Sellar collision tumor involving pituitary gonadotroph adenoma and chondroma: a potential clinical diagnosis

Sahli, Rahel; Christ, Emanuel; Kuhlen, Dominique; Giger, Olivier; Vajtai, Istvan (2011). Sellar collision tumor involving pituitary gonadotroph adenoma and chondroma: a potential clinical diagnosis. Pituitary, 14(4), pp. 405-408. Norwell, Mass.: Springer US; http://www.springer-ny.com 10.1007/s11102-009-0199-6

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We report on a 74-year-old male patient who presented with progressive neuroophthalmologic symptoms soon after the administration of a long-acting gonadotropin-releasing hormone agonist for treatment of a prostate cancer. Imaging revealed a destructively growing and extensively calcified sellar mass inconsistent with a pituitary adenoma. A transseptal transsphenoidal tumor mass reduction yielded a histological diagnosis of a collision tumor comprised of a gonadotroph adenoma intermingled with osteochondroma. We discuss a potential causal relationship between the administration of the long-acting gonadotropin-releasing hormone agonist and the sudden appearance of the previously unsuspected sellar lesion. Although the association of these two tumors is very likely coincidental, the possibility of causal relationship is addressed.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Service Sector > Institute of Pathology
04 Faculty of Medicine > Service Sector > Institute of Pathology > Clinical Pathology
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurosurgery
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Endocrinology, Diabetology and Clinical Nutrition

UniBE Contributor:

Sahli, Rahel Gerda; Christ, Emanuel; Kuhlen, Dominique; Giger, Olivier and Vajtai, Istvan

Subjects:

500 Science > 570 Life sciences; biology
600 Technology > 610 Medicine & health

ISSN:

1386-341X

ISBN:

19760170

Publisher:

Springer US; http://www.springer-ny.com

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:07

Last Modified:

25 Oct 2019 02:19

Publisher DOI:

10.1007/s11102-009-0199-6

PubMed ID:

19760170

Web of Science ID:

000300349800021

BORIS DOI:

10.7892/boris.19

URI:

https://boris.unibe.ch/id/eprint/19 (FactScience: 165647)

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