Trachsel, Christa (2023). Two Years after Coxiella burnetii Detection: Pathogen Shedding and Phase-Specific Antibody Response in Three Dairy Goat Herds. (Dissertation)
Full text not available from this repository. (Request a copy)The infection dynamics of Coxiella (C.) burnetii were investigated in three dairy goat herds (A, B, and C) 2 years after the first pathogen detection. A total of 28 and 29 goats from herds A and B, and 35 goats from herd C, were examined. Sera were analyzed on three sampling dates using phase-specific serology. Pathogen shedding was assessed using post-partum vaginal swabs and monthly bulk tank milk (BTM) samples. Dust samples from a barn and milking parlor were also collected monthly. These samples were analyzed with PCR (target IS1111). In herd A, individual animals tested seropositive, while vaginal swabs, BTM, and most dust samples tested negative. Herds B and C exhibited high IgG phase I activity, indicating a past infection. In herd B, approximately two-thirds of the goats shed C. burnetii with vaginal mucus, and irregular positive results were obtained from BTM. Herd C had two positive goats based on vaginal swabs, and BTM tested positive once. Dust samples from herds B and C contained C. burnetii DNA, with higher quantities typically found in samples from the milking parlor. This study highlights the different infection dynamics in three unvaccinated dairy goat herds and the potential use of dust samples as a supportive tool to detect C. burnetii at the herd level.
Item Type: |
Thesis (Dissertation) |
|---|---|
Division/Institute: |
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) 05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > Clinic for Ruminants |
UniBE Contributor: |
Trachsel, Christa, Hirsbrunner, Gabriela, Zanolari, Patrik |
Subjects: |
600 Technology > 630 Agriculture 500 Science > 590 Animals (Zoology) 600 Technology > 610 Medicine & health |
Language: |
English |
Submitter: |
Nathalie Viviane Zollinger |
Date Deposited: |
11 Jan 2024 08:45 |
Last Modified: |
11 Jan 2024 08:45 |
Additional Information: |
PMID: 37835654 PMCID: PMC10571745 DOI: 10.3390/ani13193048 |
URI: |
https://boris.unibe.ch/id/eprint/191444 |
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