Küpfer, Pascal

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Willi, Jessica; Küpfer, Pascal; Evéquoz, Damien; Fernandez, Guillermo; Katz, Assaf; Leumann, Christian; Polacek, Norbert (2018). Oxidative stress damages rRNA inside the ribosome and differentially affects the catalytic center. Nucleic acids research, 46(4), pp. 1945-1957. Information Retrieval Ltd. 10.1093/nar/gkx1308


Koch, Miriam; Küpfer, Pascal; Leumann, Christian; Polacek, Norbert; Willi, Jessica (9 July 2016). Oxidized bases in the ribosome's peptidyl transferase center and their effects on translation (Unpublished). In: EMBO Conference Ribosome – Structure and Function 2016. Strasbourg, France. 06.-10.07.2016.


Calabretta, Alessandro; Küpfer, Pascal A.; Leumann, Christian J. (2015). The effect of RNA base lesions on mRNA translation. Nucleic acids research, 43(9), pp. 4713-4720. Information Retrieval Ltd. 10.1093/nar/gkv377


Küpfer, Pascal A.; Leumann, Christian J. (2014). Oxidative Damage on RNA Nucleobases. In: Erdmann, Volker A.; Markiewicz, Wojciech T.; Barciszewski, Jan (eds.) Chemical Biology of Nucleic Acids. RNA Technologies (pp. 75-94). Heidelberg: Springer 10.1007/978-3-642-54452-1_5


Tanakaa, Mikiei; Jaruga, Pawel; Küpfer, Pascal A.; Leumann, Christian J.; Dizdaroglu, Miral; Sonntag, William E.; Chock, P. Boon (2012). RNA oxidation catalyzed by cytochrome c leads to its depurination and cross-linking, which may facilitate cytochrome c release from mitochondria. Free radical biology & medicine, 53(4), pp. 854-862. San Diego, Calif.: Elsevier 10.1016/j.freeradbiomed.2012.05.044


Tanaka, Mikiei; Han, Song; Küpfer, Pascal A.; Leumann, Christian J.; Sonntag, William E. (2011). Quantification of oxidized levels of specific RNA species using an aldehyde reactive probe. Analytical biochemistry, 417(1), pp. 142-148. San Diego, Calif.: Elsevier 10.1016/j.ab.2011.05.038

Tanaka, Mikiei; Song, Han; Küpfer, Pascal A.; Leumann, Christian J.; Sonntag, William E. (2011). An assay for RNA oxidation induced abasic sites using the Aldehyde Reactive Probe. Free radical research, 45(2), pp. 237-247. London: Informa Healthcare 10.3109/10715762.2010.535529

Küpfer, Pascal A.; Leumann, Christian J. (2011). Synthesis, base pairing properties and trans-lesion synthesis by reverse transcriptases of oligoribonucleotides containing the oxidatively damaged base 5-hydroxycytidine. Nucleic acids research, 39(21), pp. 9422-9432. London: Oxford University Press 10.1093/nar/gkr673


Küpfer, Pascal A.; Crey-Desbiolles, Caroline; Leumann, Christian J. (2007). Trans-lesion synthesis and RNase H activity by reverse transcriptases on a true abasic RNA template. Nucleic acids research, 35(20), pp. 6846-6853. London: Information Retrieval Ltd. 10.1093/nar/gkm767

Küpfer, Pascal A.; Leumann, Christian J. (2007). Photochemically induced RNA and DNA abasic sites. Nucleosides, nucleotides & nucleic acids, 26(8-9), pp. 1177-1180. Philadelphia, Pa.: Taylor & Francis 10.1080/15257770701527711


Küpfer, Pascal A.; Leumann, Christian J. (2006). The chemical stability of abasic RNA compared to abasic DNA. Nucleic acids research, 35(1), pp. 58-68. London: Oxford University Press 10.1093/nar/gkl948


Küpfer, Pascal A.; Leumann, Christian J. (2005). RNA abasic sites: preparation and trans-lesion synthesis by HIV-1 reverse transcriptase. ChemBioChem, 6(11), pp. 1970-1973. Wiley-VCH 10.1002/cbic.200500204

Mosimann, Markus; Küpfer, Pascal A.; Leumann, Christian J. (2005). Synthesis and incorporation into DNA of a chemically stable, functional abasic site analogue. Organic letters, 7(23), pp. 5211-5214. American Chemical Society 10.1021/ol052045g

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