Buchwalder, Sébastien; Hersberger, Mario; Rebl, Henrike; Seemann, Susanne; Kram, Wolfgang; Hogg, Andreas; Tvedt, Lars G. W.; Clausen, Ingelin; Burger, Jürgen (2023). An Evaluation of Parylene Thin Films to Prevent Encrustation for a Urinary Bladder Pressure MEMS Sensor System. Polymers, 15(17), p. 3559. MDPI 10.3390/polym15173559
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Buchwalder_2023_An_Evaluation_of_Parylene_Thin_Films_to_Prevent_Encrustation_for_a_Urinary_Bladder_Pressure_MEMS_Sensor_System.pdf - Published Version Available under License Creative Commons: Attribution (CC-BY). Download (1MB) | Preview |
Recent developments in urological implants have focused on preventive strategies to mitigate encrustation and biofilm formation. Parylene, a conformal, pinhole-free polymer coating, has gained attention due to its high biocompatibility and chemical resistance, excellent barrier properties, and low friction coefficient. This study aims to evaluate the effectiveness of parylene C in comparison to a parylene VT4 grade coating in preventing encrustation on a urinary bladder pressure MEMS sensor system. Additionally, silicon oxide (SiOx) applied as a finish coating was investigated for further improvements. An in vitro encrustation system mimicking natural urine flow was used to quantify the formation of urinary stones. These stones were subsequently analyzed using Fourier transform infrared spectrometry (FTIR). Encrustation results were then discussed in relation to coating surface chemical properties. Parylene C and VT4 grades demonstrated a very low encrustation mass, making them attractive options for encrustation prevention. The best performance was achieved after the addition of a hydrophilic SiOx finish coating on parylene VT4 grade. Parylene-based encapsulation proved to be an outstanding solution to prevent encrustation for urological implants.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
08 Faculty of Science > School of Biomedical and Precision Engineering (SBPE) 08 Faculty of Science > School of Biomedical and Precision Engineering (SBPE) > Smart Surgical Instruments and Medical Devices |
Graduate School: |
Graduate School for Cellular and Biomedical Sciences (GCB) |
UniBE Contributor: |
Buchwalder, Sébastien, Hersberger, Mario Dante, Burger, Jürgen |
Subjects: |
600 Technology > 610 Medicine & health 600 Technology > 620 Engineering |
ISSN: |
2073-4360 |
Publisher: |
MDPI |
Language: |
English |
Submitter: |
Sébastien Buchwalder |
Date Deposited: |
29 Aug 2023 12:56 |
Last Modified: |
24 Sep 2023 02:33 |
Publisher DOI: |
10.3390/polym15173559 |
BORIS DOI: |
10.48350/185796 |
URI: |
https://boris.unibe.ch/id/eprint/185796 |
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