Photochemically induced RNA and DNA abasic sites

Küpfer, Pascal A.; Leumann, Christian J. (2007). Photochemically induced RNA and DNA abasic sites. Nucleosides, nucleotides & nucleic acids, 26(8-9), pp. 1177-1180. Philadelphia, Pa.: Taylor & Francis 10.1080/15257770701527711

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Two phosphoramidite building blocks were synthesized that can easily be deprotected by UV light to reveal natural abasic sites in oligoribonucleotides as well as in oligodeoxyribonucleotides. Another building block which releases a 2 ′-O-methylated abasic site upon UV radiation is also described.

Item Type:

Journal Article (Original Article)

Division/Institute:

08 Faculty of Science > Departement of Chemistry and Biochemistry

UniBE Contributor:

Küpfer, Pascal and Leumann, Christian

Subjects:

500 Science > 570 Life sciences; biology
500 Science > 540 Chemistry

ISSN:

1525-7770

Publisher:

Taylor & Francis

Language:

English

Submitter:

Christian Leumann

Date Deposited:

04 Oct 2013 14:53

Last Modified:

10 Aug 2015 10:57

Publisher DOI:

10.1080/15257770701527711

Web of Science ID:

000251875400063

BORIS DOI:

10.7892/boris.22454

URI:

https://boris.unibe.ch/id/eprint/22454 (FactScience: 34752)

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