Age at diagnosis and loss of heterozygosity on chromosome 1p and 19q in oligodendroglial tumors

Hergersberg, M; Mariani, L; Vassella, E; Murtin, C; Weis, J; Moschopulos, M; Laeng, H; Landolt, H; Huber, A; Roelcke, U (2006). Age at diagnosis and loss of heterozygosity on chromosome 1p and 19q in oligodendroglial tumors. Journal of neuro-oncology, 80(2), pp. 215-7. Boston, Mass.: Springer 10.1007/s11060-006-9177-2

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The age distribution and incidence of loss of heterozygosity (LOH) of 1p and 19q was analyzed in 85 oligodendroglial tumors WHO II and III. The peak of tumor manifestation was in the age group of 35 to 55 years. There was no association between age at diagnosis and LOH incidence. We conclude that the prognostic effect of age on survival is not mediated by LOH 1p/19q.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurosurgery
04 Faculty of Medicine > Service Sector > Institute of Pathology

UniBE Contributor:

Mariani, Luigi and Vassella, Erik

ISSN:

0167-594X

ISBN:

16685464

Publisher:

Springer

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:45

Last Modified:

04 May 2014 23:13

Publisher DOI:

10.1007/s11060-006-9177-2

PubMed ID:

16685464

Web of Science ID:

000241521900017

URI:

https://boris.unibe.ch/id/eprint/18830 (FactScience: 1069)

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