Tisch, Carmen; Ernst, Daniel; Falke, Monika; Speicher, Philip; Ziaka, Mairi (2024). Systemic embolization due to non-bacterial thrombotic endocarditis: An autopsy case report and mini review of the literature. SAGE open medical case reports, 12(2050313X241229576) Sage 10.1177/2050313X241229576
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tisch-et-al-2024-systemic-embolization-due-to-non-bacterial-thrombotic-endocarditis-an-autopsy-case-report-and-mini.pdf - Published Version Available under License Creative Commons: Attribution-Noncommercial (CC-BY-NC). Download (446kB) | Preview |
Nonbacterial thrombotic endocarditis is a rare, non-infectious complication associated with hypercoagulable states, such as malignancies and autoimmune diseases. Due to the difficulty distinguishing marantic endocarditis from infective endocarditis, the diagnosis is often delayed or even a postmortem finding. We present the case of a 70-year-old Caucasian female with marantic endocarditis secondary to metastatic duodenal adenocarcinoma. The patient presented with a short history of memory deficits, personality disturbances, and left homonymous hemianopia. Diffusion-weighted magnetic resonance imaging showed multi-territorial bihemispheric cerebral infarctions. Transthoracic echocardiography revealed native mitral valve endocarditis, and serial blood cultures remained negative. Despite antibiotic therapy, the patient's condition continuously deteriorated, and she died within 3 weeks after her initial presentation. Postmortem examination showed a non-bacterial thrombotic endocarditis. Early clinical suspicion and prompt diagnosis are of decisive importance for the survival of the patients.
Item Type: |
Journal Article (Further Contribution) |
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Division/Institute: |
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Medical Oncology 04 Faculty of Medicine > Service Sector > Institute of Pathology |
UniBE Contributor: |
Falke, Monika Juliana, Speicher, Philip Alan |
Subjects: |
600 Technology > 610 Medicine & health 500 Science > 570 Life sciences; biology |
ISSN: |
2050-313X |
Publisher: |
Sage |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
01 Feb 2024 09:04 |
Last Modified: |
02 Feb 2024 02:30 |
Publisher DOI: |
10.1177/2050313X241229576 |
PubMed ID: |
38292877 |
Uncontrolled Keywords: |
Marantic endocarditis embolic complications hypercoagulable states malignancies nonbacterial thrombotic endocarditis postmortem diagnosis |
BORIS DOI: |
10.48350/192297 |
URI: |
https://boris.unibe.ch/id/eprint/192297 |
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