[Malignant lymphoma of the prostate--diagnosis on the second biopsy]

Vetsch, Gabi; Baumann, Christa K; Kläy, Marco; Leupin, Nicolas; Rentsch, Cyrill; Mueller-Garamvölgyi, Esther; Bürgi, Ulrich; Schiemann, Uwe (2008). [Malignant lymphoma of the prostate--diagnosis on the second biopsy]. Medizinische Klinik, 103(4), pp. 245-8. München: Urban & Vogel 10.1007/s00063-008-1034-y

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BACKGROUND: Malignant lymphoma of the prostate is rare. In the literature, about 165 cases with either a primary lymphoma of the prostate or secondary infiltration of the prostate by a lymphoma are described. CASE REPORT: The case of a 59-year-old patient with an irregular tumor in the prostatic region, but normal prostate-specific antigen (PSA), a fracture in the vertebral column and a bilateral enlargement of the suprarenal glands is presented. Repetitive prostate biopsy revealed the diagnosis of a diffuse large B cell lymphoma. Further staging examinations gave hints to an epidural infiltration. A polychemotherapy including intrathecal drug applications was initiated. Staging after four therapeutic cycles already showed good partial remission of all lymphoma manifestations. After two further therapeutic cycles, a CT scan showed a small rest of prostatic bulk, but PET-CT did not detect vital lymphatic tissue (complete remission). CONCLUSION: In cases of irregular prostatic enlargements, carcinoma has to be considered as the most frequent diagnosis. Nevertheless, also a solitary lymphoma or infiltration of the prostate by a systemic lymphoma has to be taken into account, especially if the PSA value is in the normal range.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Medical Oncology
04 Faculty of Medicine > Service Sector > Institute of Pathology
04 Faculty of Medicine > Department of General Internal Medicine (DAIM) > Clinic of General Internal Medicine
04 Faculty of Medicine > Department of General Internal Medicine (DAIM) > Clinic of General Internal Medicine > Centre of Competence for General Internal Medicine

UniBE Contributor:

Baumann, Christa Katharina; Mueller, Esther; Bürgi, Ulrich and Schiemann, Uwe Kurt

ISSN:

0723-5003

ISBN:

18484209

Publisher:

Urban & Vogel

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 15:01

Last Modified:

26 Jun 2018 14:38

Publisher DOI:

10.1007/s00063-008-1034-y

PubMed ID:

18484209

Web of Science ID:

000255277700008

BORIS DOI:

10.7892/boris.26567

URI:

https://boris.unibe.ch/id/eprint/26567 (FactScience: 73511)

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