Definitions of histological abnormalities in inflammatory bowel disease: an ECCO position paper.

Feakins, Roger; Borralho Nunes, Paulo; Driessen, Ann; Gordon, Ilyssa O; Zidar, Nina; Baldin, Pamela; Christensen, Britt; Danese, Silvio; Herlihy, Naoimh; Iacucci, Marietta; Loughrey, Maurice B; Magro, Fernando; Mookhoek, Aart; Svrcek, Magali; Rosini, Francesca (2024). Definitions of histological abnormalities in inflammatory bowel disease: an ECCO position paper. Journal of Crohn's & colitis, 18(2), pp. 175-191. Oxford University Press 10.1093/ecco-jcc/jjad142

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Histological assessment of endoscopic biopsies in inflammatory bowel disease [IBD] plays an important role in clinical management, investigative studies, and clinical trials. Scoring schemes consisting of multiple histological items and offering considerable precision are widely available. However, definitions of histological abnormalities are often inconsistent. Furthermore, interobserver variability for their recognition and assessment may be high. The European Crohn's and Colitis Organisation [ECCO] formed an expert panel to explore definitions of histological abnormalities in IBD, with the aim of improving the quality of diagnosis and facilitating development of scoring schemes. The process confirmed that the current definitions often have no evidence base and vary between sources. Using available evidence and expert knowledge, the panel produced a series of ECCO consensus position statements on histological features in IBD.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Service Sector > Institute of Pathology > Clinical Pathology
04 Faculty of Medicine > Service Sector > Institute of Pathology

UniBE Contributor:

Mookhoek, Aart

Subjects:

500 Science > 570 Life sciences; biology
600 Technology > 610 Medicine & health

ISSN:

1873-9946

Publisher:

Oxford University Press

Language:

English

Submitter:

Pubmed Import

Date Deposited:

23 Aug 2023 14:09

Last Modified:

28 Feb 2024 00:12

Publisher DOI:

10.1093/ecco-jcc/jjad142

PubMed ID:

37607017

Uncontrolled Keywords:

Crohn’s disease Inflammatory bowel disease definition histology ulcerative colitis

BORIS DOI:

10.48350/185663

URI:

https://boris.unibe.ch/id/eprint/185663

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