Kokornaczyk, Maria Olga; Acuña, Carlos; Mier Y Terán, Alfonso; Castelán, Mario; Baumgartner, Stephan (2024). Vortex-like vs. turbulent mixing of a Viscum album preparation affects crystalline structures formed in dried droplets. Scientific Reports, 14(12965) Nature Publishing Group 10.1038/s41598-024-63797-z
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Various types of motion introduced into a solution can affect, among other factors, the alignment and positioning of molecules, the agglomeration of large molecules, oxidation processes, and the production of microparticles and microbubbles. We employed turbulent mixing vs. laminar flow induced by a vortex vs. diffusion-based mixing during the production of Viscum album Quercus L. 10-3 following the guidelines for manufacturing homeopathic preparations. The differently mixed preparation variants were analyzed using the droplet evaporation method. The crystalline structures formed in dried droplets were photographed and analyzed using computer-supported image analysis and deep learning. Computer-supported evaluation and deep learning revealed that the patterns of the variant succussed under turbulence are characterized by lower complexity, whereas those obtained from the vortex-mixed variant are characterized by greater complexity compared to the diffusion-based mixed control variant. The droplet evaporation method could provide a relatively inexpensive means of testing the effects of liquid flow and serve as an alternative to currently used methods.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Medical Education > Institute of Complementary and Integrative Medicine (IKIM) |
UniBE Contributor: |
Kokornaczyk, Maria Olga, Baumgartner, Stephan |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
2045-2322 |
Publisher: |
Nature Publishing Group |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
06 Jun 2024 12:53 |
Last Modified: |
06 Jun 2024 13:01 |
Publisher DOI: |
10.1038/s41598-024-63797-z |
PubMed ID: |
38839929 |
Uncontrolled Keywords: |
Crystallization Deep-learning Droplet evaporation Homeopathy Turbulent and laminar flow |
BORIS DOI: |
10.48350/197618 |
URI: |
https://boris.unibe.ch/id/eprint/197618 |
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