Pleomorphic adenoma of the parotid gland: histopathologic analysis of the capsular characteristics of 218 tumors

Zbären, Peter; Stauffer, Edouard (2007). Pleomorphic adenoma of the parotid gland: histopathologic analysis of the capsular characteristics of 218 tumors. Head & neck - journal for the sciences and specialties of the head and neck, 29(8), pp. 751-7. New York, N.Y.: J. Wiley 10.1002/hed.20569

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BACKGROUND: Histopathologic features of the capsule may have an impact on the recurrence rate of pleomorphic adenomas. METHODS: Retrospective (n = 154) and prospective (n = 64) histologic analysis of the capsular characteristics such as incompleteness, tumor penetration, pseudopodia, and satellite tumors of 218 pleomorphic adenomas. RESULTS: In 160 of the 218 (73%) pleomorphic adenomas, 1 or more capsular characteristics such as incomplete capsule (33%), capsule penetration (26%), pseudopodia (40%), and satellite nodules (13%) were detected. Incomplete capsule and satellite tumors were most frequently seen in the stroma-rich (myxoid) subtype. Capsular penetration and pseudopodia were significantly more common in the prospective group than in the retrospective group (p < .05/<.05). CONCLUSION: Pseudopodia and satellite tumors were more common than reported in the literature. If left in the surrounding salivary gland tissue at surgery, they can lead to recurrences of pleomorphic adenomas of the parotid gland.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ear, Nose and Throat Disorders (ENT)
04 Faculty of Medicine > Service Sector > Institute of Pathology

UniBE Contributor:

Zbären, Peter and Stauffer, Edouard Jean

ISSN:

1043-3074

ISBN:

17252593

Publisher:

J. Wiley

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:55

Last Modified:

05 Feb 2016 06:41

Publisher DOI:

10.1002/hed.20569

PubMed ID:

17252593

Web of Science ID:

000248535700006

URI:

https://boris.unibe.ch/id/eprint/23272 (FactScience: 40786)

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