Donor-to-host transmission of Candida glabrata to both recipients of corneal transplants from the same donor

Tappeiner, Christoph; Goldblum, David; Zimmerli, Stefan; Fux, Christoph; Frueh, Beatrice E (2009). Donor-to-host transmission of Candida glabrata to both recipients of corneal transplants from the same donor. Cornea, 28(2), pp. 228-30. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/ICO.0b013e318183a3e3

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PURPOSE: To report 2 cases of exogenous Candida glabrata endophthalmitis after penetrating keratoplasty in recipients of corneas from the same donor transplanted on the same day. METHODS: Case reports with ophthalmologic, electron microscopic, and microbiological findings including fungal strain analysis. RESULTS: Two patients developed fungal keratitis and endophthalmitis caused by the same C. glabrata strain within 1 day after penetrating keratoplasty of corneas from the same donor on the same day. Donor-to-host transmission was postulated when eye bank sterility checks were repeatedly negative. CONCLUSIONS: A short death-to-harvesting time, routine donor rim cultures, and respecting of a time interval before transplantation may provide an additional safety feature in dealing with corneal tissue from high-risk donors.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ophthalmology
04 Faculty of Medicine > Service Sector > Institute for Infectious Diseases
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Infectiology

UniBE Contributor:

Tappeiner, Christoph; Zimmerli, Stefan; Fux, Christoph Andreas and Früh Epstein, Beatrice

ISSN:

0277-3740

ISBN:

19158573

Publisher:

Lippincott Williams & Wilkins

Language:

English

Submitter:

Christoph Tappeiner

Date Deposited:

04 Oct 2013 15:05

Last Modified:

04 May 2014 23:20

Publisher DOI:

10.1097/ICO.0b013e318183a3e3

PubMed ID:

19158573

Web of Science ID:

000262844100023

URI:

https://boris.unibe.ch/id/eprint/28248 (FactScience: 119011)

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