Weir, Kristie Rebecca; Jungo, Katharina Tabea; Streit, Sven (2024). Older adults' adherence to medications and willingness to deprescribe: A sub-study of a randomized clinical trial. British journal of clinical pharmacology, 90(3), pp. 905-911. Wiley 10.1111/bcp.15966
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Weir_BrJClinPharmacol_2023_AAM.pdf - Accepted Version Available under License Creative Commons: Attribution (CC-BY). Download (935kB) | Preview |
Our study investigated the association between patients' willingness to have medications deprescribed and medication adherence. This longitudinal sub-study of the 'Optimizing PharmacoTherapy In the Multimorbid Elderly in Primary CAre' (OPTICA) trial, a cluster randomized controlled trial, took place in Swiss primary care settings. Participants were aged ≥65 years and over, with ≥3 chronic conditions, and ≥5 regular medications. At baseline the 'revised Patient Attitudes Towards Deprescribing' (rPATD) questionnaire was measured. The A14-scale measured adherence (self-report) at the 12-month follow-up. Multilevel linear regression analyses adjusted for baseline variables were performed. Of the 298 participants, 45% were women and the median age was 78. Participants reported a high level of adherence and willingness to have medications deprescribed. We did not find evidence for an association between patients' willingness to deprescribe and medication adherence. Further research is needed to explore the relationship between these concepts and to inform collaborative decisions about medicines in the context of polypharmacy.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Medical Education > Institute of General Practice and Primary Care (BIHAM) |
UniBE Contributor: |
Weir, Kristie Rebecca, Jungo, Katharina Tabea, Streit, Sven |
Subjects: |
600 Technology > 610 Medicine & health 300 Social sciences, sociology & anthropology > 360 Social problems & social services |
ISSN: |
0306-5251 |
Publisher: |
Wiley |
Funders: |
[4] Swiss National Science Foundation |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
13 Nov 2023 15:48 |
Last Modified: |
29 Feb 2024 08:31 |
Publisher DOI: |
10.1111/bcp.15966 |
PubMed ID: |
37953525 |
Additional Information: |
Kristie Rebecca Weir and Katharina Tabea Jungo shared first authorship. Sven Streit is the principal investigator. |
Uncontrolled Keywords: |
attitudes comorbidity deprescribing polypharmacy prescription |
BORIS DOI: |
10.48350/188849 |
URI: |
https://boris.unibe.ch/id/eprint/188849 |
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