Theoulakis, Panagiotis; Goldblum, David; Zimmerli, Stefan; Muehlethaler, Konrad; Frueh, Beatrice E (2009). Keratitis resulting from Thielavia subthermophila Mouchacca. Cornea, 28(9), pp. 1067-9. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/ICO.0b013e31819717f4
Full text not available from this repository.PURPOSE: The purpose of this study was to report the first case of fungal keratitis resulting from Thielavia sp. METHODS: We conducted a retrospective chart review. RESULTS: A 10-year old girl presented 2 weeks after ocular plant injury with pain and corneal stromal infiltration with central ulceration and ill-defined margins. Cultures of corneal scrapings and biopsy sequence analysis of the ribosomal internal transcribed spacer region isolated Thielavia subthermophila Mouchacca. Clinically, the organism appeared to respond to topical amphotericin B and oral voriconazole. Best-corrected visual acuity at last follow-up visit counted 0.5. CONCLUSIONS: A rare case of Thielavia sp. keratitis was successfully treated with topical amphotericin B and oral voriconazole. Newly developed molecular diagnostic tools contribute to the recognition of a widening spectrum of emerging fungal pathogens capable of causing serious ocular infections.
Item Type: |
Journal Article (Further Contribution) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Service Sector > Institute for Infectious Diseases |
UniBE Contributor: |
Zimmerli, Stephan |
ISSN: |
0277-3740 |
Publisher: |
Lippincott Williams & Wilkins |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 15:14 |
Last Modified: |
02 Mar 2023 23:23 |
Publisher DOI: |
10.1097/ICO.0b013e31819717f4 |
PubMed ID: |
19724200 |
Web of Science ID: |
000271118400022 |
URI: |
https://boris.unibe.ch/id/eprint/32439 (FactScience: 197645) |
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