Benouhiba, Amine; Walter, Armando; Jahren, Silje Ekroll; Martinez, Thomas; Clavica, Francesco; Heinisch, Paul Philipp; Obrist, Dominik; Civet, Yoan; Perriard, Yves (2024). Dielectric elastomer Actuator-Based valveless pump as fontan failure assist device: Introduction and preliminary study. Interdisciplinary cardiovascular and thoracic surgery, 38(4) Oxford University Press 10.1093/icvts/ivae041
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OBJECTIVES
Fontan failure refers to a condition in which the Fontan circulation, a surgical procedure used to treat certain congenital heart defects, becomes insufficient, leading to compromised cardiac function and potential complications. This in vitro study therefore investigates the feasibility of bladeless impedance-driven cavopulmonary assist device via dielectric elastomer actuator (DEA) as a means to address Fontan failure.
METHODS
A cavopulmonary assist device, constructed using DEA technologies and employing the impedance pump concept, is subjected to in vitro testing within a closed-loop setup. This study aims to assess the device's functionality and performance under controlled conditions, providing valuable insights into its potential application as a cavopulmonary assistive technology.
RESULTS
The DEA-based pump, measuring 50 mm in length and 30 mm in diameter, is capable of achieving substantial flow rates within a closed-loop setup, reaching up to 1.20 L/min at an activation frequency of 4 Hz. It also provides a broad range of working internal pressures (less than 10 mmHg to more than 20 mmHg). Lastly, the properties of the flow (direction, magnitude, etc) can be controlled by adjusting the input signal parameters (frequency, amplitude, etc).
CONCLUSIONS
In summary, the results suggests that the valveless impedance-driven pump utilizing DEA technology is promising in the context of cavopulmonary assist devices. Further research and development in this area may lead to innovative and potentially more effective solutions for assisting the right heart, ultimately benefiting patients with heart-related health issues overall, with a particular focus on those experiencing Fontan failure.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research > ARTORG Center - Cardiovascular Engineering (CVE) 10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research |
UniBE Contributor: |
Jahren, Silje Ekroll, Clavica, Francesco, Obrist, Dominik |
Subjects: |
600 Technology > 610 Medicine & health 500 Science > 570 Life sciences; biology |
ISSN: |
2753-670X |
Publisher: |
Oxford University Press |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
27 Mar 2024 11:58 |
Last Modified: |
10 Apr 2024 00:17 |
Publisher DOI: |
10.1093/icvts/ivae041 |
PubMed ID: |
38514398 |
Uncontrolled Keywords: |
Fontan failure cavopulmonary assist device congenital heart defect valveless pumping |
BORIS DOI: |
10.48350/194624 |
URI: |
https://boris.unibe.ch/id/eprint/194624 |
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