Serduc, Raphaël; Bräuer-Krisch, Elke; Bouchet, Audrey; Renaud, Luc; Brochard, Thierry; Bravin, Alberto; Laissue, Jean Albert; Le Duc, Géraldine (2009). First trial of spatial and temporal fractionations of the delivered dose using synchrotron microbeam radiation therapy. Journal of synchrotron radiation, 16(Pt 4), pp. 587-90. Oxford: Blackwell Publishing 10.1107/S0909049509012485
Full text not available from this repository.The technical feasibility of temporal and spatial fractionations of the radiation dose has been evaluated using synchrotron microbeam radiation therapy for brain tumors in rats. A significant increase in lifespan (216%, p < 0.0001) resulted when three fractions of microbeam irradiation were applied to the tumor through three different ports, orthogonal to each other, at 24 h intervals. However, there were no long-term survivors, and immunohistological studies revealed that 9 L tumors were not entirely ablated.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Service Sector > Institute of Pathology |
UniBE Contributor: |
Laissue, Jean |
ISSN: |
0909-0495 |
ISBN: |
19535875 |
Publisher: |
Blackwell Publishing |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 15:08 |
Last Modified: |
05 Dec 2022 14:21 |
Publisher DOI: |
10.1107/S0909049509012485 |
PubMed ID: |
19535875 |
Web of Science ID: |
000267047100020 |
URI: |
https://boris.unibe.ch/id/eprint/30014 (FactScience: 165770) |
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