Low-dose recombinant factor VIIa for massive bleeding: A single centre observational cohort study with 73 patients

Schmid, P; Mordasini, A; Luginbühl, M; Regli, B; Kohler, H P; Zimmermann, H; Inderbitzin, D; Hirt, A; Lämmle, B; Alberio, L (2011). Low-dose recombinant factor VIIa for massive bleeding: A single centre observational cohort study with 73 patients. Swiss medical weekly, 141, w13213. Muttenz: EMH Schweizerischer Ärzteverlag 10.4414/smw.2011.13213

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recombinant activated factor VII (rFVIIa) is used off-label for massive bleeding. There is no convincing evidence of the benefits of this practice and the minimal effective dose is unknown. The aim of the study was to evaluate our in-house guideline recommending a low dose of 60 μg/kg for off-label use of rFVIIa.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Intensive Care, Emergency Medicine and Anaesthesiology (DINA) > Clinic and Policlinic for Anaesthesiology and Pain Therapy
04 Faculty of Medicine > Department of Intensive Care, Emergency Medicine and Anaesthesiology (DINA) > Clinic of Intensive Care
04 Faculty of Medicine > Department of Intensive Care, Emergency Medicine and Anaesthesiology (DINA) > University Emergency Center
04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Visceral Surgery
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Haematology and Central Haematological Laboratory

UniBE Contributor:

Luginbühl, Martin; Regli, Bruno; Zimmermann, Heinz; Inderbitzin, Daniel; Lämmle, Bernhard and Alberio, Lorenzo

ISSN:

1424-7860

Publisher:

EMH Schweizerischer Ärzteverlag

Language:

English

Submitter:

Jeannie Wurz

Date Deposited:

04 Oct 2013 14:13

Last Modified:

23 Jan 2018 12:16

Publisher DOI:

10.4414/smw.2011.13213

PubMed ID:

21735365

Web of Science ID:

000292558000005

URI:

https://boris.unibe.ch/id/eprint/3056 (FactScience: 206332)

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