Bachmann, Martin F; Vogel, Monique; Speiser, Daniel E (2023). Successful Allergen-Specific Immunotherapy: Induction of Unresponsiveness by 'Vaccination'. Vaccines, 11(12) MDPI 10.3390/vaccines11121852
|
Text
vaccines-11-01852.pdf - Published Version Available under License Creative Commons: Attribution (CC-BY). Download (667kB) | Preview |
The mechanisms of action of allergen-specific immunotherapy (AIT) are often referred to as the induction of 'tolerance'. However, immunological 'tolerance' is defined as an alteration in the function or composition of immune cells. For AIT, this is not always the case, because it can also induce allergen-specific IgG antibodies that block allergic responses. To include all possible mechanisms that may mediate successful AIT, it is advantageous to use the scientific term 'unresponsiveness' instead of 'tolerance'. In praxis, the term 'vaccination' is also appropriate, as AIT medications are specialized vaccines.
Item Type: |
Journal Article (Further Contribution) |
---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Rheumatology and Immunology 04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) 04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Rheumatologie 04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Rheumatologie |
UniBE Contributor: |
Bachmann, Martin (B), Vogel, Monique, Speiser, Daniel Ernst |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
2076-393X |
Publisher: |
MDPI |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
28 Dec 2023 10:58 |
Last Modified: |
29 Dec 2023 05:59 |
Publisher DOI: |
10.3390/vaccines11121852 |
PubMed ID: |
38140255 |
BORIS DOI: |
10.48350/190747 |
URI: |
https://boris.unibe.ch/id/eprint/190747 |