Successful Allergen-Specific Immunotherapy: Induction of Unresponsiveness by 'Vaccination'.

Bachmann, Martin F; Vogel, Monique; Speiser, Daniel E (2023). Successful Allergen-Specific Immunotherapy: Induction of Unresponsiveness by 'Vaccination'. Vaccines, 11(12) MDPI 10.3390/vaccines11121852

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The mechanisms of action of allergen-specific immunotherapy (AIT) are often referred to as the induction of 'tolerance'. However, immunological 'tolerance' is defined as an alteration in the function or composition of immune cells. For AIT, this is not always the case, because it can also induce allergen-specific IgG antibodies that block allergic responses. To include all possible mechanisms that may mediate successful AIT, it is advantageous to use the scientific term 'unresponsiveness' instead of 'tolerance'. In praxis, the term 'vaccination' is also appropriate, as AIT medications are specialized vaccines.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Rheumatology and Immunology
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR)
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Rheumatologie
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Rheumatologie

UniBE Contributor:

Bachmann, Martin (B), Vogel, Monique, Speiser, Daniel Ernst

Subjects:

600 Technology > 610 Medicine & health

ISSN:

2076-393X

Publisher:

MDPI

Language:

English

Submitter:

Pubmed Import

Date Deposited:

28 Dec 2023 10:58

Last Modified:

29 Dec 2023 05:59

Publisher DOI:

10.3390/vaccines11121852

PubMed ID:

38140255

BORIS DOI:

10.48350/190747

URI:

https://boris.unibe.ch/id/eprint/190747

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