important determinant of total energy expenditure. Given that low resting energy expenditure is a confirmed predictive factor for weight gain and consecutively for the development of obesity, research into the influence of sex steroids on resting energy expenditure is a particularly exciting area. The objective of this systematic review was to evaluate the effects of medication with natural and synthetic estrogens on resting energy expenditure in healthy normal weight and overweight women. Through complex systematic literature searches, a total of 10 studies were identified that investigated the effects of medication with estrogens on resting energy expenditure. Our results demonstrate that estrogen administration increases resting energy expenditure by up to +208 kcal per day in the context of contraception and by up to +222 kcal per day in the context of menopausal hormone therapy, suggesting a preventive effect of circulating estrogen levels and estrogen administration on weight gain and obesity development.
Item Type: |
Journal Article (Review Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Gynaecology 13 Central Units > Administrative Director's Office > University Library of Bern |
UniBE Contributor: |
Weidlinger, Susanna, Pape, Janna, Janka, Heidrun Ilonka, von Wolff, Michael, Stute, Petra |
Subjects: |
600 Technology > 610 Medicine & health 000 Computer science, knowledge & systems > 020 Library & information sciences |
ISSN: |
1467-7881 |
Publisher: |
Wiley |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
07 Aug 2023 09:36 |
Last Modified: |
07 Sep 2023 00:16 |
Publisher DOI: |
10.1111/obr.13605 |
PubMed ID: |
37544655 |
Uncontrolled Keywords: |
estrogen hormonal contraception menopausal hormone therapy resting energy expenditure |
BORIS DOI: |
10.48350/185245 |
URI: |
https://boris.unibe.ch/id/eprint/185245 |